| month | day | visitor | score | home | score |
|---|
| November | 2, 2022 | Raptors | 107 | Grizzlies | 106 |
| November | 3, 2022 | Grizzlies | 78 | Clippers | 84 |
| November | 4, 2022 | Grizzlies | 99 | Timberwolves | 96 |
| November | 9, 2022 | Knicks | 90 | Grizzlies | 130 |
| November | 10, 2022 | 76ers | 71 | Grizzlies | 92 |
| November | 13, 2022 | Grizzlies | 106 | Celtics | 120 |
| November | 14, 2022 | Grizzlies | 95 | Hornets | 105 |
| November | 17, 2022 | Grizzlies | 91 | Pistons | 126 |
| November | 18, 2022 | Grizzlies | 82 | Suns | 100 |
| November | 19, 2022 | 76ers | 75 | Grizzlies | 90 |
| November | 20, 2022 | 76ers | 91 | Grizzlies | 103 |
| November | 22, 2022 | Pistons | 115 | Grizzlies | 83 |
| November | 23, 2022 | Jazz | 98 | Grizzlies | 95 |
| November | 24, 2022 | Hornets | 85 | Grizzlies | 105 |
| November | 25, 2022 | Grizzlies | 114 | Knicks | 103 |
| November | 26, 2022 | Pistons | 130 | Grizzlies | 125 |
| November | 29, 2022 | Grizzlies | 78 | Hornets | 89 |
| November | 30, 2022 | Grizzlies | 84 | Heat | 124 |
| December | 3, 2022 | Celtics | 117 | Grizzlies | 98 |
| December | 7, 2022 | Grizzlies | 109 | Heat | 125 |
| December | 11, 2022 | Grizzlies | 99 | Bulls | 113 |
| December | 12, 2022 | Grizzlies | 92 | Pistons | 110 |
| December | 13, 2022 | Timberwolves | 106 | Grizzlies | 98 |
| December | 15, 2022 | Grizzlies | 110 | Bulls | 96 |
| December | 16, 2022 | Grizzlies | 90 | 76ers | 85 |
| December | 18, 2022 | Bulls | 101 | Grizzlies | 108 |
| December | 21, 2022 | Spurs | 81 | Grizzlies | 95 |
| December | 25, 2022 | Grizzlies | 101 | Cavaliers | 92 |
| December | 29, 2022 | Grizzlies | 89 | Knicks | 102 |
| January | 4, 2023 | Grizzlies | 113 | Pistons | 103 |
| January | 7, 2023 | Hornets | 84 | Grizzlies | 90 |
| January | 8, 2023 | Grizzlies | 72 | Hornets | 91 |
| January | 9, 2023 | Grizzlies | 105 | Nuggets | 113 |
| January | 10, 2023 | Sonics | 85 | Grizzlies | 119 |
| January | 12, 2023 | Grizzlies | 87 | Cavaliers | 105 |
| January | 13, 2023 | Grizzlies | 88 | 76ers | 64 |
| January | 14, 2023 | Grizzlies | 88 | Raptors | 121 |
| January | 17, 2023 | Celtics | 105 | Grizzlies | 99 |
| January | 19, 2023 | Grizzlies | 103 | Lakers | 100 |
| January | 20, 2023 | Pistons | 122 | Grizzlies | 131 |
| January | 22, 2023 | Cavaliers | 102 | Grizzlies | 106 |
| January | 24, 2023 | Grizzlies | 103 | Bulls | 95 |
| January | 28, 2023 | Cavaliers | 100 | Grizzlies | 102 |
| January | 29, 2023 | Warriors | 119 | Grizzlies | 125 |
| January | 30, 2023 | Grizzlies | 99 | Celtics | 113 |
| February | 6, 2023 | Knicks | 92 | Grizzlies | 103 |
| February | 7, 2023 | Grizzlies | 104 | Knicks | 86 |
| February | 9, 2023 | Grizzlies | 86 | Raptors | 112 |
| February | 13, 2023 | Lakers | 85 | Grizzlies | 110 |
| February | 14, 2023 | Grizzlies | 88 | Hornets | 84 |
| February | 16, 2023 | Grizzlies | 98 | Knicks | 90 |
| February | 17, 2023 | Bulls | 86 | Grizzlies | 111 |
| February | 18, 2023 | Rockets | 89 | Grizzlies | 94 |
| February | 19, 2023 | Grizzlies | 101 | Bulls | 114 |
| February | 20, 2023 | Heat | 123 | Grizzlies | 91 |
| February | 22, 2023 | Knicks | 107 | Grizzlies | 90 |
| February | 24, 2023 | Heat | 112 | Grizzlies | 106 |
| February | 25, 2023 | Grizzlies | 81 | Celtics | 106 |
| February | 26, 2023 | Grizzlies | 99 | Warriors | 109 |
| February | 27, 2023 | Grizzlies | 95 | Jazz | 98 |
| February | 28, 2023 | Celtics | 97 | Grizzlies | 92 |
| March | 4, 2023 | Grizzlies | 80 | Raptors | 96 |
| March | 5, 2023 | Grizzlies | 79 | Spurs | 83 |
| March | 6, 2023 | Grizzlies | 98 | Cavaliers | 86 |
| March | 7, 2023 | Grizzlies | 105 | Rockets | 97 |
| March | 10, 2023 | Raptors | 94 | Grizzlies | 103 |
| March | 13, 2023 | Raptors | 94 | Grizzlies | 90 |
| March | 14, 2023 | Raptors | 110 | Grizzlies | 92 |
| March | 19, 2023 | Grizzlies | 82 | 76ers | 97 |
| March | 23, 2023 | Cavaliers | 80 | Grizzlies | 92 |
| March | 26, 2023 | Bulls | 92 | Grizzlies | 87 |
| March | 27, 2023 | Heat | 113 | Grizzlies | 83 |
| March | 28, 2023 | Grizzlies | 98 | Sonics | 92 |
| March | 29, 2023 | Grizzlies | 103 | Heat | 97 |
| March | 31, 2023 | Hornets | 80 | Grizzlies | 100 |
| April | 4, 2023 | Clippers | 79 | Grizzlies | 107 |
| April | 5, 2023 | Cavaliers | 93 | Grizzlies | 86 |
| April | 6, 2023 | Pistons | 107 | Grizzlies | 95 |
| April | 8, 2023 | Suns | 94 | Grizzlies | 83 |
| April | 14, 2023 | Bulls | 100 | Grizzlies | 101 |
| April | 15, 2023 | Grizzlies | 95 | Pistons | 99 |
| April | 18, 2023 | Nuggets | 117 | Grizzlies | 109 |
| Post | 1, 2023 | Grizzlies | 101 | Pistons | 97 |
| Post | 2, 2023 | Grizzlies | 85 | Pistons | 99 |
| Post | 3, 2023 | Pistons | 107 | Grizzlies | 101 |
| Post | 4, 2023 | Pistons | 103 | Grizzlies | 97 |
| Post | 5, 2023 | Grizzlies | 94 | Pistons | 107 |
| Post | 6, 2023 | Pistons | | Grizzlies | |
| Post | 7, 2023 | Grizzlies | | Pistons | |