| month | day | visitor | score | home | score |
|---|
| November | 4, 2005 | Grizzlies | 81 | Blazers | 80 |
| November | 5, 2005 | Grizzlies | 97 | Suns | 66 |
| November | 6, 2005 | Grizzlies | 94 | Blazers | 96 |
| November | 7, 2005 | Grizzlies | 96 | Bobcats | 119 |
| November | 8, 2005 | Grizzlies | 109 | Kings | 72 |
| November | 9, 2005 | Kings | 94 | Grizzlies | 101 |
| November | 10, 2005 | Grizzlies | 107 | Spurs | 91 |
| November | 11, 2005 | Grizzlies | 114 | Blazers | 95 |
| November | 17, 2005 | Bobcats | 82 | Grizzlies | 109 |
| November | 20, 2005 | Kings | 86 | Grizzlies | 104 |
| November | 23, 2005 | Grizzlies | 94 | Kings | 101 |
| November | 24, 2005 | Wizards | 104 | Grizzlies | 105 |
| December | 2, 2005 | Nets | 89 | Grizzlies | 115 |
| December | 5, 2005 | Suns | 103 | Grizzlies | 105 |
| December | 8, 2005 | Bucks | 90 | Grizzlies | 108 |
| December | 9, 2005 | Suns | 75 | Grizzlies | 111 |
| December | 19, 2005 | Grizzlies | 92 | Kings | 84 |
| December | 20, 2005 | Blazers | 97 | Grizzlies | 102 |
| December | 21, 2005 | Spurs | 98 | Grizzlies | 127 |
| December | 22, 2005 | Blazers | 113 | Grizzlies | 99 |
| December | 24, 2005 | Grizzlies | 100 | Suns | 72 |
| December | 27, 2005 | Grizzlies | 108 | Bucks | 96 |
| December | 28, 2005 | Blazers | 91 | Grizzlies | 97 |
| December | 29, 2005 | Blazers | 86 | Grizzlies | 105 |
| December | 31, 2005 | Kings | 101 | Grizzlies | 103 |
| January | 2, 2006 | Grizzlies | 95 | Nets | 101 |
| January | 6, 2006 | Grizzlies | 111 | Spurs | 101 |
| January | 7, 2006 | Suns | 101 | Grizzlies | 91 |
| January | 10, 2006 | Grizzlies | 75 | Wizards | 93 |
| January | 11, 2006 | Grizzlies | 89 | Spurs | 98 |
| January | 13, 2006 | Grizzlies | 85 | Suns | 99 |
| January | 15, 2006 | Spurs | 86 | Grizzlies | 95 |