| month | day | visitor | score | home | score |
|---|
| November | 5, 2017 | Pistons | 71 | Celtics | 85 |
| November | 7, 2017 | Pistons | 71 | Pacers | 96 |
| November | 9, 2017 | Pistons | 90 | Celtics | 87 |
| November | 13, 2017 | Pistons | 94 | Hornets | 103 |
| November | 17, 2017 | Pistons | 91 | Rockets | 106 |
| November | 18, 2017 | 76ers | 81 | Pistons | 92 |
| November | 20, 2017 | Hornets | 100 | Pistons | 120 |
| November | 22, 2017 | Pistons | 119 | Magic | 91 |
| November | 27, 2017 | Pistons | 99 | Kings | 68 |
| November | 28, 2017 | Pistons | 87 | Hawks | 94 |
| November | 29, 2017 | Hawks | 97 | Pistons | 78 |
| November | 30, 2017 | Bucks | 79 | Pistons | 95 |
| December | 1, 2017 | Heat | 90 | Pistons | 89 |
| December | 2, 2017 | Wizards | 92 | Pistons | 94 |
| December | 4, 2017 | Grizzlies | 73 | Pistons | 99 |
| December | 5, 2017 | Celtics | 75 | Pistons | 84 |
| December | 6, 2017 | Blazers | 96 | Pistons | 78 |
| December | 7, 2017 | Mavericks | 82 | Pistons | 104 |
| December | 8, 2017 | Clippers | 95 | Pistons | 98 |
| December | 9, 2017 | Kings | 78 | Pistons | 94 |
| December | 11, 2017 | Magic | 92 | Pistons | 90 |
| December | 17, 2017 | Pistons | 90 | 76ers | 108 |
| December | 19, 2017 | Pistons | 83 | Wizards | 108 |
| December | 22, 2017 | Hawks | 78 | Pistons | 100 |
| December | 23, 2017 | Pistons | 75 | Jazz | 71 |
| December | 25, 2017 | Pistons | 111 | Knicks | 112 |
| December | 26, 2017 | Pistons | 95 | Spurs | 106 |
| December | 30, 2017 | Pistons | 110 | Wizards | 109 |
| December | 31, 2017 | Pistons | 80 | Clippers | 85 |
| January | 1, 2018 | Raptors | 103 | Pistons | 109 |
| January | 8, 2018 | Pistons | 82 | Bulls | 99 |
| January | 10, 2018 | Cavaliers | 89 | Pistons | 71 |
| January | 13, 2018 | Pistons | 106 | Nets | 122 |
| January | 14, 2018 | Celtics | 88 | Pistons | 84 |
| January | 16, 2018 | Jazz | 51 | Pistons | 106 |
| January | 17, 2018 | Pistons | 76 | Lakers | 79 |
| January | 19, 2018 | Heat | 84 | Pistons | 85 |
| January | 20, 2018 | Pacers | 121 | Pistons | 99 |
| January | 22, 2018 | Rockets | 98 | Pistons | 100 |
| January | 23, 2018 | Pistons | 101 | Nets | 75 |
| January | 24, 2018 | 76ers | 74 | Pistons | 84 |
| January | 26, 2018 | Bobcats | 103 | Pistons | 102 |
| February | 1, 2018 | Pistons | 88 | Grizzlies | 91 |
| February | 2, 2018 | Sonics | 102 | Pistons | 89 |
| February | 6, 2018 | Pistons | 82 | Heat | 83 |
| February | 11, 2018 | Lakers | 81 | Pistons | 83 |
| February | 12, 2018 | Pistons | 107 | Knicks | 106 |
| February | 13, 2018 | Pistons | 92 | Raptors | 105 |
| February | 14, 2018 | Pistons | 110 | Bobcats | 101 |
| February | 17, 2018 | Nuggets | 98 | Pistons | 117 |
| February | 18, 2018 | Pistons | 82 | Bucks | 98 |
| February | 19, 2018 | Pistons | 81 | Bobcats | 108 |
| February | 23, 2018 | Pistons | 86 | Wolves | 113 |
| February | 24, 2018 | Pacers | 96 | Pistons | 119 |
| February | 26, 2018 | Suns | 85 | Pistons | 96 |
| February | 27, 2018 | Pistons | 79 | Warriors | 83 |
| February | 28, 2018 | Magic | 92 | Pistons | 91 |
| March | 2, 2018 | Bulls | 105 | Pistons | 79 |
| March | 4, 2018 | Pistons | 109 | Magic | 93 |
| March | 5, 2018 | Pistons | 76 | Heat | 91 |
| March | 8, 2018 | Pistons | 82 | Bulls | 88 |
| March | 11, 2018 | Pistons | 68 | Cavaliers | 75 |
| March | 12, 2018 | Pistons | 75 | Mavericks | 84 |
| March | 16, 2018 | Wolves | 91 | Pistons | 105 |
| March | 19, 2018 | Nets | 92 | Pistons | 100 |
| March | 22, 2018 | Knicks | 84 | Pistons | 114 |
| March | 25, 2018 | Pistons | 112 | 76ers | 103 |
| March | 26, 2018 | Bucks | 90 | Pistons | 92 |
| March | 27, 2018 | Bulls | 86 | Pistons | 75 |
| March | 30, 2018 | Warriors | 99 | Pistons | 100 |
| March | 31, 2018 | Wizards | 93 | Pistons | 86 |
| April | 4, 2018 | Knicks | 94 | Pistons | 76 |
| April | 7, 2018 | Cavaliers | 68 | Pistons | 79 |
| April | 8, 2018 | Pistons | 104 | Raptors | 115 |
| April | 11, 2018 | Nets | 89 | Pistons | 101 |
| April | 12, 2018 | Pistons | 101 | Bucks | 104 |
| April | 15, 2018 | Pistons | 120 | Blazers | 103 |
| April | 17, 2018 | Pistons | 90 | Nuggets | 102 |
| April | 18, 2018 | Pistons | 70 | Cavaliers | 87 |
| April | 22, 2018 | Spurs | 93 | Pistons | 106 |
| April | 29, 2018 | Pistons | 90 | Sonics | 122 |
| May | 1, 2018 | Pistons | 62 | Suns | 85 |