| month | day | visitor | score | home | score |
|---|
| November | 2, 2005 | 76ers | 92 | Rockets | 83 |
| November | 3, 2005 | Bucks | 85 | Rockets | 87 |
| November | 4, 2005 | Bullets | 81 | Rockets | 87 |
| November | 5, 2005 | Spurs | 79 | Rockets | 91 |
| November | 7, 2005 | Rockets | 84 | Jazz | 80 |
| November | 10, 2005 | Rockets | 76 | 76ers | 82 |
| November | 11, 2005 | Rockets | 83 | Bucks | 90 |
| November | 12, 2005 | Rockets | 85 | Bullets | 91 |
| November | 13, 2005 | Spurs | 62 | Rockets | 85 |
| November | 15, 2005 | Rockets | 78 | Jazz | 75 |
| November | 20, 2005 | 76ers | 80 | Rockets | 92 |
| November | 21, 2005 | Bucks | 107 | Rockets | 75 |
| November | 22, 2005 | Bullets | 78 | Rockets | 76 |
| November | 23, 2005 | Spurs | 68 | Rockets | 92 |
| November | 25, 2005 | Rockets | 82 | Jazz | 73 |
| December | 1, 2005 | Rockets | 96 | Spurs | 82 |
| December | 3, 2005 | Bucks | 78 | Rockets | 88 |
| December | 4, 2005 | Bullets | 62 | Rockets | 85 |
| December | 5, 2005 | Jazz | 68 | Rockets | 96 |
| December | 7, 2005 | 76ers | 89 | Rockets | 85 |
| December | 9, 2005 | Spurs | 76 | Rockets | 85 |
| December | 10, 2005 | 76ers | 86 | Rockets | 79 |
| December | 11, 2005 | Rockets | | Nets | |
| December | 12, 2005 | Rockets | | Raptors | |
| December | 17, 2005 | Jazz | | Rockets | |
| December | 19, 2005 | Rockets | | 76ers | |
| December | 21, 2005 | Jazz | | Rockets | |
| December | 23, 2005 | Rockets | | Spurs | |
| December | 24, 2005 | Bulls | | Rockets | |
| December | 29, 2005 | Pacers | | Rockets | |
| December | 31, 2005 | Raptors | | Rockets | |
| January | 1, 2006 | Cavaliers | | Rockets | |
| January | 9, 2006 | Mavericks | | Rockets | |
| January | 11, 2006 | Rockets | | Hawks | |
| January | 15, 2006 | Grizzlies | | Rockets | |
| January | 16, 2006 | Jazz | | Rockets | |
| January | 18, 2006 | Hawks | | Rockets | |
| January | 24, 2006 | Rockets | | Mavericks | |
| January | 26, 2006 | Rockets | | Nuggets | |
| January | 27, 2006 | Blazers | | Rockets | |
| January | 28, 2006 | Rockets | | Bucks | |
| January | 29, 2006 | Pistons | | Rockets | |
| January | 30, 2006 | Rockets | | Blazers | |
| January | 31, 2006 | Hornets | | Rockets | |
| February | 4, 2006 | Rockets | | Cavaliers | |
| February | 10, 2006 | Rockets | | Heat | |
| February | 12, 2006 | Rockets | | Spurs | |
| February | 13, 2006 | Lakers | | Rockets | |
| February | 15, 2006 | Rockets | | Wolves | |
| February | 17, 2006 | Rockets | | Jazz | |
| February | 21, 2006 | Rockets | | Blazers | |
| February | 22, 2006 | Rockets | | Knicks | |
| February | 23, 2006 | Rockets | | Suns | |
| March | 1, 2006 | Spurs | | Rockets | |
| March | 2, 2006 | Rockets | | Lakers | |
| March | 5, 2006 | Lakers | | Rockets | |
| March | 6, 2006 | Nuggets | | Rockets | |
| March | 7, 2006 | Kings | | Rockets | |
| March | 9, 2006 | Rockets | | Pacers | |
| March | 10, 2006 | Nuggets | | Rockets | |
| March | 13, 2006 | Magic | | Rockets | |
| March | 14, 2006 | Rockets | | Clippers | |
| March | 17, 2006 | Rockets | | Mavericks | |
| March | 18, 2006 | Nuggets | | Rockets | |
| March | 21, 2006 | Bucks | | Rockets | |
| March | 22, 2006 | Rockets | | Wolves | |
| March | 23, 2006 | Rockets | | Jazz | |
| March | 24, 2006 | Spurs | | Rockets | |
| March | 25, 2006 | Mavericks | | Rockets | |
| March | 29, 2006 | Celtics | | Rockets | |
| March | 31, 2006 | Rockets | | Magic | |
| April | 4, 2006 | 76ers | | Rockets | |
| April | 6, 2006 | Wolves | | Rockets | |
| April | 9, 2006 | Warriors | | Rockets | |
| April | 12, 2006 | Mavericks | | Rockets | |
| April | 14, 2006 | Rockets | | Nuggets | |
| April | 19, 2006 | Rockets | | Warriors | |
| April | 20, 2006 | Clippers | | Rockets | |
| April | 21, 2006 | Rockets | | Bullets | |
| April | 22, 2006 | Rockets | | Bulls | |
| April | 23, 2006 | Rockets | | Spurs | |
| April | 24, 2006 | Rockets | | Lakers | |
| April | 25, 2006 | Rockets | | Clippers | |