| month | day | visitor | score | home | score |
|---|
| November | 2, 2022 | Grizzlies | 85 | Heat | 129 |
| November | 3, 2022 | Grizzlies | 97 | 76ers | 88 |
| November | 5, 2022 | Cavaliers | 83 | Grizzlies | 93 |
| November | 7, 2022 | Grizzlies | 90 | Raptors | 111 |
| November | 12, 2022 | Pistons | 119 | Grizzlies | 99 |
| November | 14, 2022 | Suns | 95 | Grizzlies | 79 |
| November | 15, 2022 | Jazz | 82 | Grizzlies | 110 |
| November | 18, 2022 | Hornets | 100 | Grizzlies | 87 |
| November | 21, 2022 | Spurs | 95 | Grizzlies | 93 |
| November | 22, 2022 | Knicks | 117 | Grizzlies | 112 |
| November | 23, 2022 | Grizzlies | 102 | Cavaliers | 90 |
| November | 25, 2022 | Grizzlies | 90 | Bulls | 89 |
| November | 26, 2022 | Grizzlies | 102 | 76ers | 88 |
| December | 2, 2022 | Grizzlies | 66 | Hornets | 95 |
| December | 3, 2022 | Grizzlies | 112 | Heat | 110 |
| December | 5, 2022 | Celtics | 114 | Grizzlies | 86 |
| December | 6, 2022 | Sonics | 89 | Grizzlies | 106 |
| December | 7, 2022 | Knicks | 97 | Grizzlies | 96 |
| December | 8, 2022 | Lakers | 90 | Grizzlies | 92 |
| December | 11, 2022 | Nuggets | 110 | Grizzlies | 85 |
| December | 17, 2022 | Cavaliers | 103 | Grizzlies | 87 |
| December | 18, 2022 | Bulls | 99 | Grizzlies | 93 |
| December | 19, 2022 | Warriors | 102 | Grizzlies | 90 |
| December | 20, 2022 | Grizzlies | 65 | Rockets | 107 |
| December | 21, 2022 | Pistons | 95 | Grizzlies | 64 |
| December | 28, 2022 | Grizzlies | 93 | Hornets | 91 |
| December | 29, 2022 | Cavaliers | 93 | Grizzlies | 85 |
| December | 30, 2022 | Hornets | 87 | Grizzlies | 72 |
| December | 31, 2022 | Bulls | 89 | Grizzlies | 77 |
| January | 1, 2023 | Grizzlies | 101 | Nuggets | 114 |
| January | 2, 2023 | Pistons | 103 | Grizzlies | 91 |
| January | 4, 2023 | Grizzlies | 86 | Celtics | 108 |
| January | 5, 2023 | Grizzlies | 122 | Pistons | 116 |
| January | 10, 2023 | Grizzlies | 90 | Celtics | 118 |
| January | 12, 2023 | Grizzlies | 101 | Warriors | 99 |
| January | 16, 2023 | Celtics | 107 | Grizzlies | 92 |
| January | 17, 2023 | Grizzlies | 101 | Hornets | 90 |
| January | 18, 2023 | Grizzlies | 92 | Raptors | 110 |
| January | 20, 2023 | Grizzlies | 102 | Pistons | 115 |
| January | 22, 2023 | Grizzlies | 109 | Bulls | 96 |
| January | 24, 2023 | Grizzlies | 118 | Heat | 107 |
| February | 8, 2023 | Celtics | | Grizzlies | |
| February | 12, 2023 | Grizzlies | | Spurs | |
| February | 13, 2023 | Grizzlies | | Knicks | |
| February | 16, 2023 | Grizzlies | | Knicks | |
| February | 17, 2023 | Bulls | | Grizzlies | |
| February | 19, 2023 | Pistons | | Grizzlies | |
| February | 20, 2023 | Raptors | | Grizzlies | |
| February | 24, 2023 | Heat | | Grizzlies | |
| February | 25, 2023 | Raptors | | Grizzlies | |
| February | 27, 2023 | Clippers | | Grizzlies | |
| February | 28, 2023 | Bulls | | Grizzlies | |
| March | 1, 2023 | Grizzlies | | Knicks | |
| March | 2, 2023 | Grizzlies | | Celtics | |
| March | 5, 2023 | Cavaliers | | Grizzlies | |
| March | 6, 2023 | Grizzlies | | Jazz | |
| March | 8, 2023 | Grizzlies | | Hornets | |
| March | 10, 2023 | Grizzlies | | Pistons | |
| March | 11, 2023 | Knicks | | Grizzlies | |
| March | 12, 2023 | 76ers | | Grizzlies | |
| March | 13, 2023 | Grizzlies | | Suns | |
| March | 14, 2023 | Grizzlies | | Cavaliers | |
| March | 15, 2023 | Heat | | Grizzlies | |
| March | 17, 2023 | Grizzlies | | Cavaliers | |
| March | 19, 2023 | Grizzlies | | Bulls | |
| March | 21, 2023 | Raptors | | Grizzlies | |
| March | 22, 2023 | Grizzlies | | 76ers | |
| March | 23, 2023 | Grizzlies | | Timberwolves | |
| March | 24, 2023 | Grizzlies | | Lakers | |
| March | 25, 2023 | Hornets | | Grizzlies | |
| March | 27, 2023 | Grizzlies | | Raptors | |
| March | 28, 2023 | Rockets | | Grizzlies | |
| March | 29, 2023 | Timberwolves | | Grizzlies | |
| March | 30, 2023 | Grizzlies | | Clippers | |
| April | 2, 2023 | Raptors | | Grizzlies | |
| April | 4, 2023 | 76ers | | Grizzlies | |
| April | 6, 2023 | Grizzlies | | Sonics | |
| April | 10, 2023 | Grizzlies | | Pistons | |
| April | 11, 2023 | Grizzlies | | Knicks | |
| April | 14, 2023 | 76ers | | Grizzlies | |
| April | 16, 2023 | Heat | | Grizzlies | |
| April | 20, 2023 | Grizzlies | | Bulls | |