| month | day | visitor | score | home | score |
|---|
| November | 4, 2021 | Suns | 82 | Clippers | 113 |
| November | 5, 2021 | Sonics | 125 | Suns | 106 |
| November | 6, 2021 | Suns | 95 | Kings | 116 |
| November | 8, 2021 | Suns | 90 | Pelicans | 126 |
| November | 11, 2021 | Suns | 90 | Kings | 105 |
| November | 12, 2021 | Suns | 84 | Warriors | 96 |
| November | 14, 2021 | Suns | 70 | Rockets | 94 |
| November | 15, 2021 | Sonics | 108 | Suns | 115 |
| November | 20, 2021 | Pelicans | 112 | Suns | 103 |
| November | 22, 2021 | Spurs | 83 | Suns | 90 |
| November | 23, 2021 | Suns | 112 | Sonics | 101 |
| November | 26, 2021 | Suns | 103 | Grizzlies | 89 |
| November | 30, 2021 | Suns | 85 | Mavericks | 83 |
| December | 4, 2021 | Wolves | 87 | Suns | 80 |
| December | 5, 2021 | Kings | 79 | Suns | 88 |
| December | 6, 2021 | Suns | 81 | Jazz | 113 |
| December | 8, 2021 | Clippers | 105 | Suns | 118 |
| December | 13, 2021 | Suns | 99 | Spurs | 88 |
| December | 16, 2021 | Nuggets | 93 | Suns | 96 |
| December | 20, 2021 | Suns | 101 | Wolves | 94 |
| December | 21, 2021 | Grizzlies | 107 | Suns | 112 |
| December | 22, 2021 | Rockets | 80 | Suns | 92 |
| December | 23, 2021 | Suns | 91 | Lakers | 89 |
| December | 24, 2021 | Lakers | 76 | Suns | 106 |
| December | 27, 2021 | Lakers | 103 | Suns | 107 |
| January | 1, 2022 | Blazers | 86 | Suns | 111 |
| January | 2, 2022 | Jazz | 73 | Suns | 81 |
| January | 5, 2022 | Suns | 63 | Warriors | 100 |
| January | 7, 2022 | Warriors | 85 | Suns | 86 |
| January | 8, 2022 | Mavericks | 93 | Suns | 84 |
| January | 9, 2022 | Suns | 123 | Nuggets | 121 |
| January | 13, 2022 | Suns | 85 | Blazers | 92 |