| month | day | visitor | score | home | score |
|---|
| November | 3, 2022 | Grizzlies | 77 | Clippers | 118 |
| November | 6, 2022 | Spurs | 108 | Grizzlies | 103 |
| November | 8, 2022 | Sonics | 106 | Grizzlies | 110 |
| November | 11, 2022 | Warriors | 90 | Grizzlies | 102 |
| November | 12, 2022 | Pelicans | 90 | Grizzlies | 97 |
| November | 17, 2022 | Mavericks | 85 | Grizzlies | 89 |
| November | 19, 2022 | Grizzlies | 100 | Suns | 121 |
| November | 20, 2022 | Jazz | 94 | Grizzlies | 88 |
| November | 23, 2022 | Grizzlies | 91 | Pelicans | 102 |
| November | 24, 2022 | Grizzlies | 101 | Spurs | 99 |
| November | 30, 2022 | Grizzlies | 104 | Lakers | 130 |
| December | 1, 2022 | Grizzlies | 103 | Mavericks | 106 |
| December | 2, 2022 | Grizzlies | 120 | Blazers | 110 |
| December | 3, 2022 | Grizzlies | 99 | Sonics | 118 |
| December | 11, 2022 | Clippers | 114 | Grizzlies | 96 |
| December | 12, 2022 | Grizzlies | 80 | Jazz | 76 |
| December | 18, 2022 | Blazers | 94 | Grizzlies | 102 |
| December | 20, 2022 | Grizzlies | 74 | Rockets | 84 |
| December | 21, 2022 | Nuggets | 98 | Grizzlies | 94 |
| December | 22, 2022 | Lakers | 102 | Grizzlies | 119 |
| December | 24, 2022 | Grizzlies | 100 | Nuggets | 91 |
| December | 25, 2022 | Grizzlies | 90 | Warriors | 105 |
| December | 26, 2022 | Grizzlies | 87 | Kings | 111 |
| December | 27, 2022 | Grizzlies | 70 | Wolves | 87 |
| December | 31, 2022 | Kings | 98 | Grizzlies | 102 |
| January | 1, 2023 | Rockets | 86 | Grizzlies | 107 |
| January | 4, 2023 | Wolves | 75 | Grizzlies | 86 |
| January | 5, 2023 | Suns | 119 | Grizzlies | 124 |