| month | day | visitor | score | home | score |
|---|
| November | 4, 2005 | Cavaliers | 73 | Sonics | 116 |
| November | 5, 2005 | Kings | 112 | Sonics | 94 |
| November | 6, 2005 | Sonics | 115 | Nuggets | 94 |
| November | 7, 2005 | Bucks | 68 | Sonics | 92 |
| November | 8, 2005 | Hornets | 86 | Sonics | 99 |
| November | 10, 2005 | Sonics | 88 | Rockets | 75 |
| November | 14, 2005 | Jazz | 94 | Sonics | 101 |
| November | 15, 2005 | Sonics | 104 | Nuggets | 97 |
| November | 16, 2005 | Rockets | 90 | Sonics | 92 |
| November | 17, 2005 | Warriors | 86 | Sonics | 98 |
| November | 19, 2005 | Sonics | 109 | Bullets | 92 |
| November | 22, 2005 | Sonics | 105 | Nets | 68 |
| November | 23, 2005 | Kings | 117 | Sonics | 123 |
| November | 27, 2005 | Bullets | 84 | Sonics | 73 |
| November | 28, 2005 | Heat | 69 | Sonics | 66 |
| November | 29, 2005 | Sonics | 61 | Rockets | 77 |
| December | 2, 2005 | Sonics | 76 | Lakers | 93 |
| December | 3, 2005 | Mavericks | 73 | Sonics | 71 |
| December | 8, 2005 | Lakers | 93 | Sonics | 89 |
| December | 12, 2005 | 76ers | 114 | Sonics | 87 |
| December | 18, 2005 | Pacers | 87 | Sonics | 83 |
| December | 19, 2005 | Sonics | 79 | Spurs | 84 |
| December | 20, 2005 | Knicks | 112 | Sonics | 101 |
| December | 21, 2005 | Blazers | 93 | Sonics | 79 |
| December | 24, 2005 | Sonics | 59 | Suns | 79 |
| December | 25, 2005 | Raptors | 93 | Sonics | 92 |
| December | 27, 2005 | Lakers | 68 | Sonics | 83 |
| December | 29, 2005 | Sonics | | Warriors | |
| January | 3, 2006 | Sonics | | Pacers | |
| January | 4, 2006 | Sonics | | Hawks | |
| January | 5, 2006 | Suns | | Sonics | |
| January | 9, 2006 | Magic | | Sonics | |
| January | 10, 2006 | Sonics | | Jazz | |
| January | 12, 2006 | Sonics | | Lakers | |
| January | 14, 2006 | Sonics | | Suns | |
| January | 15, 2006 | Sonics | | Mavericks | |
| January | 16, 2006 | Grizzlies | | Sonics | |
| January | 17, 2006 | Lakers | | Sonics | |
| January | 19, 2006 | Sonics | | Grizzlies | |
| January | 20, 2006 | Celtics | | Sonics | |
| January | 21, 2006 | Sonics | | Clippers | |
| January | 22, 2006 | Blazers | | Sonics | |
| January | 23, 2006 | Sonics | | Knicks | |
| January | 25, 2006 | Sonics | | 76ers | |
| January | 29, 2006 | Blazers | | Sonics | |
| January | 31, 2006 | Wolves | | Sonics | |
| February | 1, 2006 | Clippers | | Sonics | |
| February | 2, 2006 | Sonics | | Wolves | |
| February | 4, 2006 | Clippers | | Sonics | |
| February | 10, 2006 | Sonics | | Blazers | |
| February | 12, 2006 | Sonics | | Magic | |
| February | 14, 2006 | Spurs | | Sonics | |
| February | 19, 2006 | Sonics | | Suns | |
| February | 20, 2006 | Sonics | | Jazz | |
| February | 23, 2006 | Sonics | | Hornets | |
| February | 24, 2006 | Sonics | | Kings | |
| February | 25, 2006 | Spurs | | Sonics | |
| March | 1, 2006 | Sonics | | Pistons | |
| March | 5, 2006 | Sonics | | Mavericks | |
| March | 6, 2006 | Grizzlies | | Sonics | |
| March | 8, 2006 | Hawks | | Sonics | |
| March | 16, 2006 | Sonics | | Bucks | |
| March | 17, 2006 | Clippers | | Sonics | |
| March | 19, 2006 | Kings | | Sonics | |
| March | 21, 2006 | Sonics | | Bulls | |
| March | 23, 2006 | Sonics | | Kings | |
| March | 25, 2006 | Pistons | | Sonics | |
| March | 28, 2006 | Bulls | | Sonics | |
| March | 30, 2006 | Sonics | | Warriors | |
| April | 2, 2006 | Sonics | | Raptors | |
| April | 3, 2006 | Sonics | | Warriors | |
| April | 4, 2006 | Sonics | | Cavaliers | |
| April | 8, 2006 | Sonics | | Celtics | |
| April | 11, 2006 | Warriors | | Sonics | |
| April | 12, 2006 | Sonics | | Blazers | |
| April | 13, 2006 | Nuggets | | Sonics | |
| April | 14, 2006 | Suns | | Sonics | |
| April | 18, 2006 | Nets | | Sonics | |
| April | 21, 2006 | Wolves | | Sonics | |
| April | 22, 2006 | Sonics | | Heat | |
| April | 24, 2006 | Sonics | | Clippers | |
| April | 25, 2006 | Sonics | | Spurs | |