| month | day | visitor | score | home | score |
|---|
| November | 10, 1999 | Wolves | 100 | Spurs | 99 |
| November | 12, 1999 | Spurs | 111 | Blazers | 116 |
| November | 15, 1999 | Warriors | 104 | Spurs | 114 |
| November | 16, 1999 | Lakers | 107 | Spurs | 122 |
| November | 17, 1999 | Spurs | 80 | Celtics | 101 |
| November | 18, 1999 | Spurs | 84 | Kings | 105 |
| November | 19, 1999 | Pistons | 87 | Spurs | 83 |
| November | 21, 1999 | Sonics | 112 | Spurs | 99 |
| November | 22, 1999 | Spurs | 92 | Mavericks | 107 |
| November | 23, 1999 | Cavaliers | 82 | Spurs | 98 |
| November | 26, 1999 | Suns | 124 | Spurs | 103 |
| November | 28, 1999 | Spurs | 106 | Magic | 110 |
| November | 30, 1999 | Spurs | 100 | Jazz | 105 |
| December | 1, 1999 | Bulls | 102 | Spurs | 119 |
| December | 6, 1999 | Spurs | 103 | Warriors | 97 |
| December | 7, 1999 | Nuggets | 99 | Spurs | 96 |
| December | 8, 1999 | Spurs | 98 | 76ers | 113 |
| December | 9, 1999 | Spurs | 86 | Suns | 101 |
| December | 10, 1999 | Rockets | 94 | Spurs | 104 |
| December | 13, 1999 | Spurs | 89 | Lakers | 113 |
| December | 14, 1999 | 76ers | 97 | Spurs | 88 |
| December | 18, 1999 | Wolves | 111 | Spurs | 114 |
| December | 19, 1999 | Spurs | 95 | Blazers | 115 |
| December | 22, 1999 | Spurs | 103 | Rockets | 108 |
| December | 26, 1999 | Magic | 101 | Spurs | 97 |
| December | 28, 1999 | Spurs | 93 | Knicks | 114 |
| December | 29, 1999 | Knicks | 113 | Spurs | 93 |
| January | 7, 2000 | Mavericks | 116 | Spurs | 84 |
| January | 9, 2000 | Spurs | 76 | Mavericks | 103 |
| January | 10, 2000 | Spurs | 106 | Raptors | 111 |
| January | 11, 2000 | Spurs | 60 | Kings | 106 |
| January | 12, 2000 | Spurs | 90 | Pistons | 88 |
| January | 14, 2000 | Spurs | 86 | Grizzlies | 98 |
| January | 15, 2000 | Mavericks | 74 | Spurs | 86 |
| January | 17, 2000 | Spurs | 107 | Wolves | 102 |
| January | 18, 2000 | Spurs | 62 | Bullets | 68 |
| January | 19, 2000 | Jazz | 91 | Spurs | 103 |
| January | 24, 2000 | Grizzlies | 95 | Spurs | 94 |
| January | 27, 2000 | Spurs | 97 | Lakers | 90 |
| January | 30, 2000 | Heat | 75 | Spurs | 90 |
| February | 2, 2000 | Spurs | 94 | Jazz | 98 |
| February | 4, 2000 | Sonics | 94 | Spurs | 111 |
| February | 8, 2000 | Spurs | 85 | Bucks | 100 |
| February | 9, 2000 | Spurs | 72 | Rockets | 97 |
| February | 11, 2000 | Spurs | 96 | Hawks | 137 |
| February | 14, 2000 | Spurs | 107 | Wolves | 116 |
| February | 15, 2000 | Spurs | 95 | Clippers | 119 |
| February | 18, 2000 | Warriors | 84 | Spurs | 95 |
| February | 19, 2000 | Mavericks | 91 | Spurs | 103 |
| February | 20, 2000 | Suns | 97 | Spurs | 68 |
| February | 26, 2000 | Spurs | 94 | Nets | 93 |
| February | 27, 2000 | Spurs | 85 | Heat | 94 |
| March | 1, 2000 | Blazers | 95 | Spurs | 107 |
| March | 2, 2000 | Celtics | 101 | Spurs | 95 |
| March | 4, 2000 | Nuggets | 81 | Spurs | 64 |
| March | 6, 2000 | Pacers | 89 | Spurs | 94 |
| March | 8, 2000 | Grizzlies | 86 | Spurs | 87 |
| March | 11, 2000 | Hornets | 81 | Spurs | 96 |
| March | 12, 2000 | Spurs | 78 | Nuggets | 99 |
| March | 14, 2000 | Spurs | 90 | Sonics | 112 |
| March | 19, 2000 | Spurs | 94 | Pacers | 81 |
| March | 24, 2000 | Nuggets | 93 | Spurs | 84 |
| March | 25, 2000 | Spurs | 92 | Clippers | 112 |
| March | 26, 2000 | Bullets | 86 | Spurs | 103 |
| March | 29, 2000 | Spurs | 101 | Grizzlies | 99 |
| March | 31, 2000 | Jazz | 88 | Spurs | 94 |
| April | 1, 2000 | Spurs | 98 | Hornets | 100 |
| April | 2, 2000 | Spurs | 98 | Grizzlies | 110 |
| April | 6, 2000 | Rockets | 74 | Spurs | 93 |
| April | 7, 2000 | Kings | 112 | Spurs | 94 |
| April | 11, 2000 | Spurs | 92 | Nuggets | 95 |
| April | 12, 2000 | Jazz | 78 | Spurs | 91 |
| April | 13, 2000 | Bucks | 105 | Spurs | 79 |
| April | 14, 2000 | Nets | 85 | Spurs | 80 |
| April | 15, 2000 | Spurs | 103 | Wolves | 97 |
| April | 16, 2000 | Rockets | 81 | Spurs | 95 |
| April | 17, 2000 | Clippers | 113 | Spurs | 98 |
| April | 19, 2000 | Spurs | 87 | Sonics | 90 |
| April | 20, 2000 | Spurs | 94 | Cavaliers | 100 |
| April | 21, 2000 | Spurs | 99 | Bulls | 118 |
| April | 24, 2000 | Raptors | 112 | Spurs | 122 |
| April | 25, 2000 | Hawks | 104 | Spurs | 100 |