| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Grizzlies | 97 | 76ers | 123 |
| November | 4, 2020 | 76ers | 107 | Lakers | 89 |
| November | 5, 2020 | Bulls | 104 | 76ers | 116 |
| November | 7, 2020 | Suns | 97 | 76ers | 100 |
| November | 15, 2020 | Pistons | 93 | 76ers | 97 |
| November | 17, 2020 | 76ers | 91 | Bulls | 111 |
| November | 21, 2020 | 76ers | 113 | Warriors | 124 |
| November | 23, 2020 | Raptors | 102 | 76ers | 120 |
| November | 25, 2020 | Cavaliers | 93 | 76ers | 119 |
| November | 26, 2020 | Grizzlies | 104 | 76ers | 126 |
| November | 27, 2020 | Sonics | 88 | 76ers | 106 |
| November | 30, 2020 | 76ers | 102 | Celtics | 108 |
| December | 2, 2020 | 76ers | 99 | Celtics | 114 |
| December | 5, 2020 | Knicks | 110 | 76ers | 104 |
| December | 6, 2020 | 76ers | 97 | Pistons | 109 |
| December | 8, 2020 | Pistons | 106 | 76ers | 107 |
| December | 9, 2020 | 76ers | 109 | Rockets | 96 |
| December | 10, 2020 | 76ers | 108 | Pistons | 114 |
| December | 11, 2020 | Raptors | 112 | 76ers | 115 |
| December | 15, 2020 | 76ers | 118 | Bulls | 114 |
| December | 18, 2020 | 76ers | 109 | Spurs | 100 |
| December | 20, 2020 | 76ers | 103 | Hornets | 109 |
| December | 22, 2020 | Cavaliers | 106 | 76ers | 107 |
| December | 24, 2020 | Knicks | 112 | 76ers | 117 |
| December | 28, 2020 | 76ers | 94 | Knicks | 109 |
| December | 29, 2020 | Knicks | 99 | 76ers | 104 |
| December | 31, 2020 | 76ers | 99 | Cavaliers | 110 |
| January | 1, 2021 | 76ers | 106 | Heat | 146 |
| January | 4, 2021 | 76ers | 113 | Knicks | 117 |
| January | 8, 2021 | 76ers | 102 | Cavaliers | 121 |
| January | 12, 2021 | 76ers | 133 | Raptors | 123 |
| January | 14, 2021 | Lakers | 115 | 76ers | 129 |
| January | 15, 2021 | Bulls | 85 | 76ers | 99 |
| January | 18, 2021 | Jazz | 98 | 76ers | 125 |
| January | 19, 2021 | 76ers | 108 | Knicks | 126 |
| January | 22, 2021 | 76ers | 108 | Celtics | 104 |
| January | 24, 2021 | Spurs | 117 | 76ers | 116 |
| January | 27, 2021 | Warriors | 107 | 76ers | 95 |
| January | 28, 2021 | Celtics | 92 | 76ers | 119 |
| January | 29, 2021 | 76ers | 111 | Heat | 109 |
| February | 5, 2021 | 76ers | 116 | Pistons | 104 |
| February | 6, 2021 | Hornets | 111 | 76ers | 122 |
| February | 8, 2021 | 76ers | 134 | Timberwolves | 104 |
| February | 11, 2021 | Celtics | 103 | 76ers | 135 |
| February | 13, 2021 | 76ers | 112 | Suns | 108 |
| February | 14, 2021 | Pistons | 106 | 76ers | 111 |
| February | 15, 2021 | Bulls | 97 | 76ers | 86 |
| February | 17, 2021 | 76ers | 131 | Nuggets | 118 |
| February | 20, 2021 | 76ers | 94 | Cavaliers | 107 |
| February | 21, 2021 | 76ers | 119 | Heat | 116 |
| February | 26, 2021 | 76ers | 112 | Raptors | 120 |
| February | 27, 2021 | Cavaliers | 101 | 76ers | 99 |
| March | 2, 2021 | Bulls | 120 | 76ers | 109 |
| March | 4, 2021 | 76ers | 117 | Raptors | 108 |
| March | 6, 2021 | Heat | 110 | 76ers | 114 |
| March | 7, 2021 | Timberwolves | 108 | 76ers | 129 |
| March | 9, 2021 | 76ers | 113 | Hornets | 118 |
| March | 11, 2021 | Hornets | 89 | 76ers | 115 |
| March | 12, 2021 | 76ers | 124 | Grizzlies | 107 |
| March | 14, 2021 | 76ers | 111 | Hornets | 110 |
| March | 16, 2021 | 76ers | 132 | Bulls | 130 |
| March | 18, 2021 | Raptors | 99 | 76ers | 115 |
| March | 19, 2021 | 76ers | 109 | Knicks | 103 |
| March | 22, 2021 | Grizzlies | 102 | 76ers | 127 |
| March | 23, 2021 | 76ers | 111 | Sonics | 119 |
| March | 24, 2021 | 76ers | 118 | Jazz | 103 |
| March | 26, 2021 | Celtics | 116 | 76ers | 110 |
| March | 31, 2021 | Cavaliers | 103 | 76ers | 108 |
| April | 2, 2021 | Heat | 104 | 76ers | 121 |
| April | 3, 2021 | Hornets | 120 | 76ers | 123 |
| April | 4, 2021 | 76ers | 113 | Grizzlies | 102 |
| April | 6, 2021 | 76ers | 106 | Heat | 135 |
| April | 7, 2021 | 76ers | 93 | Celtics | 110 |
| April | 8, 2021 | Nuggets | 106 | 76ers | 111 |
| April | 9, 2021 | Rockets | 85 | 76ers | 121 |
| April | 10, 2021 | Clippers | 109 | 76ers | 110 |
| April | 13, 2021 | Hornets | 92 | 76ers | 114 |
| April | 14, 2021 | 76ers | 103 | Grizzlies | 84 |
| April | 15, 2021 | 76ers | 107 | Clippers | 108 |
| April | 17, 2021 | Heat | 102 | 76ers | 98 |
| April | 18, 2021 | Raptors | 106 | 76ers | 108 |
| April | 19, 2021 | 76ers | 105 | Hornets | 115 |
| Post | 1, 2021 | Hornets | 110 | 76ers | 100 |
| Post | 2, 2021 | Hornets | 82 | 76ers | 84 |
| Post | 3, 2021 | 76ers | 88 | Hornets | 98 |
| Post | 4, 2021 | 76ers | 105 | Hornets | 106 |
| Post | 5, 2021 | Hornets | 118 | 76ers | 110 |
| Post | 6, 2021 | 76ers | | Hornets | |
| Post | 7, 2021 | Hornets | | 76ers | |