| month | day | visitor | score | home | score |
|---|
| November | 4, 2020 | Nuggets | 132 | Wolves | 120 |
| November | 6, 2020 | Grizzlies | 100 | Wolves | 97 |
| November | 8, 2020 | Wolves | 127 | Clippers | 132 |
| November | 10, 2020 | Spurs | 99 | Wolves | 117 |
| November | 12, 2020 | Kings | 109 | Wolves | 110 |
| November | 13, 2020 | Nuggets | 109 | Wolves | 123 |
| November | 14, 2020 | Lakers | 127 | Wolves | 117 |
| November | 16, 2020 | Wolves | 108 | Rockets | 122 |
| November | 19, 2020 | Bulls | 106 | Wolves | 118 |
| November | 21, 2020 | Wolves | 102 | Raptors | 116 |
| November | 22, 2020 | Wolves | 101 | Nets | 118 |
| November | 23, 2020 | Rockets | 125 | Wolves | 121 |
| November | 25, 2020 | Wolves | 127 | Kings | 120 |
| November | 27, 2020 | Mavericks | 97 | Wolves | 89 |
| November | 28, 2020 | Suns | 112 | Wolves | 116 |
| November | 30, 2020 | Wolves | 116 | Sonics | 99 |
| December | 4, 2020 | Warriors | 115 | Wolves | 97 |
| December | 6, 2020 | Wolves | 124 | Warriors | 142 |
| December | 8, 2020 | Wolves | 121 | Spurs | 131 |
| December | 9, 2020 | Wolves | 120 | Grizzlies | 119 |
| December | 15, 2020 | Clippers | 100 | Wolves | 101 |
| December | 16, 2020 | Wolves | 148 | Pelicans | 145 |
| December | 19, 2020 | Bucks | 113 | Wolves | 134 |
| December | 20, 2020 | Blazers | 133 | Wolves | 126 |
| December | 23, 2020 | Raptors | 109 | Wolves | 143 |
| January | 4, 2021 | Wolves | 105 | Celtics | 116 |
| January | 8, 2021 | 76ers | 102 | Wolves | 101 |
| January | 13, 2021 | Mavericks | 91 | Wolves | 85 |
| January | 14, 2021 | Spurs | 132 | Wolves | 116 |
| January | 18, 2021 | Sonics | 101 | Wolves | 134 |
| January | 19, 2021 | Wolves | 134 | Blazers | 133 |
| January | 20, 2021 | Wolves | 110 | Jazz | 107 |
| January | 21, 2021 | Wolves | 124 | Blazers | 122 |
| January | 23, 2021 | Wolves | 114 | 76ers | 106 |
| January | 24, 2021 | Suns | 125 | Wolves | 102 |
| January | 25, 2021 | Hawks | 127 | Wolves | 113 |
| January | 27, 2021 | Wolves | 112 | Bucks | 126 |
| January | 28, 2021 | Wolves | 94 | Jazz | 89 |
| January | 29, 2021 | Wolves | 150 | Bulls | 133 |
| January | 30, 2021 | Celtics | 122 | Wolves | 92 |
| January | 31, 2021 | Jazz | 126 | Wolves | 108 |
| February | 2, 2021 | Mavericks | 94 | Wolves | 88 |
| February | 11, 2021 | Wolves | 116 | Jazz | 130 |
| February | 18, 2021 | Wolves | 111 | Knicks | 110 |
| February | 22, 2021 | Wolves | 109 | Nuggets | 104 |
| February | 23, 2021 | Wolves | 96 | Mavericks | 102 |
| February | 24, 2021 | Wolves | 131 | Spurs | 130 |
| February | 26, 2021 | Rockets | 130 | Wolves | 115 |
| February | 27, 2021 | Wolves | 94 | Warriors | 114 |
| February | 28, 2021 | Wolves | 112 | Suns | 120 |
| March | 2, 2021 | Wolves | 102 | Lakers | 119 |
| March | 3, 2021 | Wolves | 98 | Nuggets | 100 |
| March | 10, 2021 | Wolves | 97 | Mavericks | 102 |
| March | 14, 2021 | Wolves | 114 | Rockets | 134 |
| March | 15, 2021 | Kings | 101 | Wolves | 113 |
| March | 17, 2021 | Suns | 94 | Wolves | 119 |
| March | 20, 2021 | Wolves | 111 | Mavericks | 109 |
| March | 24, 2021 | Nuggets | 99 | Wolves | 106 |
| March | 25, 2021 | Wolves | 122 | Hawks | 128 |
| March | 26, 2021 | Pacers | 136 | Wolves | 132 |
| March | 27, 2021 | Wolves | 113 | Lakers | 126 |
| March | 29, 2021 | Jazz | 86 | Wolves | 120 |
| March | 31, 2021 | Wolves | 115 | Rockets | 114 |
| April | 1, 2021 | Blazers | 112 | Wolves | 122 |
| April | 3, 2021 | Spurs | 89 | Wolves | 117 |
| April | 4, 2021 | Wolves | 108 | Nuggets | 114 |
| April | 5, 2021 | Heat | 86 | Wolves | 80 |
| April | 6, 2021 | Jazz | 130 | Wolves | 103 |
| April | 7, 2021 | Rockets | 110 | Wolves | 113 |
| April | 12, 2021 | Wolves | 99 | Clippers | 125 |
| April | 13, 2021 | Wolves | 105 | Spurs | 111 |
| April | 14, 2021 | Wolves | 101 | Kings | 95 |
| April | 15, 2021 | Wolves | 84 | Heat | 86 |
| April | 16, 2021 | Clippers | 104 | Wolves | 126 |
| April | 17, 2021 | Knicks | 124 | Wolves | 121 |
| April | 18, 2021 | Wolves | 96 | Pacers | 113 |
| April | 19, 2021 | Pelicans | 142 | Wolves | 119 |
| April | 20, 2021 | Warriors | 105 | Wolves | 144 |
| April | 21, 2021 | Lakers | 108 | Wolves | 113 |
| April | 22, 2021 | Wolves | 114 | Suns | 95 |
| April | 24, 2021 | Wolves | 103 | Sonics | 112 |
| April | 26, 2021 | Nets | 118 | Wolves | 77 |
| Post | 1, 2021 | Wolves | 101 | Mavericks | 86 |
| Post | 2, 2021 | Wolves | 100 | Mavericks | 96 |
| Post | 3, 2021 | Mavericks | 95 | Wolves | 117 |
| Post | 4, 2021 | Mavericks | 102 | Wolves | 109 |
| Post | 5, 2021 | Wolves | | Mavericks | |
| Post | 6, 2021 | Mavericks | | Wolves | |
| Post | 7, 2021 | Wolves | | Mavericks | |
| Post | 8, 2021 | Wolves | 115 | Lakers | 123 |
| Post | 9, 2021 | Wolves | 101 | Lakers | 129 |
| Post | 10, 2021 | Lakers | 110 | Wolves | 101 |
| Post | 11, 2021 | Lakers | 132 | Wolves | 123 |
| Post | 12, 2021 | Wolves | | Lakers | |
| Post | 13, 2021 | Lakers | | Wolves | |
| Post | 14, 2021 | Wolves | | Lakers | |