| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Spurs | 94 | Celtics | 105 |
| November | 3, 2020 | Cavaliers | 99 | Celtics | 112 |
| November | 4, 2020 | Heat | 120 | Celtics | 123 |
| November | 5, 2020 | Celtics | 118 | Clippers | 96 |
| November | 7, 2020 | Pistons | 100 | Celtics | 90 |
| November | 9, 2020 | Sonics | 97 | Celtics | 100 |
| November | 13, 2020 | Celtics | 105 | Suns | 103 |
| November | 14, 2020 | Celtics | 110 | Heat | 111 |
| November | 16, 2020 | Celtics | 107 | Knicks | 112 |
| November | 18, 2020 | Bulls | 99 | Celtics | 89 |
| November | 19, 2020 | Celtics | 77 | Bulls | 94 |
| November | 24, 2020 | Celtics | 94 | Hornets | 105 |
| November | 25, 2020 | Hornets | 105 | Celtics | 113 |
| November | 26, 2020 | Knicks | 113 | Celtics | 95 |
| November | 27, 2020 | Rockets | 78 | Celtics | 91 |
| November | 28, 2020 | Celtics | 134 | Cavaliers | 107 |
| November | 29, 2020 | Raptors | 79 | Celtics | 93 |
| November | 30, 2020 | 76ers | 102 | Celtics | 108 |
| December | 2, 2020 | 76ers | 99 | Celtics | 114 |
| December | 3, 2020 | Celtics | 88 | Raptors | 78 |
| December | 5, 2020 | Celtics | 95 | Grizzlies | 83 |
| December | 6, 2020 | Celtics | 102 | Rockets | 84 |
| December | 10, 2020 | Celtics | 102 | Nuggets | 93 |
| December | 16, 2020 | Celtics | 99 | Cavaliers | 113 |
| December | 18, 2020 | Celtics | 136 | Knicks | 137 |
| December | 19, 2020 | Bulls | 99 | Celtics | 101 |
| December | 22, 2020 | Heat | 109 | Celtics | 113 |
| December | 24, 2020 | Hornets | 115 | Celtics | 107 |
| December | 25, 2020 | Celtics | 101 | Heat | 98 |
| December | 30, 2020 | Suns | 95 | Celtics | 103 |
| January | 2, 2021 | Celtics | 99 | Hornets | 115 |
| January | 3, 2021 | Celtics | 94 | Raptors | 110 |
| January | 4, 2021 | Grizzlies | 82 | Celtics | 91 |
| January | 8, 2021 | Pistons | 103 | Celtics | 108 |
| January | 9, 2021 | Celtics | 98 | Hornets | 105 |
| January | 10, 2021 | Grizzlies | 72 | Celtics | 93 |
| January | 11, 2021 | Hornets | 99 | Celtics | 114 |
| January | 13, 2021 | Knicks | 116 | Celtics | 108 |
| January | 15, 2021 | Celtics | 111 | Knicks | 119 |
| January | 16, 2021 | Celtics | 103 | Grizzlies | 85 |
| January | 19, 2021 | Cavaliers | 90 | Celtics | 98 |
| January | 22, 2021 | 76ers | 108 | Celtics | 104 |
| January | 23, 2021 | Celtics | 125 | Timberwolves | 102 |
| January | 25, 2021 | Celtics | 118 | Heat | 112 |
| January | 26, 2021 | Celtics | 94 | Heat | 110 |
| January | 28, 2021 | Celtics | 92 | 76ers | 119 |
| February | 5, 2021 | Warriors | 109 | Celtics | 113 |
| February | 7, 2021 | Nuggets | 98 | Celtics | 109 |
| February | 8, 2021 | Celtics | 112 | Grizzlies | 91 |
| February | 10, 2021 | Celtics | 92 | Bulls | 91 |
| February | 11, 2021 | Celtics | 103 | 76ers | 135 |
| February | 14, 2021 | Raptors | 96 | Celtics | 103 |
| February | 15, 2021 | Pistons | 115 | Celtics | 107 |
| February | 16, 2021 | Raptors | 101 | Celtics | 105 |
| February | 18, 2021 | Celtics | 119 | Lakers | 105 |
| February | 19, 2021 | Raptors | 103 | Celtics | 104 |
| February | 21, 2021 | Celtics | 91 | Jazz | 99 |
| February | 23, 2021 | Celtics | 119 | Pistons | 129 |
| February | 25, 2021 | Bulls | 82 | Celtics | 80 |
| March | 2, 2021 | Grizzlies | 96 | Celtics | 98 |
| March | 3, 2021 | Celtics | 107 | Raptors | 104 |
| March | 6, 2021 | Celtics | 105 | Knicks | 90 |
| March | 7, 2021 | Celtics | 69 | Heat | 115 |
| March | 8, 2021 | Celtics | 121 | Warriors | 117 |
| March | 9, 2021 | Celtics | 99 | Sonics | 104 |
| March | 11, 2021 | Lakers | 117 | Celtics | 119 |
| March | 12, 2021 | Celtics | 79 | Bulls | 105 |
| March | 15, 2021 | Celtics | 98 | Hornets | 107 |
| March | 19, 2021 | Celtics | 92 | Pistons | 114 |
| March | 23, 2021 | Hornets | 122 | Celtics | 108 |
| March | 26, 2021 | Celtics | 116 | 76ers | 110 |
| March | 29, 2021 | Cavaliers | 75 | Celtics | 100 |
| April | 1, 2021 | Celtics | 119 | Spurs | 77 |
| April | 6, 2021 | Knicks | 114 | Celtics | 116 |
| April | 7, 2021 | 76ers | 93 | Celtics | 110 |
| April | 8, 2021 | Jazz | 95 | Celtics | 86 |
| April | 10, 2021 | Cavaliers | 104 | Celtics | 102 |
| April | 11, 2021 | Bulls | 70 | Celtics | 92 |
| April | 14, 2021 | Timberwolves | 87 | Celtics | 112 |
| April | 16, 2021 | Celtics | 126 | Pistons | 133 |
| April | 17, 2021 | Celtics | 98 | Cavaliers | 85 |
| April | 19, 2021 | Clippers | 85 | Celtics | 92 |
| Post | 1, 2021 | Pistons | 103 | Celtics | 111 |
| Post | 2, 2021 | Pistons | 111 | Celtics | 106 |
| Post | 3, 2021 | Celtics | 111 | Pistons | 113 |
| Post | 4, 2021 | Celtics | 132 | Pistons | 101 |
| Post | 5, 2021 | Pistons | 100 | Celtics | 116 |
| Post | 6, 2021 | Celtics | 120 | Pistons | 117 |
| Post | 7, 2021 | Pistons | | Celtics | |
| Post | 8, 2021 | Celtics | 114 | Heat | 120 |
| Post | 9, 2021 | Celtics | 113 | Heat | 121 |
| Post | 10, 2021 | Heat | 110 | Celtics | 119 |
| Post | 11, 2021 | Heat | 116 | Celtics | 113 |
| Post | 12, 2021 | Celtics | 127 | Heat | 100 |
| Post | 13, 2021 | Heat | 113 | Celtics | 101 |
| Post | 14, 2021 | Celtics | | Heat | |