| month | day | visitor | score | home | score |
|---|
| November | 3, 2021 | Warriors | 93 | Suns | 113 |
| November | 5, 2021 | Suns | 92 | Knicks | 96 |
| November | 6, 2021 | Pistons | 102 | Suns | 110 |
| November | 7, 2021 | Suns | 84 | 76ers | 128 |
| November | 8, 2021 | Suns | 118 | Warriors | 119 |
| November | 10, 2021 | Spurs | 90 | Suns | 91 |
| November | 11, 2021 | Hornets | 65 | Suns | 122 |
| November | 13, 2021 | Celtics | 110 | Suns | 105 |
| November | 14, 2021 | Suns | 114 | Grizzlies | 103 |
| November | 16, 2021 | Timberwolves | 97 | Suns | 91 |
| November | 19, 2021 | Suns | 84 | Sonics | 110 |
| November | 20, 2021 | Heat | 101 | Suns | 74 |
| November | 24, 2021 | Sonics | 101 | Suns | 96 |
| November | 26, 2021 | Clippers | 99 | Suns | 65 |
| November | 28, 2021 | Suns | 98 | Jazz | 99 |
| November | 29, 2021 | Spurs | 96 | Suns | 94 |
| December | 1, 2021 | Warriors | 131 | Suns | 121 |
| December | 3, 2021 | Rockets | 89 | Suns | 80 |
| December | 8, 2021 | Suns | 107 | Nuggets | 77 |
| December | 10, 2021 | Knicks | 97 | Suns | 101 |
| December | 12, 2021 | Suns | 94 | Spurs | 102 |
| December | 14, 2021 | Suns | 98 | Nuggets | 100 |
| December | 15, 2021 | Jazz | 61 | Suns | 101 |
| December | 16, 2021 | Lakers | 102 | Suns | 122 |
| December | 17, 2021 | Suns | 85 | Hornets | 93 |
| December | 20, 2021 | Suns | 99 | Nuggets | 102 |
| December | 21, 2021 | Suns | 98 | Lakers | 94 |
| December | 22, 2021 | Suns | 94 | Sonics | 100 |
| December | 25, 2021 | Suns | 98 | Timberwolves | 102 |
| December | 26, 2021 | Nuggets | 112 | Suns | 102 |
| December | 27, 2021 | Nuggets | 89 | Suns | 98 |
| December | 30, 2021 | Suns | 120 | Celtics | 128 |
| December | 31, 2021 | Jazz | 64 | Suns | 97 |
| January | 2, 2022 | Bulls | 99 | Suns | 127 |
| January | 5, 2022 | Suns | 104 | Clippers | 101 |
| January | 6, 2022 | Suns | 88 | Rockets | 101 |
| January | 7, 2022 | Suns | 88 | Clippers | 91 |
| January | 8, 2022 | Sonics | 91 | Suns | 104 |
| January | 10, 2022 | Suns | 95 | Timberwolves | 91 |
| January | 13, 2022 | Suns | 116 | Warriors | 107 |
| January | 15, 2022 | Timberwolves | 84 | Suns | 96 |
| January | 16, 2022 | Warriors | 103 | Suns | 139 |
| January | 20, 2022 | Clippers | 121 | Suns | 91 |
| January | 24, 2022 | Suns | 108 | Cavaliers | 99 |
| January | 27, 2022 | Nuggets | 94 | Suns | 118 |
| January | 30, 2022 | Lakers | 91 | Suns | 96 |
| February | 9, 2022 | Suns | 115 | Lakers | 104 |
| February | 10, 2022 | Suns | 84 | Pistons | 110 |
| February | 12, 2022 | Suns | 115 | Rockets | 110 |
| February | 13, 2022 | 76ers | 118 | Suns | 107 |
| February | 17, 2022 | Timberwolves | 93 | Suns | 121 |
| February | 19, 2022 | Suns | 112 | Warriors | 114 |
| February | 22, 2022 | Clippers | 96 | Suns | 118 |
| February | 25, 2022 | Suns | 97 | Clippers | 108 |
| March | 2, 2022 | Suns | 105 | Nuggets | 100 |
| March | 5, 2022 | Sonics | 93 | Suns | 100 |
| March | 6, 2022 | Warriors | 104 | Suns | 110 |
| March | 7, 2022 | Suns | 100 | Spurs | 90 |
| March | 9, 2022 | Suns | 97 | Jazz | 92 |
| March | 13, 2022 | Grizzlies | 87 | Suns | 103 |
| March | 14, 2022 | Sonics | 113 | Suns | 101 |
| March | 17, 2022 | Suns | 85 | Jazz | 87 |
| March | 18, 2022 | Suns | 84 | Spurs | 110 |
| March | 20, 2022 | Cavaliers | 105 | Suns | 109 |
| March | 21, 2022 | Suns | | Lakers | |
| March | 22, 2022 | Rockets | | Suns | |
| March | 24, 2022 | Rockets | | Suns | |
| March | 27, 2022 | Clippers | | Suns | |
| March | 28, 2022 | Suns | | Clippers | |
| March | 29, 2022 | Suns | | Raptors | |
| March | 30, 2022 | Lakers | | Suns | |
| March | 31, 2022 | Lakers | | Suns | |
| April | 1, 2022 | Suns | | Timberwolves | |
| April | 5, 2022 | Jazz | | Suns | |
| April | 6, 2022 | Suns | | Spurs | |
| April | 8, 2022 | Suns | | Warriors | |
| April | 9, 2022 | Spurs | | Suns | |
| April | 13, 2022 | Raptors | | Suns | |
| April | 15, 2022 | Suns | | Sonics | |
| April | 17, 2022 | Suns | | Bulls | |
| April | 18, 2022 | Suns | | Heat | |
| April | 19, 2022 | Suns | | Rockets | |