| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Blazers | 78 | Cavaliers | 85 |
| November | 4, 2020 | Blazers | 81 | Spurs | 84 |
| November | 7, 2020 | Blazers | 74 | Bucks | 105 |
| November | 9, 2020 | Lakers | 87 | Blazers | 104 |
| November | 10, 2020 | Blazers | 67 | Heat | 82 |
| November | 12, 2020 | Blazers | 78 | Nuggets | 111 |
| November | 13, 2020 | Suns | 73 | Blazers | 76 |
| November | 14, 2020 | Blazers | 88 | Jazz | 95 |
| November | 16, 2020 | Blazers | 91 | Hawks | 67 |
| November | 19, 2020 | Magic | 77 | Blazers | 72 |
| November | 21, 2020 | Blazers | 88 | Jazz | 110 |
| November | 23, 2020 | Blazers | 72 | Suns | 81 |
| November | 26, 2020 | Rockets | 86 | Blazers | 87 |
| November | 27, 2020 | Nets | 91 | Blazers | 94 |
| November | 28, 2020 | Blazers | 83 | Rockets | 96 |
| November | 29, 2020 | Mavericks | 78 | Blazers | 65 |
| December | 2, 2020 | Pelicans | 103 | Blazers | 111 |
| December | 5, 2020 | Blazers | 76 | Mavericks | 69 |
| December | 7, 2020 | Blazers | 84 | Warriors | 69 |
| December | 9, 2020 | Spurs | 83 | Blazers | 75 |
| December | 11, 2020 | Blazers | 88 | Nuggets | 86 |
| December | 12, 2020 | Raptors | 89 | Blazers | 104 |
| December | 14, 2020 | Grizzlies | 84 | Blazers | 91 |
| December | 17, 2020 | Rockets | 69 | Blazers | 92 |
| December | 21, 2020 | Warriors | 75 | Blazers | 81 |
| December | 22, 2020 | Pelicans | 137 | Blazers | 96 |
| December | 24, 2020 | Kings | 99 | Blazers | 96 |
| December | 31, 2020 | Jazz | 76 | Blazers | 85 |
| January | 1, 2021 | Bulls | 97 | Blazers | 89 |
| January | 3, 2021 | Mavericks | 63 | Blazers | 85 |
| January | 6, 2021 | Blazers | 90 | Clippers | 112 |
| January | 10, 2021 | Blazers | 98 | Lakers | 103 |
| January | 13, 2021 | Wolves | 89 | Blazers | 91 |
| January | 16, 2021 | 76ers | 72 | Blazers | 101 |
| January | 19, 2021 | Blazers | 87 | Grizzlies | 62 |
| January | 20, 2021 | Wolves | 84 | Blazers | 81 |
| January | 21, 2021 | Blazers | 79 | Sonics | 82 |
| January | 22, 2021 | Sonics | 87 | Blazers | 92 |
| January | 23, 2021 | Sonics | 110 | Blazers | 106 |
| January | 24, 2021 | Spurs | 63 | Blazers | 75 |
| January | 28, 2021 | Blazers | 105 | Lakers | 102 |
| January | 30, 2021 | Heat | 79 | Blazers | 90 |
| February | 2, 2021 | Blazers | 106 | Kings | 103 |
| February | 5, 2021 | Blazers | 90 | Knicks | 103 |
| February | 7, 2021 | Nuggets | 95 | Blazers | 92 |
| February | 11, 2021 | Blazers | 94 | 76ers | 82 |
| February | 13, 2021 | Blazers | 82 | Rockets | 95 |
| February | 14, 2021 | Knicks | 106 | Blazers | 94 |
| February | 17, 2021 | Suns | 65 | Blazers | 95 |
| February | 19, 2021 | Blazers | 76 | Grizzlies | 80 |
| February | 21, 2021 | Bobcats | 79 | Blazers | 77 |
| February | 23, 2021 | Blazers | 80 | Pistons | 83 |
| February | 24, 2021 | Hawks | 74 | Blazers | 87 |
| March | 1, 2021 | Blazers | 84 | Pelicans | 112 |
| March | 2, 2021 | Clippers | 99 | Blazers | 78 |
| March | 3, 2021 | Grizzlies | 67 | Blazers | 91 |
| March | 9, 2021 | Blazers | 90 | Clippers | 101 |
| March | 10, 2021 | Jazz | 76 | Blazers | 86 |
| March | 13, 2021 | Celtics | 70 | Blazers | 83 |
| March | 14, 2021 | Blazers | 106 | Raptors | 95 |
| March | 16, 2021 | Blazers | 101 | Sonics | 90 |
| March | 20, 2021 | Blazers | 75 | Wolves | 91 |
| March | 24, 2021 | Blazers | 85 | Wizards | 69 |
| March | 25, 2021 | Pacers | 59 | Blazers | 88 |
| March | 26, 2021 | Blazers | 78 | Mavericks | 70 |
| March | 29, 2021 | Blazers | 80 | Warriors | 69 |
| April | 1, 2021 | Blazers | 89 | Pelicans | 102 |
| April | 4, 2021 | Blazers | 95 | Bulls | 97 |
| April | 7, 2021 | Blazers | 91 | Kings | 92 |
| April | 9, 2021 | Blazers | 106 | Magic | 104 |
| April | 10, 2021 | Wizards | 91 | Blazers | 88 |
| April | 11, 2021 | Cavaliers | 66 | Blazers | 97 |
| April | 12, 2021 | Blazers | 69 | Nets | 90 |
| April | 13, 2021 | Lakers | 72 | Blazers | 81 |
| April | 14, 2021 | Nuggets | 79 | Blazers | 104 |
| April | 15, 2021 | Warriors | 68 | Blazers | 74 |
| April | 17, 2021 | Bucks | 79 | Blazers | 82 |
| April | 18, 2021 | Blazers | 82 | Bobcats | 81 |
| April | 19, 2021 | Pistons | 73 | Blazers | 83 |
| April | 27, 2021 | Blazers | 94 | Pacers | 81 |
| April | 28, 2021 | Blazers | 79 | Celtics | 76 |
| April | 30, 2021 | Blazers | 82 | Suns | 83 |
| Post | 1, 2021 | Blazers | 85 | Pelicans | 103 |
| Post | 2, 2021 | Blazers | 92 | Pelicans | 101 |
| Post | 3, 2021 | Pelicans | 81 | Blazers | 86 |
| Post | 4, 2021 | Pelicans | 106 | Blazers | 82 |
| Post | 5, 2021 | Blazers | 63 | Pelicans | 106 |
| Post | 6, 2021 | Pelicans | | Blazers | |
| Post | 7, 2021 | Blazers | | Pelicans | |