| month | day | visitor | score | home | score |
|---|
| November | 3, 2022 | Warriors | 86 | Lakers | 127 |
| November | 4, 2022 | Warriors | 111 | Lakers | 131 |
| November | 5, 2022 | Clippers | 91 | Lakers | 125 |
| November | 6, 2022 | Lakers | 114 | Hawks | 140 |
| November | 7, 2022 | Lakers | 116 | Jazz | 125 |
| November | 8, 2022 | Bulls | 112 | Lakers | 119 |
| November | 10, 2022 | Lakers | 125 | Clippers | 131 |
| November | 12, 2022 | Lakers | 100 | Nuggets | 141 |
| November | 13, 2022 | Lakers | 93 | Spurs | 99 |
| November | 14, 2022 | Lakers | 126 | Wolves | 117 |
| November | 15, 2022 | Kings | 79 | Lakers | 98 |
| November | 20, 2022 | Lakers | 138 | Bucks | 136 |
| November | 22, 2022 | Suns | 104 | Lakers | 93 |
| November | 23, 2022 | Lakers | 92 | Heat | 109 |
| November | 25, 2022 | Sonics | 139 | Lakers | 89 |
| November | 26, 2022 | Lakers | 104 | Warriors | 95 |
| December | 1, 2022 | Pelicans | 128 | Lakers | 116 |
| December | 3, 2022 | Rockets | 103 | Lakers | 108 |
| December | 5, 2022 | Lakers | 101 | Kings | 90 |
| December | 7, 2022 | Clippers | 88 | Lakers | 112 |
| December | 8, 2022 | Kings | 88 | Lakers | 104 |
| December | 12, 2022 | Lakers | 121 | Raptors | 114 |
| December | 14, 2022 | Lakers | 123 | Clippers | 121 |
| December | 15, 2022 | Grizzlies | 95 | Lakers | 99 |
| December | 19, 2022 | Jazz | | Lakers | |
| December | 21, 2022 | Sonics | | Lakers | |
| December | 23, 2022 | Knicks | | Lakers | |
| December | 24, 2022 | Clippers | | Lakers | |
| December | 25, 2022 | Lakers | | Clippers | |
| December | 29, 2022 | Lakers | | Blazers | |
| December | 31, 2022 | Lakers | | Celtics | |
| January | 2, 2023 | Rockets | | Lakers | |
| January | 5, 2023 | Lakers | | Spurs | |
| January | 6, 2023 | Heat | | Lakers | |
| January | 7, 2023 | Kings | | Lakers | |
| January | 8, 2023 | Lakers | | Nets | |
| January | 14, 2023 | Lakers | | Mavericks | |
| January | 15, 2023 | Lakers | | Blazers | |
| January | 16, 2023 | Raptors | | Lakers | |
| January | 18, 2023 | Lakers | | Rockets | |
| January | 20, 2023 | Lakers | | Nuggets | |
| January | 21, 2023 | Lakers | | Kings | |
| January | 23, 2023 | Lakers | | Jazz | |
| January | 31, 2023 | Lakers | | Knicks | |
| February | 1, 2023 | Sonics | | Lakers | |
| February | 8, 2023 | Nuggets | | Lakers | |
| February | 9, 2023 | 76ers | | Lakers | |
| February | 14, 2023 | Blazers | | Lakers | |
| February | 15, 2023 | Lakers | | Warriors | |
| February | 18, 2023 | Jazz | | Lakers | |
| February | 20, 2023 | Lakers | | Rockets | |
| February | 21, 2023 | Nets | | Lakers | |
| February | 22, 2023 | Lakers | | Suns | |
| February | 25, 2023 | Celtics | | Lakers | |
| February | 28, 2023 | Lakers | | Pelicans | |
| March | 1, 2023 | Lakers | | 76ers | |
| March | 2, 2023 | Wolves | | Lakers | |
| March | 3, 2023 | Lakers | | Grizzlies | |
| March | 6, 2023 | Mavericks | | Lakers | |
| March | 9, 2023 | Spurs | | Lakers | |
| March | 10, 2023 | Warriors | | Lakers | |
| March | 12, 2023 | Spurs | | Lakers | |
| March | 16, 2023 | Bucks | | Lakers | |
| March | 18, 2023 | Suns | | Lakers | |
| March | 19, 2023 | Nuggets | | Lakers | |
| March | 23, 2023 | Lakers | | Sonics | |
| March | 26, 2023 | Lakers | | Kings | |
| March | 27, 2023 | Wolves | | Lakers | |
| March | 28, 2023 | Lakers | | Blazers | |
| March | 31, 2023 | Pacers | | Lakers | |
| April | 2, 2023 | Lakers | | Mavericks | |
| April | 8, 2023 | Lakers | | Bulls | |
| April | 10, 2023 | Lakers | | Pacers | |
| April | 11, 2023 | Lakers | | Warriors | |
| April | 15, 2023 | Blazers | | Lakers | |
| April | 16, 2023 | Lakers | | Sonics | |
| April | 17, 2023 | Hawks | | Lakers | |
| April | 18, 2023 | Lakers | | Suns | |
| April | 21, 2023 | Lakers | | Wolves | |
| April | 22, 2023 | Lakers | | Sonics | |
| April | 23, 2023 | Mavericks | | Lakers | |
| April | 25, 2023 | Blazers | | Lakers | |