| month | day | visitor | score | home | score |
|---|
| November | 3, 2005 | Blazers | 88 | Jazz | 100 |
| November | 7, 2005 | Nets | 71 | Blazers | 78 |
| November | 9, 2005 | Blazers | 78 | Warriors | 81 |
| November | 10, 2005 | Blazers | 78 | Heat | 74 |
| November | 11, 2005 | Suns | 96 | Blazers | 98 |
| November | 12, 2005 | Clippers | 89 | Blazers | 100 |
| November | 15, 2005 | Blazers | 94 | Clippers | 88 |
| November | 17, 2005 | Spurs | 72 | Blazers | 96 |
| November | 18, 2005 | Blazers | 99 | Clippers | 101 |
| November | 19, 2005 | Magic | 116 | Blazers | 95 |
| November | 20, 2005 | Blazers | 87 | Nets | 75 |
| November | 22, 2005 | 76ers | 102 | Blazers | 86 |
| November | 27, 2005 | Blazers | 97 | Warriors | 93 |
| November | 30, 2005 | Blazers | 98 | Nuggets | 122 |
| December | 1, 2005 | Blazers | 102 | Lakers | 107 |
| December | 4, 2005 | Cavaliers | 102 | Blazers | 90 |
| December | 7, 2005 | Blazers | 95 | Celtics | 102 |
| December | 10, 2005 | Hawks | 120 | Blazers | 105 |
| December | 11, 2005 | Blazers | 92 | Pacers | 102 |
| December | 13, 2005 | Nuggets | 105 | Blazers | 121 |
| December | 14, 2005 | Blazers | 84 | Suns | 82 |
| December | 15, 2005 | Wolves | 107 | Blazers | 108 |
| December | 16, 2005 | Blazers | 88 | Grizzlies | 80 |
| December | 21, 2005 | Blazers | 93 | Sonics | 79 |
| December | 22, 2005 | Lakers | 92 | Blazers | 89 |
| December | 23, 2005 | Blazers | 83 | Pistons | 97 |
| December | 24, 2005 | Blazers | 79 | Raptors | 106 |
| December | 26, 2005 | Heat | 71 | Blazers | 83 |
| December | 27, 2005 | Spurs | 84 | Blazers | 106 |
| December | 29, 2005 | Blazers | | Spurs | |
| December | 30, 2005 | Blazers | | Mavericks | |
| December | 31, 2005 | Pistons | | Blazers | |
| January | 2, 2006 | Bullets | | Blazers | |
| January | 3, 2006 | Blazers | | Cavaliers | |
| January | 5, 2006 | Warriors | | Blazers | |
| January | 6, 2006 | Blazers | | Hawks | |
| January | 7, 2006 | Blazers | | Warriors | |
| January | 8, 2006 | Raptors | | Blazers | |
| January | 9, 2006 | Kings | | Blazers | |
| January | 11, 2006 | Grizzlies | | Blazers | |
| January | 13, 2006 | Blazers | | Lakers | |
| January | 14, 2006 | Blazers | | Bulls | |
| January | 22, 2006 | Blazers | | Sonics | |
| January | 27, 2006 | Blazers | | Rockets | |
| January | 29, 2006 | Blazers | | Sonics | |
| January | 30, 2006 | Rockets | | Blazers | |
| February | 2, 2006 | Lakers | | Blazers | |
| February | 10, 2006 | Sonics | | Blazers | |
| February | 11, 2006 | Blazers | | Lakers | |
| February | 16, 2006 | Blazers | | Knicks | |
| February | 17, 2006 | Knicks | | Blazers | |
| February | 18, 2006 | Grizzlies | | Blazers | |
| February | 19, 2006 | Wolves | | Blazers | |
| February | 20, 2006 | Nuggets | | Blazers | |
| February | 21, 2006 | Rockets | | Blazers | |
| February | 24, 2006 | Blazers | | 76ers | |
| February | 25, 2006 | Hornets | | Blazers | |
| February | 27, 2006 | Bucks | | Blazers | |
| February | 28, 2006 | Blazers | | Kings | |
| March | 4, 2006 | Blazers | | Kings | |
| March | 7, 2006 | Jazz | | Blazers | |
| March | 8, 2006 | Kings | | Blazers | |
| March | 9, 2006 | Blazers | | Suns | |
| March | 10, 2006 | Blazers | | Bullets | |
| March | 11, 2006 | Blazers | | Hornets | |
| March | 14, 2006 | Celtics | | Blazers | |
| March | 18, 2006 | Blazers | | Jazz | |
| March | 19, 2006 | Pacers | | Blazers | |
| March | 20, 2006 | Blazers | | Suns | |
| March | 26, 2006 | Blazers | | Clippers | |
| March | 28, 2006 | Suns | | Blazers | |
| March | 31, 2006 | Bulls | | Blazers | |
| April | 1, 2006 | Clippers | | Blazers | |
| April | 4, 2006 | Blazers | | Bucks | |
| April | 5, 2006 | Warriors | | Blazers | |
| April | 9, 2006 | Mavericks | | Blazers | |
| April | 11, 2006 | Blazers | | Kings | |
| April | 12, 2006 | Sonics | | Blazers | |
| April | 13, 2006 | Mavericks | | Blazers | |
| April | 15, 2006 | Blazers | | Magic | |
| April | 19, 2006 | Jazz | | Blazers | |
| April | 24, 2006 | Blazers | | Wolves | |