| month | day | visitor | score | home | score |
|---|
| November | 2, 2022 | Warriors | 103 | Timberwolves | 124 |
| November | 4, 2022 | Clippers | 71 | Timberwolves | 93 |
| November | 6, 2022 | Timberwolves | 116 | Rockets | 128 |
| November | 9, 2022 | Jazz | 86 | Timberwolves | 108 |
| November | 10, 2022 | Timberwolves | 123 | Nuggets | 98 |
| November | 12, 2022 | Timberwolves | 109 | Warriors | 118 |
| November | 16, 2022 | Timberwolves | 96 | Suns | 103 |
| November | 17, 2022 | Timberwolves | 110 | Lakers | 115 |
| November | 18, 2022 | Knicks | 91 | Timberwolves | 95 |
| November | 19, 2022 | Pistons | 104 | Timberwolves | 114 |
| November | 20, 2022 | Nuggets | 114 | Timberwolves | 106 |
| November | 23, 2022 | Nuggets | 89 | Timberwolves | 130 |
| November | 27, 2022 | Clippers | 89 | Timberwolves | 85 |
| November | 30, 2022 | Clippers | 95 | Timberwolves | 114 |
| December | 3, 2022 | Lakers | 118 | Timberwolves | 126 |
| December | 4, 2022 | Timberwolves | 113 | Sonics | 107 |
| December | 5, 2022 | Timberwolves | 86 | Spurs | 98 |
| December | 11, 2022 | Timberwolves | 115 | Jazz | 108 |
| December | 12, 2022 | Timberwolves | 118 | Lakers | 107 |
| December | 13, 2022 | Timberwolves | 90 | Nuggets | 108 |
| December | 14, 2022 | Timberwolves | 69 | Spurs | 95 |
| December | 16, 2022 | Timberwolves | 88 | Clippers | 91 |
| December | 17, 2022 | Timberwolves | 102 | Bulls | 104 |
| December | 19, 2022 | Timberwolves | 94 | Jazz | 107 |
| December | 20, 2022 | Spurs | 90 | Timberwolves | 96 |
| December | 21, 2022 | Timberwolves | 109 | Heat | 103 |
| December | 22, 2022 | Timberwolves | 88 | Pistons | 117 |
| December | 24, 2022 | Jazz | 88 | Timberwolves | 95 |
| December | 25, 2022 | Suns | 81 | Timberwolves | 88 |
| December | 26, 2022 | Warriors | 90 | Timberwolves | 119 |
| January | 2, 2023 | Timberwolves | 90 | Nuggets | 107 |
| January | 3, 2023 | Timberwolves | 85 | Spurs | 88 |
| January | 5, 2023 | Rockets | 117 | Timberwolves | 87 |
| January | 10, 2023 | Suns | 85 | Timberwolves | 70 |
| January | 12, 2023 | Timberwolves | 90 | Clippers | 93 |
| January | 15, 2023 | Timberwolves | 96 | Suns | 104 |
| January | 19, 2023 | Timberwolves | 101 | Rockets | 129 |
| January | 20, 2023 | Jazz | 87 | Timberwolves | 81 |
| January | 21, 2023 | Timberwolves | 81 | Hornets | 93 |
| January | 22, 2023 | Timberwolves | 103 | Sonics | 101 |
| January | 23, 2023 | Celtics | 98 | Timberwolves | 81 |
| January | 24, 2023 | Rockets | 116 | Timberwolves | 92 |
| January | 26, 2023 | Timberwolves | 107 | Spurs | 91 |
| January | 28, 2023 | Timberwolves | 95 | Lakers | 102 |
| January | 30, 2023 | Nuggets | 103 | Timberwolves | 113 |
| January | 31, 2023 | Timberwolves | | Jazz | |
| February | 5, 2023 | Spurs | | Timberwolves | |
| February | 7, 2023 | Clippers | | Timberwolves | |
| February | 8, 2023 | 76ers | | Timberwolves | |
| February | 10, 2023 | Hornets | | Timberwolves | |
| February | 11, 2023 | Lakers | | Timberwolves | |
| February | 12, 2023 | Sonics | | Timberwolves | |
| February | 14, 2023 | Bulls | | Timberwolves | |
| February | 17, 2023 | Timberwolves | | Suns | |
| February | 18, 2023 | Timberwolves | | Warriors | |
| February | 23, 2023 | Jazz | | Timberwolves | |
| February | 24, 2023 | Timberwolves | | Raptors | |
| February | 26, 2023 | Rockets | | Timberwolves | |
| February | 27, 2023 | Timberwolves | | Jazz | |
| March | 2, 2023 | Timberwolves | | Warriors | |
| March | 3, 2023 | Timberwolves | | Cavaliers | |
| March | 4, 2023 | Sonics | | Timberwolves | |
| March | 7, 2023 | Timberwolves | | 76ers | |
| March | 11, 2023 | Cavaliers | | Timberwolves | |
| March | 12, 2023 | Timberwolves | | Rockets | |
| March | 15, 2023 | Lakers | | Timberwolves | |
| March | 16, 2023 | Timberwolves | | Rockets | |
| March | 19, 2023 | Sonics | | Timberwolves | |
| March | 21, 2023 | Timberwolves | | Sonics | |
| March | 22, 2023 | Lakers | | Timberwolves | |
| March | 23, 2023 | Grizzlies | | Timberwolves | |
| March | 25, 2023 | Warriors | | Timberwolves | |
| March | 28, 2023 | Heat | | Timberwolves | |
| March | 29, 2023 | Timberwolves | | Grizzlies | |
| April | 1, 2023 | Suns | | Timberwolves | |
| April | 3, 2023 | Raptors | | Timberwolves | |
| April | 9, 2023 | Timberwolves | | Clippers | |
| April | 12, 2023 | Sonics | | Timberwolves | |
| April | 14, 2023 | Timberwolves | | Celtics | |
| April | 16, 2023 | Spurs | | Timberwolves | |
| April | 17, 2023 | Timberwolves | | Knicks | |
| April | 20, 2023 | Timberwolves | | Nuggets | |