| month | day | visitor | score | home | score |
|---|
| November | 6, 2021 | Nuggets | 98 | Jazz | 94 |
| November | 8, 2021 | Nuggets | 79 | Spurs | 93 |
| November | 10, 2021 | Timberwolves | 110 | Nuggets | 104 |
| November | 11, 2021 | Lakers | 118 | Nuggets | 122 |
| November | 13, 2021 | Lakers | 114 | Nuggets | 108 |
| November | 14, 2021 | Nuggets | 87 | Jazz | 84 |
| November | 15, 2021 | Nuggets | 106 | Heat | 127 |
| November | 16, 2021 | Nuggets | 95 | Clippers | 114 |
| November | 18, 2021 | Spurs | 78 | Nuggets | 81 |
| November | 19, 2021 | Nuggets | 92 | Rockets | 112 |
| November | 20, 2021 | Nuggets | 101 | Timberwolves | 98 |
| November | 21, 2021 | Nuggets | 99 | Jazz | 98 |
| November | 23, 2021 | Nuggets | 98 | Timberwolves | 103 |
| November | 24, 2021 | Bulls | 112 | Nuggets | 98 |
| November | 25, 2021 | Jazz | 83 | Nuggets | 95 |
| November | 26, 2021 | Sonics | 109 | Nuggets | 106 |
| December | 1, 2021 | Rockets | 99 | Nuggets | 114 |
| December | 2, 2021 | Spurs | 93 | Nuggets | 73 |
| December | 4, 2021 | Nuggets | 97 | Clippers | 100 |
| December | 5, 2021 | Nuggets | 76 | Hornets | 93 |
| December | 8, 2021 | Suns | 107 | Nuggets | 77 |
| December | 10, 2021 | Celtics | 122 | Nuggets | 115 |
| December | 11, 2021 | Nuggets | 107 | Grizzlies | 104 |
| December | 13, 2021 | Timberwolves | 112 | Nuggets | 104 |
| December | 14, 2021 | Suns | 98 | Nuggets | 100 |
| December | 16, 2021 | Nuggets | 98 | Bulls | 102 |
| December | 18, 2021 | Nuggets | 94 | Jazz | 89 |
| December | 19, 2021 | Rockets | 102 | Nuggets | 105 |
| December | 20, 2021 | Suns | 99 | Nuggets | 102 |
| December | 21, 2021 | Warriors | 119 | Nuggets | 115 |
| December | 22, 2021 | Nuggets | 124 | Warriors | 117 |
| December | 24, 2021 | Nuggets | 103 | Lakers | 80 |
| December | 26, 2021 | Nuggets | 112 | Suns | 102 |
| December | 27, 2021 | Nuggets | 89 | Suns | 98 |
| December | 29, 2021 | Spurs | 79 | Nuggets | 90 |
| December | 30, 2021 | Nuggets | 100 | Raptors | 114 |
| January | 1, 2022 | Grizzlies | 106 | Nuggets | 109 |
| January | 2, 2022 | Timberwolves | 100 | Nuggets | 109 |
| January | 3, 2022 | Nuggets | 107 | Lakers | 96 |
| January | 6, 2022 | Nuggets | 112 | Warriors | 116 |
| January | 7, 2022 | Spurs | 104 | Nuggets | 112 |
| January | 8, 2022 | Knicks | 118 | Nuggets | 115 |
| January | 9, 2022 | Clippers | 113 | Nuggets | 116 |
| January | 11, 2022 | Raptors | 132 | Nuggets | 110 |
| January | 14, 2022 | Cavaliers | 110 | Nuggets | 111 |
| January | 21, 2022 | Lakers | 106 | Nuggets | 89 |
| January | 23, 2022 | Nuggets | 108 | Knicks | 112 |
| January | 24, 2022 | Warriors | 100 | Nuggets | 111 |
| January | 26, 2022 | Rockets | 114 | Nuggets | 118 |
| January | 27, 2022 | Nuggets | 94 | Suns | 118 |
| January | 29, 2022 | Nuggets | 90 | Sonics | 109 |
| January | 30, 2022 | Nuggets | 109 | Timberwolves | 99 |
| February | 7, 2022 | Nuggets | 97 | Celtics | 120 |
| February | 8, 2022 | Nuggets | 90 | Cavaliers | 121 |
| February | 9, 2022 | Sonics | 96 | Nuggets | 104 |
| February | 10, 2022 | Warriors | 115 | Nuggets | 87 |
| February | 14, 2022 | Nuggets | 102 | Sonics | 104 |
| February | 16, 2022 | Sonics | 85 | Nuggets | 91 |
| February | 17, 2022 | 76ers | 102 | Nuggets | 101 |
| February | 20, 2022 | Nuggets | 95 | Rockets | 115 |
| February | 24, 2022 | Nuggets | 114 | Rockets | 107 |
| February | 25, 2022 | Nuggets | 89 | Pistons | 87 |
| February | 28, 2022 | Nuggets | 112 | Spurs | 103 |
| March | 1, 2022 | Nuggets | 120 | Lakers | 111 |
| March | 2, 2022 | Suns | 105 | Nuggets | 100 |
| March | 5, 2022 | Rockets | 107 | Nuggets | 125 |
| March | 8, 2022 | Nuggets | 94 | Clippers | 90 |
| March | 10, 2022 | Spurs | 92 | Nuggets | 84 |
| March | 12, 2022 | Pistons | 118 | Nuggets | 113 |
| March | 13, 2022 | Nuggets | 92 | Sonics | 114 |
| March | 24, 2022 | Clippers | 95 | Nuggets | 99 |
| March | 28, 2022 | Warriors | 112 | Nuggets | 109 |
| March | 29, 2022 | Nuggets | 103 | Lakers | 106 |
| March | 31, 2022 | Hornets | 91 | Nuggets | 96 |
| April | 1, 2022 | Nuggets | 102 | Sonics | 107 |
| April | 3, 2022 | Nuggets | 97 | Warriors | 117 |
| April | 8, 2022 | Nuggets | 117 | 76ers | 128 |
| April | 12, 2022 | Nuggets | 120 | Jazz | 89 |
| April | 15, 2022 | Heat | 114 | Nuggets | 96 |
| April | 16, 2022 | Nuggets | 115 | Clippers | 111 |
| April | 18, 2022 | Jazz | 97 | Nuggets | 105 |
| April | 20, 2022 | Timberwolves | 100 | Nuggets | 124 |
| Post | 1, 2022 | Nuggets | 108 | Suns | 89 |
| Post | 2, 2022 | Nuggets | 100 | Suns | 105 |
| Post | 3, 2022 | Suns | 84 | Nuggets | 120 |
| Post | 4, 2022 | Suns | 93 | Nuggets | 95 |
| Post | 5, 2022 | Nuggets | 98 | Suns | 118 |
| Post | 6, 2022 | Suns | 92 | Nuggets | 112 |
| Post | 7, 2022 | Nuggets | | Suns | |
| Post | 8, 2022 | Nuggets | 95 | Sonics | 102 |
| Post | 9, 2022 | Nuggets | 106 | Sonics | 112 |
| Post | 10, 2022 | Sonics | 102 | Nuggets | 107 |
| Post | 11, 2022 | Sonics | 106 | Nuggets | 112 |
| Post | 12, 2022 | Nuggets | 119 | Sonics | 118 |
| Post | 13, 2022 | Sonics | 92 | Nuggets | 120 |
| Post | 14, 2022 | Nuggets | | Sonics | |
| Post | 15, 2022 | Spurs | 102 | Nuggets | 109 |
| Post | 16, 2022 | Spurs | 104 | Nuggets | 109 |
| Post | 17, 2022 | Nuggets | 108 | Spurs | 98 |
| Post | 18, 2022 | Nuggets | 95 | Spurs | 111 |
| Post | 19, 2022 | Spurs | 95 | Nuggets | 87 |
| Post | 20, 2022 | Nuggets | 94 | Spurs | 95 |
| Post | 21, 2022 | Spurs | 96 | Nuggets | 86 |