| month | day | visitor | score | home | score |
|---|
| November | 3, 2022 | Knicks | 107 | 76ers | 86 |
| November | 4, 2022 | 76ers | 70 | Bucks | 90 |
| November | 5, 2022 | 76ers | 88 | Celtics | 113 |
| November | 6, 2022 | Blazers | 82 | 76ers | 76 |
| November | 7, 2022 | 76ers | 93 | Knicks | 118 |
| November | 9, 2022 | Bulls | 117 | 76ers | 112 |
| November | 14, 2022 | 76ers | 86 | Bulls | 107 |
| November | 18, 2022 | Bucks | 86 | 76ers | 81 |
| November | 22, 2022 | 76ers | 96 | Pacers | 120 |
| November | 23, 2022 | Celtics | 117 | 76ers | 115 |
| November | 24, 2022 | 76ers | 70 | Nets | 95 |
| November | 27, 2022 | 76ers | 85 | Kings | 108 |
| November | 29, 2022 | Pacers | 126 | 76ers | 125 |
| December | 2, 2022 | Heat | 111 | 76ers | 98 |
| December | 3, 2022 | 76ers | 98 | Nuggets | 123 |
| December | 4, 2022 | Rockets | 97 | 76ers | 99 |
| December | 5, 2022 | 76ers | 100 | Heat | 97 |
| December | 7, 2022 | Warriors | 101 | 76ers | 87 |
| December | 12, 2022 | 76ers | 83 | Knicks | 126 |
| December | 13, 2022 | 76ers | 86 | Nets | 102 |
| December | 17, 2022 | 76ers | 87 | Bucks | 89 |
| December | 18, 2022 | Pelicans | 101 | 76ers | 87 |
| December | 20, 2022 | Hawks | 119 | 76ers | 108 |
| December | 21, 2022 | Raptors | 106 | 76ers | 110 |
| December | 23, 2022 | 76ers | 86 | Pelicans | 118 |
| December | 25, 2022 | Grizzlies | 82 | 76ers | 89 |
| December | 26, 2022 | 76ers | 100 | Celtics | 135 |
| December | 27, 2022 | 76ers | 85 | Suns | 105 |
| December | 28, 2022 | Heat | 82 | 76ers | 98 |
| December | 30, 2022 | 76ers | 106 | Knicks | 123 |
| January | 2, 2023 | Heat | 107 | 76ers | 114 |
| January | 4, 2023 | Grizzlies | 106 | 76ers | 87 |
| January | 6, 2023 | 76ers | 93 | Celtics | 121 |
| January | 7, 2023 | Mavericks | 94 | 76ers | 99 |
| January | 8, 2023 | 76ers | 80 | Wolves | 116 |
| January | 13, 2023 | 76ers | 114 | Nets | 120 |
| January | 14, 2023 | Bucks | 109 | 76ers | 80 |
| January | 15, 2023 | Kings | 108 | 76ers | 88 |
| January | 17, 2023 | Jazz | 119 | 76ers | 74 |
| January | 19, 2023 | 76ers | 84 | Warriors | 110 |
| January | 22, 2023 | Celtics | 118 | 76ers | 95 |
| January | 23, 2023 | Wolves | 114 | 76ers | 104 |
| January | 25, 2023 | 76ers | 66 | Rockets | 104 |
| January | 29, 2023 | Knicks | 111 | 76ers | 79 |
| January | 30, 2023 | 76ers | 89 | Bulls | 121 |
| January | 31, 2023 | 76ers | 106 | Sonics | 127 |
| February | 8, 2023 | 76ers | 111 | Raptors | 119 |
| February | 9, 2023 | 76ers | 87 | Lakers | 108 |
| February | 10, 2023 | 76ers | 66 | Blazers | 125 |
| February | 11, 2023 | Raptors | 115 | 76ers | 108 |
| February | 12, 2023 | 76ers | 123 | Clippers | 111 |
| February | 13, 2023 | 76ers | 80 | Grizzlies | 104 |
| February | 14, 2023 | Pelicans | 124 | 76ers | 105 |
| February | 15, 2023 | Nets | 109 | 76ers | 90 |
| February | 17, 2023 | 76ers | 115 | Hawks | 113 |
| February | 19, 2023 | Knicks | 126 | 76ers | 101 |
| February | 20, 2023 | 76ers | 93 | Mavericks | 115 |
| February | 23, 2023 | Clippers | 125 | 76ers | 112 |
| February | 26, 2023 | Nets | 110 | 76ers | 83 |
| February | 28, 2023 | 76ers | 90 | Spurs | 105 |
| March | 1, 2023 | Lakers | 76 | 76ers | 83 |
| March | 5, 2023 | 76ers | 97 | Grizzlies | 116 |
| March | 7, 2023 | 76ers | 68 | Celtics | 128 |
| March | 10, 2023 | Hawks | 134 | 76ers | 95 |
| March | 11, 2023 | 76ers | 102 | Jazz | 112 |
| March | 12, 2023 | 76ers | 84 | Pelicans | 110 |
| March | 14, 2023 | 76ers | 89 | Hawks | 134 |
| March | 16, 2023 | Raptors | 120 | 76ers | 92 |
| March | 21, 2023 | Bulls | 107 | 76ers | 73 |
| March | 27, 2023 | Pelicans | 129 | 76ers | 97 |
| March | 29, 2023 | 76ers | 82 | Pacers | 114 |
| March | 30, 2023 | Sonics | 119 | 76ers | 95 |
| March | 31, 2023 | 76ers | 93 | Raptors | 130 |
| April | 2, 2023 | 76ers | 84 | Heat | 111 |
| April | 6, 2023 | 76ers | 96 | Heat | 124 |
| April | 8, 2023 | Spurs | 79 | 76ers | 99 |
| April | 9, 2023 | Bulls | 125 | 76ers | 100 |
| April | 12, 2023 | Pacers | 114 | 76ers | 90 |
| April | 13, 2023 | 76ers | 94 | Pelicans | 119 |
| April | 16, 2023 | Nuggets | 103 | 76ers | 95 |
| April | 18, 2023 | Nets | 121 | 76ers | 104 |
| April | 19, 2023 | Suns | 119 | 76ers | 111 |