| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Knicks | 100 | Hornets | 117 |
| November | 5, 2020 | Suns | 103 | Knicks | 118 |
| November | 8, 2020 | Knicks | 96 | Raptors | 115 |
| November | 12, 2020 | Knicks | 76 | Raptors | 111 |
| November | 13, 2020 | Cavaliers | 114 | Knicks | 117 |
| November | 16, 2020 | Celtics | 107 | Knicks | 112 |
| November | 17, 2020 | Heat | 119 | Knicks | 98 |
| November | 18, 2020 | Knicks | 100 | Timberwolves | 90 |
| November | 20, 2020 | Knicks | 111 | Pistons | 124 |
| November | 22, 2020 | Knicks | 117 | Grizzlies | 121 |
| November | 26, 2020 | Knicks | 113 | Celtics | 95 |
| November | 28, 2020 | Heat | 128 | Knicks | 106 |
| December | 2, 2020 | Knicks | 108 | Rockets | 114 |
| December | 3, 2020 | Clippers | 86 | Knicks | 115 |
| December | 4, 2020 | Hornets | 98 | Knicks | 103 |
| December | 5, 2020 | Knicks | 110 | 76ers | 104 |
| December | 7, 2020 | Knicks | 110 | Grizzlies | 106 |
| December | 8, 2020 | Knicks | 102 | Hornets | 134 |
| December | 10, 2020 | Knicks | 109 | Suns | 91 |
| December | 12, 2020 | Sonics | 102 | Knicks | 114 |
| December | 15, 2020 | Warriors | 132 | Knicks | 106 |
| December | 16, 2020 | Knicks | 102 | Spurs | 110 |
| December | 18, 2020 | Celtics | 136 | Knicks | 137 |
| December | 21, 2020 | Raptors | 119 | Knicks | 116 |
| December | 23, 2020 | Pistons | 104 | Knicks | 118 |
| December | 24, 2020 | Knicks | 112 | 76ers | 117 |
| December | 26, 2020 | Raptors | 102 | Knicks | 145 |
| December | 28, 2020 | 76ers | 94 | Knicks | 109 |
| December | 29, 2020 | Knicks | 99 | 76ers | 104 |
| January | 1, 2021 | Knicks | 109 | Hornets | 119 |
| January | 2, 2021 | Rockets | 95 | Knicks | 126 |
| January | 4, 2021 | 76ers | 113 | Knicks | 117 |
| January | 6, 2021 | Raptors | 119 | Knicks | 135 |
| January | 8, 2021 | Knicks | 112 | Nuggets | 119 |
| January | 10, 2021 | Knicks | 125 | Clippers | 105 |
| January | 12, 2021 | Pistons | 105 | Knicks | 110 |
| January | 13, 2021 | Knicks | 116 | Celtics | 108 |
| January | 15, 2021 | Celtics | 111 | Knicks | 119 |
| January | 16, 2021 | Knicks | 84 | Bulls | 97 |
| January | 17, 2021 | Jazz | 94 | Knicks | 114 |
| January | 19, 2021 | 76ers | 108 | Knicks | 126 |
| January | 23, 2021 | Nuggets | 116 | Knicks | 128 |
| January | 25, 2021 | Knicks | 125 | Lakers | 119 |
| February | 5, 2021 | Knicks | 116 | Raptors | 135 |
| February | 6, 2021 | Spurs | 73 | Knicks | 110 |
| February | 7, 2021 | Knicks | 101 | Cavaliers | 146 |
| February | 9, 2021 | Knicks | 103 | Cavaliers | 106 |
| February | 11, 2021 | Knicks | 93 | Jazz | 107 |
| February | 12, 2021 | Pistons | 87 | Knicks | 125 |
| February | 13, 2021 | Grizzlies | 109 | Knicks | 127 |
| February | 15, 2021 | Hornets | 123 | Knicks | 104 |
| February | 16, 2021 | Grizzlies | 89 | Knicks | 122 |
| February | 19, 2021 | Heat | 105 | Knicks | 113 |
| February | 22, 2021 | Cavaliers | 107 | Knicks | 99 |
| February | 25, 2021 | Knicks | 106 | Sonics | 119 |
| February | 26, 2021 | Pistons | 98 | Knicks | 103 |
| March | 1, 2021 | Grizzlies | 99 | Knicks | 116 |
| March | 2, 2021 | Heat | 114 | Knicks | 113 |
| March | 6, 2021 | Celtics | 105 | Knicks | 90 |
| March | 11, 2021 | Knicks | 110 | Grizzlies | 108 |
| March | 12, 2021 | Knicks | 112 | Cavaliers | 109 |
| March | 14, 2021 | Knicks | 109 | Warriors | 113 |
| March | 16, 2021 | Knicks | 111 | Heat | 114 |
| March | 17, 2021 | Knicks | 94 | Hornets | 129 |
| March | 18, 2021 | Bulls | 104 | Knicks | 90 |
| March | 19, 2021 | 76ers | 109 | Knicks | 103 |
| March | 20, 2021 | Knicks | 121 | Heat | 132 |
| March | 26, 2021 | Knicks | 93 | Cavaliers | 120 |
| March | 27, 2021 | Heat | 111 | Knicks | 93 |
| April | 1, 2021 | Knicks | 107 | Pistons | 119 |
| April | 2, 2021 | Knicks | 95 | Hornets | 121 |
| April | 3, 2021 | Cavaliers | 111 | Knicks | 119 |
| April | 4, 2021 | Knicks | 97 | Bulls | 121 |
| April | 5, 2021 | Knicks | 105 | Bulls | 124 |
| April | 6, 2021 | Knicks | 114 | Celtics | 116 |
| April | 10, 2021 | Bulls | 99 | Knicks | 100 |
| April | 11, 2021 | Grizzlies | 100 | Knicks | 110 |
| April | 12, 2021 | Knicks | 134 | Raptors | 96 |
| April | 13, 2021 | Knicks | 109 | Bulls | 113 |
| April | 14, 2021 | Lakers | 97 | Knicks | 129 |
| April | 15, 2021 | Knicks | 119 | Pistons | 122 |
| April | 17, 2021 | Timberwolves | 85 | Knicks | 121 |
| Post | 1, 2021 | Knicks | 90 | Bulls | 105 |
| Post | 2, 2021 | Knicks | 87 | Bulls | 113 |
| Post | 3, 2021 | Bulls | 100 | Knicks | 110 |
| Post | 4, 2021 | Bulls | 111 | Knicks | 101 |
| Post | 5, 2021 | Knicks | 76 | Bulls | 106 |
| Post | 6, 2021 | Bulls | | Knicks | |
| Post | 7, 2021 | Knicks | | Bulls | |