| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Pelicans | 114 | Heat | 103 |
| November | 5, 2020 | Spurs | 110 | Heat | 105 |
| November | 7, 2020 | Celtics | 99 | Heat | 94 |
| November | 9, 2020 | Heat | 112 | Pelicans | 94 |
| November | 10, 2020 | Kings | 90 | Heat | 104 |
| November | 12, 2020 | Rockets | 116 | Heat | 87 |
| November | 16, 2020 | Nets | 95 | Heat | 100 |
| November | 18, 2020 | Heat | 96 | Nets | 103 |
| November | 22, 2020 | Grizzlies | 77 | Heat | 81 |
| November | 23, 2020 | Lakers | 99 | Heat | 82 |
| November | 27, 2020 | Heat | 85 | Knicks | 109 |
| November | 28, 2020 | Knicks | 108 | Heat | 102 |
| December | 1, 2020 | Raptors | 105 | Heat | 126 |
| December | 2, 2020 | Heat | 91 | 76ers | 108 |
| December | 3, 2020 | Pelicans | 95 | Heat | 98 |
| December | 5, 2020 | 76ers | 79 | Heat | 100 |
| December | 9, 2020 | Hawks | 131 | Heat | 114 |
| December | 10, 2020 | Heat | 84 | Knicks | 102 |
| December | 14, 2020 | Heat | 98 | Nets | 88 |
| December | 16, 2020 | Heat | 84 | Sonics | 124 |
| December | 18, 2020 | Heat | 127 | Blazers | 135 |
| December | 21, 2020 | Bulls | 92 | Heat | 89 |
| December | 24, 2020 | Blazers | 117 | Heat | 109 |
| December | 26, 2020 | Heat | 122 | Hawks | 129 |
| December | 28, 2020 | Heat | 111 | 76ers | 101 |
| January | 2, 2021 | Heat | 97 | 76ers | 88 |
| January | 3, 2021 | Heat | 76 | Bucks | 106 |
| January | 6, 2021 | Heat | 94 | Lakers | 70 |
| January | 9, 2021 | Heat | 102 | Bulls | 117 |
| January | 10, 2021 | Celtics | 110 | Heat | 101 |
| January | 11, 2021 | Jazz | 91 | Heat | 93 |
| January | 12, 2021 | Heat | 89 | Rockets | 116 |
| January | 17, 2021 | Heat | 98 | Nets | 92 |
| January | 18, 2021 | Heat | 95 | Raptors | 131 |
| January | 19, 2021 | Heat | 107 | Clippers | 96 |
| January | 20, 2021 | Heat | 130 | Warriors | 138 |
| January | 21, 2021 | Bucks | 97 | Heat | 106 |
| January | 22, 2021 | Grizzlies | 92 | Heat | 67 |
| January | 26, 2021 | Heat | 106 | Knicks | 109 |
| February | 2, 2021 | Heat | | Celtics | |
| February | 4, 2021 | Heat | | Spurs | |
| February | 8, 2021 | Heat | | Mavericks | |
| February | 9, 2021 | Heat | | Pacers | |
| February | 10, 2021 | Clippers | | Heat | |
| February | 12, 2021 | Heat | | Kings | |
| February | 13, 2021 | Warriors | | Heat | |
| February | 15, 2021 | Heat | | Pacers | |
| February | 16, 2021 | Bucks | | Heat | |
| February | 18, 2021 | Heat | | Hawks | |
| February | 20, 2021 | Heat | | Bucks | |
| February | 23, 2021 | Pacers | | Heat | |
| February | 25, 2021 | Nuggets | | Heat | |
| February | 26, 2021 | Heat | | Pelicans | |
| February | 28, 2021 | Nets | | Heat | |
| March | 4, 2021 | Heat | | Suns | |
| March | 5, 2021 | Heat | | Jazz | |
| March | 7, 2021 | Hawks | | Heat | |
| March | 8, 2021 | Sonics | | Heat | |
| March | 14, 2021 | Heat | | Nets | |
| March | 18, 2021 | Hawks | | Heat | |
| March | 19, 2021 | Heat | | Celtics | |
| March | 20, 2021 | Heat | | Bulls | |
| March | 22, 2021 | Raptors | | Heat | |
| March | 26, 2021 | Heat | | Raptors | |
| March | 28, 2021 | Pelicans | | Heat | |
| March | 29, 2021 | Suns | | Heat | |
| April | 2, 2021 | 76ers | | Heat | |
| April | 4, 2021 | Bulls | | Heat | |
| April | 5, 2021 | Heat | | Wolves | |
| April | 6, 2021 | 76ers | | Heat | |
| April | 7, 2021 | Heat | | Knicks | |
| April | 8, 2021 | Heat | | Pelicans | |
| April | 10, 2021 | Celtics | | Heat | |
| April | 11, 2021 | Pacers | | Heat | |
| April | 12, 2021 | Heat | | Nuggets | |
| April | 14, 2021 | Heat | | Grizzlies | |
| April | 15, 2021 | Wolves | | Heat | |
| April | 18, 2021 | Celtics | | Heat | |
| April | 19, 2021 | Grizzlies | | Heat | |
| April | 20, 2021 | Heat | | Grizzlies | |
| April | 21, 2021 | Mavericks | | Heat | |
| April | 22, 2021 | Knicks | | Heat | |