| month | day | visitor | score | home | score |
|---|
| November | 2, 2021 | Bulls | 69 | Wizards | 86 |
| November | 4, 2021 | Wizards | 107 | Raptors | 99 |
| November | 7, 2021 | Pistons | 62 | Wizards | 95 |
| November | 8, 2021 | Magic | 84 | Wizards | 122 |
| November | 16, 2021 | Wizards | 83 | Bulls | 94 |
| November | 17, 2021 | Hawks | 93 | Wizards | 111 |
| November | 18, 2021 | Cavaliers | 72 | Wizards | 104 |
| November | 22, 2021 | Wizards | 94 | Bulls | 68 |
| November | 23, 2021 | Wizards | 86 | Pacers | 60 |
| November | 26, 2021 | Celtics | 62 | Wizards | 67 |
| November | 27, 2021 | Wizards | 68 | 76ers | 93 |
| November | 28, 2021 | Raptors | 84 | Wizards | 90 |
| December | 1, 2021 | Hornets | 76 | Wizards | 78 |
| December | 2, 2021 | Wizards | 78 | Knicks | 88 |
| December | 3, 2021 | Wizards | 88 | Bucks | 81 |
| December | 15, 2021 | Wizards | 75 | Bucks | 90 |
| December | 16, 2021 | Nets | 78 | Wizards | 72 |
| December | 18, 2021 | Wizards | 61 | Cavaliers | 65 |
| December | 19, 2021 | Wizards | 63 | Pistons | 70 |
| December | 20, 2021 | Wizards | 57 | Hornets | 96 |
| December | 25, 2021 | Wizards | 72 | Celtics | 63 |
| December | 28, 2021 | Pacers | 56 | Wizards | 60 |
| December | 29, 2021 | Heat | 89 | Wizards | 80 |
| December | 30, 2021 | Nets | 82 | Wizards | 79 |
| December | 31, 2021 | Wizards | 65 | Heat | 75 |
| January | 1, 2022 | 76ers | 57 | Wizards | 74 |
| January | 2, 2022 | Wizards | 68 | Nets | 87 |
| January | 4, 2022 | Wizards | 67 | Magic | 75 |
| January | 5, 2022 | Knicks | 80 | Wizards | 87 |
| January | 8, 2022 | Bucks | 87 | Wizards | 89 |
| January | 11, 2022 | Wizards | 89 | Hawks | 71 |
| January | 13, 2022 | Cavaliers | 76 | Wizards | 77 |