| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Raptors | 105 | Mavericks | 120 |
| November | 3, 2020 | Hawks | 111 | Raptors | 142 |
| November | 5, 2020 | Nuggets | 131 | Raptors | 137 |
| November | 6, 2020 | Celtics | 113 | Raptors | 120 |
| November | 8, 2020 | Sonics | 95 | Raptors | 119 |
| November | 9, 2020 | Raptors | 101 | Hawks | 102 |
| November | 11, 2020 | Raptors | 123 | Nets | 97 |
| November | 13, 2020 | Raptors | 121 | Pacers | 101 |
| November | 14, 2020 | Raptors | 111 | Celtics | 107 |
| November | 16, 2020 | Raptors | 126 | Pacers | 118 |
| November | 17, 2020 | Raptors | 109 | Knicks | 132 |
| November | 19, 2020 | Raptors | 133 | Pacers | 132 |
| November | 20, 2020 | Raptors | 123 | Bulls | 92 |
| November | 21, 2020 | Wolves | 102 | Raptors | 116 |
| November | 23, 2020 | Raptors | 123 | Warriors | 127 |
| November | 24, 2020 | Raptors | 147 | Celtics | 125 |
| November | 27, 2020 | Raptors | 125 | Rockets | 120 |
| November | 29, 2020 | Jazz | 107 | Raptors | 146 |
| December | 1, 2020 | Raptors | 132 | Heat | 118 |
| December | 4, 2020 | Raptors | 141 | Hawks | 116 |
| December | 8, 2020 | Warriors | 128 | Raptors | 143 |
| December | 9, 2020 | Bulls | 129 | Raptors | 138 |
| December | 10, 2020 | Raptors | 121 | Blazers | 101 |
| December | 12, 2020 | Lakers | 140 | Raptors | 101 |
| December | 14, 2020 | Knicks | 111 | Raptors | 121 |
| December | 18, 2020 | Raptors | 97 | Grizzlies | 113 |
| December | 19, 2020 | Hawks | 108 | Raptors | 132 |
| December | 21, 2020 | Raptors | 96 | 76ers | 103 |
| December | 22, 2020 | Bucks | 127 | Raptors | 119 |
| December | 23, 2020 | Raptors | 109 | Wolves | 143 |
| December | 24, 2020 | Grizzlies | 109 | Raptors | 130 |
| December | 26, 2020 | Raptors | 116 | Knicks | 120 |
| December | 27, 2020 | Raptors | 128 | Bucks | 119 |
| December | 28, 2020 | Clippers | 102 | Raptors | 131 |
| January | 4, 2021 | Knicks | 123 | Raptors | 120 |
| January | 7, 2021 | Nets | 103 | Raptors | 112 |
| January | 12, 2021 | Raptors | 97 | Bucks | 113 |
| January | 14, 2021 | Raptors | 126 | Grizzlies | 106 |
| January | 16, 2021 | Raptors | 110 | Lakers | 115 |
| January | 18, 2021 | Heat | 98 | Raptors | 124 |
| January | 22, 2021 | Pacers | 102 | Raptors | 136 |
| January | 26, 2021 | Kings | 82 | Raptors | 121 |
| January | 29, 2021 | Raptors | 111 | Clippers | 108 |
| January | 31, 2021 | Raptors | 101 | Nets | 107 |
| February | 1, 2021 | Rockets | 129 | Raptors | 124 |
| February | 2, 2021 | Pelicans | 110 | Raptors | 137 |
| February | 4, 2021 | Raptors | 122 | Hawks | 107 |
| February | 8, 2021 | 76ers | 83 | Raptors | 123 |
| February | 10, 2021 | Nets | 87 | Raptors | 121 |
| February | 11, 2021 | Raptors | 118 | 76ers | 96 |
| February | 12, 2021 | Bulls | 94 | Raptors | 115 |
| February | 14, 2021 | Grizzlies | 93 | Raptors | 107 |
| February | 15, 2021 | Mavericks | 113 | Raptors | 122 |
| February | 16, 2021 | Suns | 115 | Raptors | 154 |
| February | 19, 2021 | Celtics | 117 | Raptors | 128 |
| February | 20, 2021 | Hawks | 99 | Raptors | 117 |
| February | 23, 2021 | Raptors | 104 | Nuggets | 133 |
| February | 24, 2021 | Raptors | 107 | Kings | 96 |
| March | 1, 2021 | Pacers | 128 | Raptors | 110 |
| March | 2, 2021 | Raptors | 113 | Suns | 111 |
| March | 4, 2021 | Raptors | 117 | Bulls | 124 |
| March | 5, 2021 | Pelicans | 111 | Raptors | 129 |
| March | 6, 2021 | Raptors | 121 | Sonics | 124 |
| March | 9, 2021 | Bucks | 105 | Raptors | 111 |
| March | 10, 2021 | Pacers | 117 | Raptors | 127 |
| March | 13, 2021 | Blazers | 112 | Raptors | 118 |
| March | 14, 2021 | Raptors | 105 | Grizzlies | 79 |
| March | 16, 2021 | Raptors | 106 | 76ers | 98 |
| March | 17, 2021 | Raptors | 104 | Jazz | 107 |
| March | 18, 2021 | Grizzlies | 88 | Raptors | 96 |
| March | 22, 2021 | Raptors | 97 | Heat | 79 |
| March | 24, 2021 | Pacers | 113 | Raptors | 96 |
| March | 25, 2021 | Bucks | 120 | Raptors | 140 |
| March | 26, 2021 | Heat | 99 | Raptors | 110 |
| March | 31, 2021 | 76ers | 98 | Raptors | 112 |
| April | 4, 2021 | Raptors | 121 | Spurs | 103 |
| April | 5, 2021 | Raptors | 108 | Pelicans | 136 |
| April | 14, 2021 | Spurs | 109 | Raptors | 128 |
| April | 15, 2021 | Raptors | 121 | Bulls | 99 |
| April | 20, 2021 | Raptors | 138 | Pelicans | 132 |
| April | 23, 2021 | Raptors | 105 | Bucks | 127 |
| April | 24, 2021 | Bulls | 105 | Raptors | 140 |
| Post | 1, 2021 | Pacers | 100 | Raptors | 123 |
| Post | 2, 2021 | Pacers | 124 | Raptors | 135 |
| Post | 3, 2021 | Raptors | 124 | Pacers | 128 |
| Post | 4, 2021 | Raptors | 131 | Pacers | 126 |
| Post | 5, 2021 | Pacers | 109 | Raptors | 108 |
| Post | 6, 2021 | Raptors | 146 | Pacers | 114 |
| Post | 7, 2021 | Pacers | | Raptors | |
| Post | 8, 2021 | Bucks | 111 | Raptors | 125 |
| Post | 9, 2021 | Bucks | 98 | Raptors | 118 |
| Post | 10, 2021 | Raptors | 126 | Bucks | 125 |
| Post | 11, 2021 | Raptors | 113 | Bucks | 122 |
| Post | 12, 2021 | Bucks | 115 | Raptors | 133 |
| Post | 13, 2021 | Raptors | | Bucks | |
| Post | 14, 2021 | Bucks | | Raptors | |
| Post | 15, 2021 | Raptors | 123 | Pelicans | 125 |
| Post | 16, 2021 | Raptors | 118 | Pelicans | 133 |
| Post | 17, 2021 | Pelicans | 145 | Raptors | 141 |
| Post | 18, 2021 | Pelicans | 121 | Raptors | 114 |
| Post | 19, 2021 | Raptors | | Pelicans | |
| Post | 20, 2021 | Pelicans | | Raptors | |
| Post | 21, 2021 | Raptors | | Pelicans | |