| month | day | visitor | score | home | score |
|---|
| November | 5, 2020 | 76ers | 107 | Knicks | 109 |
| November | 6, 2020 | Cavaliers | 97 | Knicks | 81 |
| November | 7, 2020 | Knicks | 97 | Wolves | 83 |
| November | 9, 2020 | Knicks | 107 | Jazz | 103 |
| November | 10, 2020 | Knicks | 104 | Pistons | 100 |
| November | 12, 2020 | Knicks | 117 | Grizzlies | 104 |
| November | 14, 2020 | Knicks | 95 | Pacers | 79 |
| November | 18, 2020 | Knicks | 93 | Wizards | 102 |
| November | 19, 2020 | Pelicans | 94 | Knicks | 81 |
| November | 21, 2020 | Wolves | 88 | Knicks | 105 |
| November | 22, 2020 | Bobcats | 100 | Knicks | 93 |
| November | 24, 2020 | Nets | 96 | Knicks | 106 |
| November | 25, 2020 | Rockets | 94 | Knicks | 103 |
| November | 28, 2020 | Knicks | 103 | Kings | 112 |
| December | 1, 2020 | Knicks | 89 | Bobcats | 100 |
| December | 4, 2020 | Knicks | 102 | Raptors | 93 |
| December | 5, 2020 | Warriors | 93 | Knicks | 89 |
| December | 8, 2020 | Knicks | 91 | Pistons | 94 |
| December | 12, 2020 | Knicks | 108 | Lakers | 100 |
| December | 13, 2020 | Knicks | 86 | Pelicans | 102 |
| December | 15, 2020 | Knicks | 79 | Bulls | 114 |
| December | 17, 2020 | Hawks | 87 | Knicks | 112 |
| December | 21, 2020 | Knicks | 87 | Raptors | 116 |
| December | 26, 2020 | Knicks | 105 | Bulls | 117 |
| December | 28, 2020 | Magic | 99 | Knicks | 89 |
| December | 29, 2020 | Jazz | 100 | Knicks | 92 |
| December | 30, 2020 | Celtics | 83 | Knicks | 87 |
| January | 2, 2021 | Knicks | 99 | Rockets | 89 |
| January | 4, 2021 | Knicks | 87 | Nets | 98 |
| January | 5, 2021 | Hawks | 68 | Knicks | 109 |
| January | 9, 2021 | Suns | 91 | Knicks | 114 |
| January | 13, 2021 | Knicks | 78 | Pacers | 87 |
| January | 14, 2021 | Knicks | 101 | Nuggets | 91 |
| January | 15, 2021 | Knicks | 126 | Cavaliers | 84 |
| January | 16, 2021 | Knicks | 112 | Celtics | 101 |
| January | 22, 2021 | Grizzlies | 98 | Knicks | 119 |
| January | 24, 2021 | Knicks | 87 | 76ers | 78 |
| January | 30, 2021 | Bucks | 94 | Knicks | 105 |
| January | 31, 2021 | Spurs | 83 | Knicks | 103 |
| February | 2, 2021 | Knicks | 79 | Heat | 100 |
| February | 4, 2021 | 76ers | 72 | Knicks | 87 |
| February | 5, 2021 | Blazers | 90 | Knicks | 103 |
| February | 14, 2021 | Knicks | 106 | Blazers | 94 |
| February | 15, 2021 | Celtics | 88 | Knicks | 87 |
| February | 18, 2021 | Kings | 99 | Knicks | 117 |
| February | 19, 2021 | Bulls | 118 | Knicks | 98 |
| February | 20, 2021 | Knicks | 99 | Hawks | 88 |
| February | 21, 2021 | Cavaliers | 76 | Knicks | 107 |
| February | 22, 2021 | Bobcats | 80 | Knicks | 107 |
| February | 23, 2021 | Wizards | 90 | Knicks | 113 |
| February | 27, 2021 | Knicks | 88 | Spurs | 95 |
| March | 1, 2021 | Knicks | 82 | Bucks | 110 |
| March | 4, 2021 | Knicks | 96 | 76ers | 107 |
| March | 5, 2021 | Nuggets | 82 | Knicks | 86 |
| March | 7, 2021 | Knicks | 80 | Clippers | 111 |
| March | 8, 2021 | Knicks | 92 | Bobcats | 107 |
| March | 9, 2021 | Knicks | 103 | Magic | 94 |
| March | 15, 2021 | Knicks | 93 | Wizards | 108 |
| March | 17, 2021 | Knicks | 94 | Warriors | 104 |
| March | 18, 2021 | Pistons | 110 | Knicks | 111 |
| March | 19, 2021 | Heat | 78 | Knicks | 90 |
| March | 26, 2021 | Heat | 105 | Knicks | 85 |
| March | 27, 2021 | Pistons | 84 | Knicks | 112 |
| March | 30, 2021 | Pacers | 89 | Knicks | 96 |
| April | 1, 2021 | Wizards | 96 | Knicks | 86 |
| April | 2, 2021 | Bulls | 127 | Knicks | 115 |
| April | 3, 2021 | Clippers | 96 | Knicks | 114 |
| April | 5, 2021 | Sonics | 115 | Knicks | 117 |
| April | 6, 2021 | Pacers | 69 | Knicks | 101 |
| April | 7, 2021 | Knicks | 91 | Nets | 97 |
| April | 12, 2021 | Raptors | 99 | Knicks | 69 |
| April | 16, 2021 | Knicks | 110 | Hawks | 99 |
| April | 17, 2021 | Knicks | 110 | Cavaliers | 85 |
| April | 19, 2021 | Knicks | 86 | Magic | 90 |
| April | 21, 2021 | Knicks | 89 | Bucks | 93 |
| April | 22, 2021 | Mavericks | 97 | Knicks | 101 |
| April | 24, 2021 | Raptors | 106 | Knicks | 105 |
| April | 25, 2021 | Bucks | 105 | Knicks | 110 |
| April | 26, 2021 | Knicks | 105 | Sonics | 94 |
| April | 28, 2021 | Knicks | 95 | Mavericks | 102 |
| April | 30, 2021 | Lakers | 111 | Knicks | 96 |
| May | 1, 2021 | Knicks | 117 | Suns | 114 |
| Post | 1, 2021 | Knicks | 82 | Celtics | 113 |
| Post | 2, 2021 | Knicks | 100 | Celtics | 106 |
| Post | 3, 2021 | Celtics | 90 | Knicks | 93 |
| Post | 4, 2021 | Celtics | 109 | Knicks | 94 |
| Post | 5, 2021 | Knicks | 95 | Celtics | 109 |
| Post | 6, 2021 | Celtics | | Knicks | |
| Post | 7, 2021 | Knicks | | Celtics | |