| month | day | visitor | score | home | score |
|---|
| November | 2, 2018 | Spurs | 109 | Jazz | 114 |
| November | 3, 2018 | Sonics | 117 | Spurs | 119 |
| November | 4, 2018 | Spurs | 117 | Lakers | 120 |
| November | 12, 2018 | Suns | 122 | Spurs | 117 |
| November | 14, 2018 | Grizzlies | 124 | Spurs | 122 |
| November | 17, 2018 | Spurs | 115 | Magic | 118 |
| November | 18, 2018 | Warriors | 100 | Spurs | 109 |
| November | 19, 2018 | Sonics | 107 | Spurs | 110 |
| November | 20, 2018 | Grizzlies | 110 | Spurs | 123 |
| November | 21, 2018 | Spurs | 99 | Lakers | 116 |
| November | 22, 2018 | Spurs | 125 | Lakers | 88 |
| November | 23, 2018 | 76ers | 128 | Spurs | 124 |
| November | 27, 2018 | Spurs | 125 | Suns | 120 |
| November | 28, 2018 | Thunder | 99 | Spurs | 106 |
| December | 1, 2018 | Spurs | 115 | Jazz | 100 |
| December | 2, 2018 | Spurs | 110 | Thunder | 132 |
| December | 5, 2018 | Pistons | 109 | Spurs | 115 |
| December | 8, 2018 | Thunder | 104 | Spurs | 114 |
| December | 11, 2018 | Spurs | 104 | Celtics | 108 |
| December | 14, 2018 | Suns | 84 | Spurs | 129 |
| December | 18, 2018 | Spurs | 117 | Suns | 102 |
| December | 19, 2018 | Spurs | 97 | Jazz | 112 |
| December | 21, 2018 | Warriors | 103 | Spurs | 118 |
| December | 23, 2018 | Rockets | 107 | Spurs | 81 |
| December | 25, 2018 | Spurs | 104 | Clippers | 109 |
| December | 26, 2018 | Cavaliers | 84 | Spurs | 114 |
| December | 28, 2018 | Spurs | 125 | Bucks | 114 |
| January | 2, 2019 | Spurs | 127 | Sonics | 123 |
| January | 3, 2019 | Spurs | 108 | Clippers | 112 |
| January | 5, 2019 | Bucks | 128 | Spurs | 104 |
| January | 6, 2019 | Spurs | 102 | Suns | 95 |
| January | 9, 2019 | Jazz | 109 | Spurs | 103 |
| January | 10, 2019 | Lakers | 99 | Spurs | 100 |
| January | 11, 2019 | Grizzlies | 97 | Spurs | 106 |
| January | 12, 2019 | Spurs | 99 | Sonics | 120 |
| January | 13, 2019 | Spurs | 105 | Sonics | 115 |
| January | 14, 2019 | Lakers | 101 | Spurs | 109 |
| January | 17, 2019 | Jazz | 88 | Spurs | 119 |
| January | 18, 2019 | Rockets | 82 | Spurs | 96 |
| January | 19, 2019 | Spurs | 111 | Grizzlies | 92 |
| January | 21, 2019 | Warriors | 108 | Spurs | 98 |
| January | 22, 2019 | Spurs | 104 | Pacers | 95 |
| January | 23, 2019 | Spurs | 108 | Warriors | 103 |
| January | 24, 2019 | Clippers | 120 | Spurs | 122 |
| January | 26, 2019 | Knicks | 108 | Spurs | 99 |
| January | 27, 2019 | Spurs | 119 | Bulls | 110 |
| January | 28, 2019 | Rockets | 96 | Spurs | 112 |
| January | 29, 2019 | Spurs | 112 | 76ers | 116 |
| February | 5, 2019 | Spurs | 100 | Jazz | 108 |
| February | 8, 2019 | Grizzlies | 99 | Spurs | 98 |
| February | 9, 2019 | Spurs | 113 | Thunder | 90 |
| February | 12, 2019 | Spurs | 89 | Rockets | 96 |
| February | 15, 2019 | Spurs | 102 | Knicks | 96 |
| February | 18, 2019 | Spurs | 105 | Jazz | 122 |
| February | 22, 2019 | Sonics | 140 | Spurs | 120 |
| February | 24, 2019 | Suns | 97 | Spurs | 127 |
| February | 25, 2019 | Celtics | 109 | Spurs | 112 |
| March | 2, 2019 | Clippers | 97 | Spurs | 112 |
| March | 5, 2019 | Spurs | 121 | Grizzlies | 104 |
| March | 6, 2019 | Spurs | 128 | Clippers | 95 |
| March | 8, 2019 | Spurs | 97 | Heat | 112 |
| March | 9, 2019 | Thunder | 109 | Spurs | 100 |
| March | 11, 2019 | Spurs | 92 | Rockets | 113 |
| March | 13, 2019 | Warriors | 107 | Spurs | 96 |
| March | 14, 2019 | Spurs | 117 | Lakers | 112 |
| March | 18, 2019 | Heat | 114 | Spurs | 119 |
| March | 21, 2019 | Thunder | 124 | Spurs | 129 |
| March | 23, 2019 | Spurs | 106 | Pistons | 115 |
| March | 24, 2019 | Spurs | 129 | Clippers | 107 |
| March | 25, 2019 | Spurs | 102 | Warriors | 103 |
| March | 26, 2019 | Bulls | 123 | Spurs | 114 |
| March | 31, 2019 | Spurs | 107 | Warriors | 99 |
| April | 4, 2019 | Spurs | 124 | Sonics | 123 |
| April | 5, 2019 | Suns | 86 | Spurs | 125 |
| April | 8, 2019 | Magic | 105 | Spurs | 122 |
| April | 9, 2019 | Rockets | 87 | Spurs | 104 |
| April | 10, 2019 | Pacers | 102 | Spurs | 101 |
| April | 12, 2019 | Spurs | 97 | Thunder | 113 |
| April | 13, 2019 | Rockets | 80 | Spurs | 86 |
| April | 15, 2019 | Spurs | 108 | Cavaliers | 115 |
| April | 17, 2019 | Lakers | 84 | Spurs | 102 |
| April | 18, 2019 | Spurs | 92 | Grizzlies | 106 |
| Post | 1, 2019 | Lakers | 89 | Spurs | 87 |
| Post | 2, 2019 | Lakers | 107 | Spurs | 126 |
| Post | 3, 2019 | Spurs | 102 | Lakers | 95 |
| Post | 4, 2019 | Spurs | 116 | Lakers | 96 |
| Post | 5, 2019 | Lakers | 77 | Spurs | 106 |
| Post | 6, 2019 | Spurs | | Lakers | |
| Post | 7, 2019 | Lakers | | Spurs | |
| Post | 8, 2019 | Spurs | 91 | Warriors | 96 |
| Post | 9, 2019 | Spurs | 99 | Warriors | 112 |
| Post | 10, 2019 | Warriors | 92 | Spurs | 103 |
| Post | 11, 2019 | Warriors | 84 | Spurs | 108 |
| Post | 12, 2019 | Spurs | 94 | Warriors | 91 |
| Post | 13, 2019 | Warriors | 101 | Spurs | 110 |
| Post | 14, 2019 | Spurs | | Warriors | |
| Post | 15, 2019 | Spurs | 110 | Sonics | 125 |
| Post | 16, 2019 | Spurs | 112 | Sonics | 126 |
| Post | 17, 2019 | Sonics | 89 | Spurs | 122 |
| Post | 18, 2019 | Sonics | 121 | Spurs | 127 |
| Post | 19, 2019 | Spurs | 103 | Sonics | 109 |
| Post | 20, 2019 | Sonics | 105 | Spurs | 111 |
| Post | 21, 2019 | Spurs | 110 | Sonics | 124 |