| month | day | visitor | score | home | score |
|---|
| November | 2, 2021 | Bucks | 79 | Hornets | 94 |
| November | 3, 2021 | Bucks | 92 | Pistons | 60 |
| November | 8, 2021 | Bucks | 94 | Pacers | 64 |
| November | 12, 2021 | Pacers | 77 | Bucks | 95 |
| November | 13, 2021 | Bucks | 86 | Celtics | 90 |
| November | 16, 2021 | Pistons | 75 | Bucks | 86 |
| November | 17, 2021 | Cavaliers | 68 | Bucks | 82 |
| November | 18, 2021 | Hornets | 74 | Bucks | 91 |
| November | 19, 2021 | Bucks | 79 | Bulls | 70 |
| November | 20, 2021 | Magic | 77 | Bucks | 87 |
| November | 22, 2021 | Knicks | 94 | Bucks | 100 |
| November | 24, 2021 | Bulls | 106 | Bucks | 101 |
| November | 29, 2021 | Bucks | 81 | Magic | 103 |
| November | 30, 2021 | Heat | 84 | Bucks | 78 |
| December | 3, 2021 | Wizards | 88 | Bucks | 81 |
| December | 5, 2021 | Nets | 82 | Bucks | 90 |
| December | 14, 2021 | Bucks | 82 | Cavaliers | 81 |
| December | 15, 2021 | Wizards | 75 | Bucks | 90 |
| December | 16, 2021 | Raptors | 101 | Bucks | 112 |
| December | 18, 2021 | Celtics | 61 | Bucks | 72 |
| December | 21, 2021 | Bucks | 79 | Nets | 100 |
| December | 22, 2021 | Bucks | 84 | Knicks | 86 |
| December | 23, 2021 | Hawks | 94 | Bucks | 62 |
| December | 30, 2021 | Bucks | 96 | Cavaliers | 93 |
| January | 2, 2022 | Bucks | 51 | Heat | 94 |
| January | 4, 2022 | Bucks | 71 | Bulls | 91 |
| January | 6, 2022 | Nets | 79 | Bucks | 78 |
| January | 7, 2022 | Bucks | 72 | 76ers | 82 |
| January | 8, 2022 | Bucks | 87 | Wizards | 89 |
| January | 9, 2022 | Bucks | 98 | Hawks | 100 |
| January | 10, 2022 | 76ers | 82 | Bucks | 103 |
| January | 12, 2022 | Bucks | 86 | Raptors | 107 |