| month | day | visitor | score | home | score |
|---|
| November | 3, 2005 | Mavericks | 94 | 76ers | 120 |
| November | 5, 2005 | Celtics | 119 | 76ers | 116 |
| November | 8, 2005 | 76ers | 119 | Cavaliers | 96 |
| November | 9, 2005 | 76ers | 110 | Wolves | 106 |
| November | 10, 2005 | 76ers | 126 | Bullets | 101 |
| November | 11, 2005 | Warriors | 97 | 76ers | 130 |
| November | 12, 2005 | Suns | 92 | 76ers | 108 |
| November | 13, 2005 | Cavaliers | 94 | 76ers | 118 |
| November | 15, 2005 | 76ers | 117 | Celtics | 106 |
| November | 21, 2005 | Bucks | 78 | 76ers | 113 |
| November | 22, 2005 | 76ers | 102 | Blazers | 86 |
| November | 24, 2005 | 76ers | 105 | Knicks | 114 |
| November | 28, 2005 | 76ers | 125 | Hornets | 132 |
| November | 29, 2005 | 76ers | 118 | Nets | 75 |
| November | 30, 2005 | Pistons | 102 | 76ers | 114 |
| December | 1, 2005 | Magic | 88 | 76ers | 102 |
| December | 6, 2005 | Bulls | 101 | 76ers | 104 |
| December | 9, 2005 | 76ers | 137 | Knicks | 117 |
| December | 10, 2005 | Bulls | 74 | 76ers | 103 |
| December | 12, 2005 | 76ers | 114 | Sonics | 87 |
| December | 13, 2005 | 76ers | 134 | Knicks | 111 |
| December | 16, 2005 | Hawks | 124 | 76ers | 118 |
| December | 19, 2005 | Rockets | 88 | 76ers | 120 |
| December | 20, 2005 | Pacers | 99 | 76ers | 123 |
| December | 22, 2005 | 76ers | 114 | Warriors | 94 |
| December | 25, 2005 | 76ers | 115 | Jazz | 123 |
| December | 26, 2005 | Knicks | 95 | 76ers | 128 |
| December | 27, 2005 | Pistons | 103 | 76ers | 98 |
| December | 28, 2005 | 76ers | 100 | Nets | 82 |
| December | 29, 2005 | 76ers | | Bulls | |
| January | 3, 2006 | Heat | | 76ers | |
| January | 4, 2006 | 76ers | | Celtics | |
| January | 6, 2006 | Knicks | | 76ers | |
| January | 7, 2006 | Clippers | | 76ers | |
| January | 12, 2006 | 76ers | | Raptors | |
| January | 14, 2006 | 76ers | | Mavericks | |
| January | 15, 2006 | 76ers | | Heat | |
| January | 18, 2006 | Celtics | | 76ers | |
| January | 21, 2006 | Hornets | | 76ers | |
| January | 22, 2006 | 76ers | | Magic | |
| January | 23, 2006 | 76ers | | Suns | |
| January | 24, 2006 | 76ers | | Bullets | |
| January | 25, 2006 | Sonics | | 76ers | |
| January | 30, 2006 | Bullets | | 76ers | |
| February | 8, 2006 | 76ers | | Bullets | |
| February | 11, 2006 | 76ers | | Nuggets | |
| February | 14, 2006 | Jazz | | 76ers | |
| February | 17, 2006 | Raptors | | 76ers | |
| February | 22, 2006 | Nets | | 76ers | |
| February | 23, 2006 | Grizzlies | | 76ers | |
| February | 24, 2006 | Blazers | | 76ers | |
| February | 26, 2006 | Hornets | | 76ers | |
| February | 28, 2006 | 76ers | | Bucks | |
| March | 1, 2006 | Lakers | | 76ers | |
| March | 2, 2006 | 76ers | | Celtics | |
| March | 3, 2006 | Hawks | | 76ers | |
| March | 7, 2006 | Raptors | | 76ers | |
| March | 10, 2006 | 76ers | | Kings | |
| March | 11, 2006 | Nuggets | | 76ers | |
| March | 12, 2006 | 76ers | | Magic | |
| March | 13, 2006 | Pacers | | 76ers | |
| March | 15, 2006 | Spurs | | 76ers | |
| March | 18, 2006 | Cavaliers | | 76ers | |
| March | 22, 2006 | 76ers | | Nets | |
| March | 25, 2006 | 76ers | | Hawks | |
| March | 27, 2006 | Kings | | 76ers | |
| March | 28, 2006 | 76ers | | Pacers | |
| April | 1, 2006 | 76ers | | Spurs | |
| April | 3, 2006 | 76ers | | Pistons | |
| April | 4, 2006 | 76ers | | Rockets | |
| April | 6, 2006 | Heat | | 76ers | |
| April | 7, 2006 | Wolves | | 76ers | |
| April | 8, 2006 | 76ers | | Heat | |
| April | 10, 2006 | Nets | | 76ers | |
| April | 12, 2006 | Magic | | 76ers | |
| April | 15, 2006 | 76ers | | Bucks | |
| April | 16, 2006 | 76ers | | Heat | |
| April | 17, 2006 | 76ers | | Clippers | |
| April | 19, 2006 | Bullets | | 76ers | |
| April | 20, 2006 | 76ers | | Grizzlies | |
| April | 22, 2006 | 76ers | | Magic | |
| April | 23, 2006 | 76ers | | Lakers | |