| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Raptors | 84 | Warriors | 105 |
| November | 4, 2020 | Clippers | 108 | Raptors | 94 |
| November | 6, 2020 | Pistons | 76 | Raptors | 94 |
| November | 9, 2020 | Mavericks | 77 | Raptors | 109 |
| November | 13, 2020 | Raptors | 100 | Hawks | 91 |
| November | 15, 2020 | Raptors | 75 | Celtics | 117 |
| November | 16, 2020 | Raptors | 100 | Mavericks | 94 |
| November | 17, 2020 | Lakers | 111 | Raptors | 93 |
| November | 20, 2020 | Raptors | 96 | Clippers | 101 |
| November | 21, 2020 | Raptors | 89 | Bucks | 111 |
| November | 23, 2020 | Kings | 97 | Raptors | 93 |
| November | 24, 2020 | Grizzlies | 91 | Raptors | 110 |
| November | 29, 2020 | Nets | 100 | Raptors | 99 |
| December | 2, 2020 | Hawks | 79 | Raptors | 102 |
| December | 3, 2020 | Raptors | 100 | Hawks | 75 |
| December | 4, 2020 | Knicks | 102 | Raptors | 93 |
| December | 5, 2020 | Raptors | 90 | Heat | 103 |
| December | 11, 2020 | Celtics | 103 | Raptors | 113 |
| December | 12, 2020 | Raptors | 89 | Blazers | 104 |
| December | 16, 2020 | Jazz | 99 | Raptors | 96 |
| December | 19, 2020 | Suns | 86 | Raptors | 92 |
| December | 21, 2020 | Knicks | 87 | Raptors | 116 |
| December | 24, 2020 | Pacers | 85 | Raptors | 79 |
| December | 25, 2020 | Raptors | 99 | Sonics | 136 |
| December | 26, 2020 | Cavaliers | 90 | Raptors | 108 |
| December | 27, 2020 | Raptors | 86 | Pelicans | 124 |
| December | 29, 2020 | Raptors | 94 | Wizards | 102 |
| December | 30, 2020 | Raptors | 84 | Wizards | 101 |
| January | 11, 2021 | Raptors | 91 | Bulls | 93 |
| January | 12, 2021 | Hawks | 76 | Raptors | 108 |
| January | 13, 2021 | Raptors | 99 | Bucks | 115 |
| January | 15, 2021 | Raptors | 98 | Heat | 101 |
| January | 16, 2021 | Wizards | 115 | Raptors | 119 |
| January | 21, 2021 | Raptors | 96 | Jazz | 93 |
| January | 22, 2021 | Raptors | 91 | Bobcats | 118 |
| January | 23, 2021 | Raptors | 113 | Cavaliers | 99 |
| January | 26, 2021 | Raptors | 97 | Suns | 98 |
| January | 27, 2021 | Raptors | 87 | Bulls | 108 |
| February | 2, 2021 | Raptors | 81 | Pistons | 91 |
| February | 6, 2021 | Raptors | 108 | Nets | 102 |
| February | 11, 2021 | Sonics | 113 | Raptors | 109 |
| February | 12, 2021 | Bucks | 102 | Raptors | 99 |
| February | 15, 2021 | Raptors | 79 | Spurs | 74 |
| February | 17, 2021 | Raptors | 93 | Rockets | 114 |
| February | 18, 2021 | Bulls | 106 | Raptors | 76 |
| February | 19, 2021 | Raptors | 78 | Magic | 104 |
| February | 20, 2021 | Bobcats | 110 | Raptors | 98 |
| February | 22, 2021 | Cavaliers | 66 | Raptors | 109 |
| February | 25, 2021 | Warriors | 74 | Raptors | 83 |
| February | 26, 2021 | Rockets | 93 | Raptors | 99 |
| February | 27, 2021 | Raptors | 82 | Wolves | 95 |
| March | 1, 2021 | Heat | 74 | Raptors | 94 |
| March | 3, 2021 | Nuggets | 109 | Raptors | 132 |
| March | 4, 2021 | Raptors | 100 | Bobcats | 97 |
| March | 5, 2021 | Heat | 100 | Raptors | 94 |
| March | 6, 2021 | Raptors | 73 | Grizzlies | 81 |
| March | 8, 2021 | Wizards | 98 | Raptors | 104 |
| March | 9, 2021 | Raptors | 110 | Cavaliers | 92 |
| March | 10, 2021 | Nets | 86 | Raptors | 80 |
| March | 12, 2021 | Bulls | 94 | Raptors | 118 |
| March | 13, 2021 | Magic | 106 | Raptors | 102 |
| March | 14, 2021 | Blazers | 106 | Raptors | 95 |
| March | 16, 2021 | Pistons | 86 | Raptors | 97 |
| March | 17, 2021 | Magic | 98 | Raptors | 94 |
| March | 18, 2021 | Raptors | 93 | Magic | 90 |
| March | 19, 2021 | Raptors | 71 | Celtics | 102 |
| March | 21, 2021 | Bucks | 110 | Raptors | 88 |
| March | 22, 2021 | Pacers | 81 | Raptors | 61 |
| March | 23, 2021 | Raptors | 79 | Nuggets | 99 |
| March | 26, 2021 | Spurs | 103 | Raptors | 98 |
| March | 30, 2021 | Raptors | 116 | Kings | 110 |
| April | 1, 2021 | Raptors | 67 | 76ers | 85 |
| April | 3, 2021 | Wolves | 105 | Raptors | 101 |
| April | 8, 2021 | Raptors | 87 | Nets | 68 |
| April | 10, 2021 | 76ers | 91 | Raptors | 103 |
| April | 11, 2021 | Raptors | 95 | 76ers | 64 |
| April | 12, 2021 | Raptors | 99 | Knicks | 69 |
| April | 13, 2021 | Celtics | 93 | Raptors | 92 |
| April | 22, 2021 | Pelicans | 109 | Raptors | 100 |
| April | 24, 2021 | Raptors | 106 | Knicks | 105 |
| April | 29, 2021 | Raptors | 90 | Pacers | 84 |
| May | 1, 2021 | Raptors | 107 | Lakers | 126 |