| month | day | visitor | score | home | score |
|---|
| November | 4, 2020 | Bulls | 110 | Cavaliers | 104 |
| November | 5, 2020 | Bulls | 104 | 76ers | 116 |
| November | 6, 2020 | Bulls | 129 | Sonics | 99 |
| November | 7, 2020 | Heat | 121 | Bulls | 111 |
| November | 8, 2020 | Jazz | 91 | Bulls | 85 |
| November | 10, 2020 | Pistons | 99 | Bulls | 106 |
| November | 11, 2020 | Bulls | 97 | Pistons | 100 |
| November | 14, 2020 | Bulls | 110 | Lakers | 120 |
| November | 16, 2020 | Heat | 109 | Bulls | 111 |
| November | 17, 2020 | 76ers | 91 | Bulls | 111 |
| November | 18, 2020 | Bulls | 99 | Celtics | 89 |
| November | 19, 2020 | Celtics | 77 | Bulls | 94 |
| November | 21, 2020 | Hornets | 96 | Bulls | 125 |
| November | 22, 2020 | Bulls | 89 | Raptors | 78 |
| November | 23, 2020 | Hornets | 113 | Bulls | 100 |
| November | 24, 2020 | Bulls | 100 | Nuggets | 81 |
| November | 25, 2020 | Grizzlies | 101 | Bulls | 108 |
| November | 28, 2020 | Sonics | 94 | Bulls | 110 |
| December | 1, 2020 | Clippers | 80 | Bulls | 100 |
| December | 7, 2020 | Hornets | 101 | Bulls | 111 |
| December | 8, 2020 | Bulls | 117 | Cavaliers | 104 |
| December | 12, 2020 | Cavaliers | 95 | Bulls | 101 |
| December | 13, 2020 | Bulls | 101 | Raptors | 89 |
| December | 15, 2020 | 76ers | 118 | Bulls | 114 |
| December | 16, 2020 | Nuggets | 95 | Bulls | 98 |
| December | 17, 2020 | Timberwolves | 85 | Bulls | 86 |
| December | 18, 2020 | Bulls | 94 | Grizzlies | 85 |
| December | 19, 2020 | Bulls | 99 | Celtics | 101 |
| December | 20, 2020 | Bulls | 93 | Heat | 104 |
| December | 23, 2020 | Bulls | 116 | Cavaliers | 90 |
| December | 24, 2020 | Bulls | 76 | Rockets | 98 |
| December | 25, 2020 | Bulls | 110 | Pistons | 119 |
| December | 26, 2020 | Bulls | 106 | Cavaliers | 101 |
| December | 27, 2020 | Pistons | 97 | Bulls | 64 |
| December | 28, 2020 | Raptors | 109 | Bulls | 104 |
| December | 30, 2020 | Heat | 120 | Bulls | 116 |
| December | 31, 2020 | Bulls | 86 | Grizzlies | 75 |
| January | 2, 2021 | Bulls | 99 | Suns | 87 |
| January | 4, 2021 | Warriors | 124 | Bulls | 126 |
| January | 5, 2021 | Cavaliers | 102 | Bulls | 97 |
| January | 7, 2021 | Bulls | 101 | Hornets | 88 |
| January | 14, 2021 | Bulls | 73 | Clippers | 95 |
| January | 15, 2021 | Bulls | 85 | 76ers | 99 |
| January | 16, 2021 | Knicks | 84 | Bulls | 97 |
| January | 20, 2021 | Bulls | 103 | Warriors | 86 |
| January | 22, 2021 | Grizzlies | 85 | Bulls | 117 |
| January | 26, 2021 | Bulls | 104 | Hornets | 75 |
| February | 9, 2021 | Bulls | 105 | Pistons | 110 |
| February | 10, 2021 | Celtics | 92 | Bulls | 91 |
| February | 13, 2021 | Raptors | 87 | Bulls | 98 |
| February | 14, 2021 | Bulls | 81 | Timberwolves | 88 |
| February | 15, 2021 | Bulls | 97 | 76ers | 86 |
| February | 17, 2021 | Bulls | 78 | Grizzlies | 79 |
| February | 18, 2021 | Bulls | 81 | Spurs | 87 |
| February | 25, 2021 | Bulls | 82 | Celtics | 80 |
| February | 27, 2021 | Bulls | 117 | Pistons | 120 |
| February | 28, 2021 | Bulls | 111 | Grizzlies | 83 |
| March | 2, 2021 | Bulls | 120 | 76ers | 109 |
| March | 3, 2021 | Hornets | 109 | Bulls | 115 |
| March | 12, 2021 | Celtics | 79 | Bulls | 105 |
| March | 13, 2021 | Lakers | 101 | Bulls | 119 |
| March | 15, 2021 | Bulls | 93 | Jazz | 97 |
| March | 16, 2021 | 76ers | 132 | Bulls | 130 |
| March | 18, 2021 | Bulls | 104 | Knicks | 90 |
| March | 19, 2021 | Grizzlies | 82 | Bulls | 99 |
| March | 23, 2021 | Raptors | 91 | Bulls | 95 |
| March | 24, 2021 | Spurs | 88 | Bulls | 102 |
| March | 25, 2021 | Bulls | 82 | Raptors | 83 |
| March | 28, 2021 | Pistons | 98 | Bulls | 107 |
| March | 30, 2021 | Pistons | 102 | Bulls | 110 |
| April | 4, 2021 | Knicks | 97 | Bulls | 121 |
| April | 5, 2021 | Knicks | 105 | Bulls | 124 |
| April | 7, 2021 | Bulls | 100 | Raptors | 113 |
| April | 9, 2021 | Heat | 92 | Bulls | 124 |
| April | 10, 2021 | Bulls | 99 | Knicks | 100 |
| April | 11, 2021 | Bulls | 70 | Celtics | 92 |
| April | 12, 2021 | Rockets | 78 | Bulls | 115 |
| April | 13, 2021 | Knicks | 109 | Bulls | 113 |
| April | 14, 2021 | Bulls | 92 | Heat | 116 |
| April | 17, 2021 | Suns | 59 | Bulls | 109 |
| April | 19, 2021 | Bulls | 97 | Cavaliers | 94 |
| April | 20, 2021 | Grizzlies | 86 | Bulls | 93 |
| Post | 1, 2021 | Knicks | 90 | Bulls | 105 |
| Post | 2, 2021 | Knicks | 87 | Bulls | 113 |
| Post | 3, 2021 | Bulls | 100 | Knicks | 110 |
| Post | 4, 2021 | Bulls | 111 | Knicks | 101 |
| Post | 5, 2021 | Knicks | 76 | Bulls | 106 |
| Post | 6, 2021 | Bulls | | Knicks | |
| Post | 7, 2021 | Knicks | | Bulls | |
| Post | 8, 2021 | Hornets | 104 | Bulls | 101 |
| Post | 9, 2021 | Hornets | 83 | Bulls | 105 |
| Post | 10, 2021 | Bulls | 105 | Hornets | 103 |
| Post | 11, 2021 | Bulls | 91 | Hornets | 86 |
| Post | 12, 2021 | Hornets | 95 | Bulls | 88 |
| Post | 13, 2021 | Bulls | 95 | Hornets | 101 |
| Post | 14, 2021 | Hornets | 83 | Bulls | 85 |
| Post | 15, 2021 | Bulls | 100 | Heat | 106 |
| Post | 16, 2021 | Bulls | 100 | Heat | 113 |
| Post | 17, 2021 | Heat | 107 | Bulls | 90 |
| Post | 18, 2021 | Heat | 98 | Bulls | 99 |
| Post | 19, 2021 | Bulls | 95 | Heat | 114 |
| Post | 20, 2021 | Heat | | Bulls | |
| Post | 21, 2021 | Bulls | | Heat | |