| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | 76ers | 70 | Mavericks | 83 |
| November | 6, 2020 | Mavericks | 80 | Jazz | 97 |
| November | 8, 2020 | Mavericks | 60 | Warriors | 90 |
| November | 9, 2020 | Mavericks | 77 | Raptors | 109 |
| November | 12, 2020 | Mavericks | 70 | Pelicans | 106 |
| November | 13, 2020 | Magic | 68 | Mavericks | 84 |
| November | 14, 2020 | Mavericks | 81 | Warriors | 73 |
| November | 15, 2020 | Warriors | 72 | Mavericks | 80 |
| November | 16, 2020 | Raptors | 100 | Mavericks | 94 |
| November | 21, 2020 | Warriors | 75 | Mavericks | 87 |
| November | 23, 2020 | Mavericks | 92 | Hawks | 67 |
| November | 27, 2020 | Mavericks | 90 | Nuggets | 72 |
| November | 29, 2020 | Mavericks | 78 | Blazers | 65 |
| December | 4, 2020 | Pelicans | 106 | Mavericks | 90 |
| December | 5, 2020 | Blazers | 76 | Mavericks | 69 |
| December | 6, 2020 | Mavericks | 98 | Kings | 106 |
| December | 8, 2020 | Mavericks | 64 | Spurs | 66 |
| December | 10, 2020 | Mavericks | 99 | Kings | 111 |
| December | 13, 2020 | Mavericks | 79 | Suns | 89 |
| December | 15, 2020 | Jazz | 96 | Mavericks | 66 |
| December | 16, 2020 | Hawks | 82 | Mavericks | 68 |
| December | 17, 2020 | Mavericks | 76 | Lakers | 104 |
| December | 18, 2020 | Mavericks | 89 | Magic | 84 |
| December | 22, 2020 | Mavericks | 81 | Sonics | 103 |
| December | 23, 2020 | Mavericks | 87 | Suns | 103 |
| December | 28, 2020 | Sonics | 98 | Mavericks | 69 |
| December | 30, 2020 | Pelicans | 109 | Mavericks | 74 |
| January | 2, 2021 | Grizzlies | 63 | Mavericks | 95 |
| January | 3, 2021 | Mavericks | 63 | Blazers | 85 |
| January | 6, 2021 | Mavericks | 80 | Nuggets | 106 |
| January | 7, 2021 | Pistons | 73 | Mavericks | 63 |
| January | 8, 2021 | Mavericks | 85 | Bobcats | 84 |
| January | 15, 2021 | Lakers | 93 | Mavericks | 88 |
| January | 16, 2021 | Mavericks | 61 | Bucks | 95 |
| January | 18, 2021 | Suns | 96 | Mavericks | 99 |
| January | 19, 2021 | Mavericks | 89 | Clippers | 96 |
| January | 22, 2021 | Mavericks | 72 | Cavaliers | 82 |
| January | 24, 2021 | Wizards | 87 | Mavericks | 75 |
| January | 27, 2021 | Mavericks | 70 | Pistons | 71 |
| January | 28, 2021 | Mavericks | 76 | Celtics | 94 |
| January | 29, 2021 | Mavericks | 58 | Heat | 94 |
| February | 1, 2021 | Mavericks | 80 | Nets | 100 |
| February | 5, 2021 | Mavericks | 93 | Pacers | 88 |
| February | 7, 2021 | Wolves | 77 | Mavericks | 86 |
| February | 12, 2021 | Clippers | 89 | Mavericks | 93 |
| February | 15, 2021 | Mavericks | 69 | Sonics | 97 |
| February | 16, 2021 | Celtics | 107 | Mavericks | 62 |
| February | 20, 2021 | Heat | 73 | Mavericks | 99 |
| February | 24, 2021 | Mavericks | 82 | Wizards | 89 |
| February | 25, 2021 | Spurs | 85 | Mavericks | 83 |
| February | 27, 2021 | Mavericks | 79 | Clippers | 90 |
| February | 28, 2021 | Mavericks | 68 | Rockets | 85 |
| March | 1, 2021 | Mavericks | 56 | Wolves | 100 |
| March | 2, 2021 | Bucks | 90 | Mavericks | 74 |
| March | 3, 2021 | Jazz | 70 | Mavericks | 71 |
| March | 4, 2021 | Mavericks | 82 | Wolves | 88 |
| March | 6, 2021 | Nets | 91 | Mavericks | 87 |
| March | 8, 2021 | Sonics | 95 | Mavericks | 97 |
| March | 9, 2021 | Mavericks | 83 | Grizzlies | 89 |
| March | 10, 2021 | Kings | 99 | Mavericks | 74 |
| March | 11, 2021 | Mavericks | 76 | Lakers | 99 |
| March | 12, 2021 | Lakers | 95 | Mavericks | 70 |
| March | 13, 2021 | Nuggets | 95 | Mavericks | 57 |
| March | 17, 2021 | Mavericks | 61 | Rockets | 93 |
| March | 18, 2021 | Pacers | 82 | Mavericks | 86 |
| March | 19, 2021 | Mavericks | 71 | Spurs | 82 |
| March | 21, 2021 | Mavericks | 69 | Pelicans | 103 |
| March | 23, 2021 | Mavericks | 70 | Bulls | 105 |
| March | 26, 2021 | Blazers | 78 | Mavericks | 70 |
| March | 28, 2021 | Rockets | 71 | Mavericks | 69 |
| April | 2, 2021 | Mavericks | 74 | 76ers | 71 |
| April | 5, 2021 | Cavaliers | 73 | Mavericks | 85 |
| April | 6, 2021 | Suns | 112 | Mavericks | 100 |
| April | 8, 2021 | Wolves | 76 | Mavericks | 90 |
| April | 11, 2021 | Bobcats | 65 | Mavericks | 90 |
| April | 13, 2021 | Clippers | 96 | Mavericks | 94 |
| April | 18, 2021 | Kings | 91 | Mavericks | 95 |
| April | 20, 2021 | Spurs | 68 | Mavericks | 75 |
| April | 22, 2021 | Mavericks | 97 | Knicks | 101 |
| April | 23, 2021 | Grizzlies | 83 | Mavericks | 70 |
| April | 28, 2021 | Knicks | 95 | Mavericks | 102 |
| April | 29, 2021 | Bulls | 94 | Mavericks | 70 |