| month | day | visitor | score | home | score |
|---|
| November | 4, 2017 | Bulls | 97 | Spurs | 100 |
| November | 6, 2017 | Lakers | 75 | Spurs | 111 |
| November | 8, 2017 | Wolves | 78 | Spurs | 80 |
| November | 9, 2017 | Grizzlies | 92 | Spurs | 103 |
| November | 12, 2017 | Raptors | 93 | Spurs | 108 |
| November | 15, 2017 | Clippers | 93 | Spurs | 83 |
| November | 17, 2017 | Spurs | 100 | Jazz | 95 |
| November | 20, 2017 | Spurs | 88 | Pacers | 89 |
| November | 23, 2017 | Spurs | 89 | Bobcats | 63 |
| November | 25, 2017 | Heat | 57 | Spurs | 91 |
| November | 30, 2017 | Spurs | 92 | Grizzlies | 87 |
| December | 1, 2017 | Suns | 89 | Spurs | 96 |
| December | 4, 2017 | Spurs | 91 | Clippers | 95 |
| December | 7, 2017 | Spurs | 71 | Celtics | 74 |
| December | 10, 2017 | Spurs | 117 | Magic | 93 |
| December | 13, 2017 | Wizards | 84 | Spurs | 90 |
| December | 15, 2017 | Suns | 84 | Spurs | 88 |
| December | 16, 2017 | Bobcats | 90 | Spurs | 101 |
| December | 17, 2017 | Knicks | 84 | Spurs | 102 |
| December | 24, 2017 | Celtics | 76 | Spurs | 82 |
| December | 25, 2017 | Jazz | 70 | Spurs | 88 |
| December | 26, 2017 | Pistons | 95 | Spurs | 106 |
| December | 27, 2017 | Spurs | 87 | Suns | 93 |
| December | 29, 2017 | Spurs | 71 | Wolves | 94 |
| December | 30, 2017 | Spurs | 74 | Lakers | 75 |
| December | 31, 2017 | Hawks | 92 | Spurs | 96 |
| January | 2, 2018 | Clippers | 80 | Spurs | 84 |
| January | 3, 2018 | Sonics | 104 | Spurs | 97 |
| January | 4, 2018 | Rockets | 86 | Spurs | 74 |
| January | 5, 2018 | Spurs | 100 | Heat | 92 |
| January | 6, 2018 | Spurs | 78 | Hawks | 99 |
| January | 7, 2018 | Spurs | 95 | Mavericks | 75 |
| January | 10, 2018 | Mavericks | 71 | Spurs | 91 |
| January | 12, 2018 | Spurs | 112 | Nets | 110 |
| January | 14, 2018 | Warriors | 97 | Spurs | 104 |
| January | 15, 2018 | Spurs | 106 | 76ers | 93 |
| January | 16, 2018 | Blazers | 102 | Spurs | 94 |
| January | 21, 2018 | Hornets | 79 | Spurs | 103 |
| January | 23, 2018 | Spurs | 105 | Hornets | 119 |
| January | 24, 2018 | Spurs | 75 | Mavericks | 82 |
| January | 26, 2018 | Spurs | 84 | Jazz | 74 |
| January | 28, 2018 | Magic | 82 | Spurs | 104 |
| February | 7, 2018 | Spurs | 84 | Sonics | 90 |
| February | 12, 2018 | Spurs | 107 | Wolves | 94 |
| February | 15, 2018 | Spurs | 101 | Warriors | 91 |
| February | 16, 2018 | Pacers | 98 | Spurs | 100 |
| February | 20, 2018 | Rockets | 101 | Spurs | 95 |
| February | 21, 2018 | Lakers | 82 | Spurs | 97 |
| February | 25, 2018 | Spurs | 97 | Rockets | 91 |
| February | 26, 2018 | Nuggets | 70 | Spurs | 81 |
| February | 27, 2018 | Spurs | 95 | Knicks | 105 |
| March | 2, 2018 | Spurs | 100 | Wizards | 102 |
| March | 4, 2018 | Spurs | 94 | Suns | 77 |
| March | 6, 2018 | Bucks | 90 | Spurs | 75 |
| March | 7, 2018 | Spurs | 93 | Bucks | 73 |
| March | 10, 2018 | Spurs | 90 | Blazers | 96 |
| March | 11, 2018 | Spurs | 85 | Kings | 77 |
| March | 12, 2018 | Nets | 73 | Spurs | 102 |
| March | 15, 2018 | Spurs | 109 | Sonics | 111 |
| March | 17, 2018 | Spurs | 94 | Hornets | 102 |
| March | 18, 2018 | Hornets | 68 | Spurs | 96 |
| March | 23, 2018 | Spurs | 75 | Kings | 78 |
| March | 25, 2018 | Jazz | 79 | Spurs | 105 |
| March | 27, 2018 | Grizzlies | 82 | Spurs | 102 |
| March | 30, 2018 | Sonics | 94 | Spurs | 95 |
| March | 31, 2018 | 76ers | 73 | Spurs | 109 |
| April | 1, 2018 | Kings | 74 | Spurs | 96 |
| April | 5, 2018 | Cavaliers | 80 | Spurs | 78 |
| April | 8, 2018 | Nuggets | 85 | Spurs | 114 |
| April | 9, 2018 | Spurs | 97 | Nuggets | 113 |
| April | 12, 2018 | Spurs | 82 | Cavaliers | 83 |
| April | 13, 2018 | Kings | 74 | Spurs | 96 |
| April | 16, 2018 | Spurs | 93 | Lakers | 74 |
| April | 17, 2018 | Spurs | 109 | Grizzlies | 84 |
| April | 20, 2018 | Spurs | 72 | Clippers | 78 |
| April | 21, 2018 | Spurs | 82 | Bulls | 87 |
| April | 22, 2018 | Spurs | 93 | Pistons | 106 |
| April | 23, 2018 | Spurs | 92 | Warriors | 80 |
| April | 25, 2018 | Mavericks | 81 | Spurs | 83 |
| April | 26, 2018 | Spurs | 105 | Raptors | 88 |
| April | 27, 2018 | Spurs | 85 | Blazers | 78 |
| April | 28, 2018 | Warriors | 78 | Spurs | 96 |
| Post | 1, 2018 | Nuggets | 95 | Spurs | 90 |
| Post | 2, 2018 | Nuggets | 95 | Spurs | 93 |
| Post | 3, 2018 | Spurs | 68 | Nuggets | 87 |
| Post | 4, 2018 | Spurs | 78 | Nuggets | 92 |
| Post | 5, 2018 | Nuggets | | Spurs | |
| Post | 6, 2018 | Spurs | | Nuggets | |
| Post | 7, 2018 | Nuggets | | Spurs | |