| month | day | visitor | score | home | score |
|---|
| November | 2, 2021 | Magic | 71 | 76ers | 75 |
| November | 3, 2021 | Magic | 93 | Pacers | 67 |
| November | 8, 2021 | Magic | 84 | Wizards | 122 |
| November | 13, 2021 | Knicks | 101 | Magic | 87 |
| November | 14, 2021 | Magic | 89 | 76ers | 92 |
| November | 15, 2021 | Magic | 101 | Knicks | 87 |
| November | 19, 2021 | Magic | 80 | Cavaliers | 85 |
| November | 20, 2021 | Magic | 77 | Bucks | 87 |
| November | 21, 2021 | Heat | 74 | Magic | 80 |
| November | 22, 2021 | Magic | 74 | Celtics | 104 |
| November | 29, 2021 | Bucks | 81 | Magic | 103 |
| November | 30, 2021 | Celtics | 85 | Magic | 77 |
| December | 3, 2021 | Magic | 98 | Pistons | 79 |
| December | 4, 2021 | Magic | 83 | Bulls | 86 |
| December | 7, 2021 | Magic | 70 | Nets | 101 |
| December | 8, 2021 | Magic | 76 | Heat | 73 |
| December | 13, 2021 | Knicks | 92 | Magic | 94 |
| December | 20, 2021 | Magic | 79 | Raptors | 96 |
| December | 22, 2021 | Bulls | 93 | Magic | 70 |
| December | 23, 2021 | Nets | 109 | Magic | 69 |
| December | 24, 2021 | Magic | 73 | Hawks | 76 |
| December | 25, 2021 | Pacers | 67 | Magic | 69 |
| December | 27, 2021 | Magic | 64 | Hornets | 106 |
| December | 29, 2021 | Cavaliers | 76 | Magic | 68 |
| December | 30, 2021 | Raptors | 94 | Magic | 91 |
| December | 31, 2021 | Hawks | 78 | Magic | 73 |
| January | 2, 2022 | Pistons | 85 | Magic | 82 |
| January | 3, 2022 | Hornets | 90 | Magic | 71 |
| January | 4, 2022 | Wizards | 67 | Magic | 75 |
| January | 9, 2022 | Heat | 81 | Magic | 82 |
| January | 10, 2022 | Magic | 85 | Celtics | 70 |
| January | 13, 2022 | 76ers | 77 | Magic | 76 |