| month | day | visitor | score | home | score |
|---|
| November | 6, 2017 | Pacers | 78 | Spurs | 110 |
| November | 8, 2017 | Nuggets | 88 | Spurs | 112 |
| November | 9, 2017 | Spurs | 99 | Suns | 108 |
| November | 12, 2017 | Spurs | 87 | Jazz | 86 |
| November | 14, 2017 | Wolves | 103 | Spurs | 84 |
| November | 15, 2017 | Spurs | 87 | Clippers | 90 |
| November | 17, 2017 | Spurs | 93 | Knicks | 95 |
| November | 18, 2017 | Spurs | 99 | Mavericks | 96 |
| November | 21, 2017 | Bucks | 107 | Spurs | 121 |
| November | 22, 2017 | Spurs | 107 | Blazers | 96 |
| November | 23, 2017 | Grizzlies | 82 | Spurs | 95 |
| November | 24, 2017 | Grizzlies | 79 | Spurs | 92 |
| November | 26, 2017 | 76ers | 98 | Spurs | 87 |
| November | 27, 2017 | Spurs | 99 | Kings | 126 |
| November | 28, 2017 | Spurs | 98 | Bulls | 110 |
| December | 2, 2017 | Spurs | 113 | Lakers | 107 |
| December | 4, 2017 | Spurs | 107 | Bucks | 103 |
| December | 5, 2017 | Bullets | 104 | Spurs | 99 |
| December | 6, 2017 | Spurs | 83 | Pacers | 81 |
| December | 10, 2017 | Pistons | 80 | Spurs | 111 |
| December | 12, 2017 | Spurs | 93 | Jazz | 104 |
| December | 16, 2017 | Warriors | 94 | Spurs | 117 |
| December | 17, 2017 | Celtics | | Spurs | |
| December | 18, 2017 | Spurs | | Celtics | |
| December | 19, 2017 | Spurs | | Cavaliers | |
| December | 20, 2017 | Spurs | | Nuggets | |
| December | 21, 2017 | Spurs | | Rockets | |
| December | 22, 2017 | Heat | | Spurs | |
| December | 24, 2017 | Spurs | | Sonics | |
| December | 27, 2017 | Spurs | | Suns | |
| December | 30, 2017 | Clippers | | Spurs | |
| December | 31, 2017 | Grizzlies | | Spurs | |
| January | 2, 2018 | Sonics | | Spurs | |
| January | 4, 2018 | Rockets | | Spurs | |
| January | 5, 2018 | Wolves | | Spurs | |
| January | 6, 2018 | Spurs | | Rockets | |
| January | 8, 2018 | Spurs | | 76ers | |
| January | 9, 2018 | Sonics | | Spurs | |
| January | 14, 2018 | Spurs | | Sonics | |
| January | 15, 2018 | Spurs | | Grizzlies | |
| January | 17, 2018 | Jazz | | Spurs | |
| January | 18, 2018 | Spurs | | Nets | |
| January | 19, 2018 | Spurs | | Wolves | |
| January | 20, 2018 | Kings | | Spurs | |
| January | 22, 2018 | Warriors | | Spurs | |
| January | 23, 2018 | Spurs | | Nuggets | |
| January | 25, 2018 | Cavaliers | | Spurs | |
| January | 30, 2018 | Jazz | | Spurs | |
| January | 31, 2018 | Spurs | | Wolves | |
| February | 9, 2018 | Hornets | | Spurs | |
| February | 13, 2018 | Rockets | | Spurs | |
| February | 14, 2018 | Knicks | | Spurs | |
| February | 17, 2018 | Mavericks | | Spurs | |
| February | 24, 2018 | Bulls | | Spurs | |
| February | 25, 2018 | Blazers | | Spurs | |
| February | 27, 2018 | Spurs | | Bullets | |
| March | 3, 2018 | Spurs | | Heat | |
| March | 6, 2018 | Spurs | | Magic | |
| March | 7, 2018 | Spurs | | Grizzlies | |
| March | 10, 2018 | Spurs | | Warriors | |
| March | 12, 2018 | Spurs | | Kings | |
| March | 13, 2018 | Mavericks | | Spurs | |
| March | 14, 2018 | Spurs | | Wolves | |
| March | 15, 2018 | Magic | | Spurs | |
| March | 18, 2018 | Rockets | | Spurs | |
| March | 19, 2018 | Spurs | | Mavericks | |
| March | 20, 2018 | Nuggets | | Spurs | |
| March | 22, 2018 | Suns | | Spurs | |
| March | 24, 2018 | Spurs | | Lakers | |
| March | 25, 2018 | Mavericks | | Spurs | |
| March | 26, 2018 | Spurs | | Hawks | |
| March | 27, 2018 | Spurs | | Hornets | |
| April | 2, 2018 | Spurs | | Warriors | |
| April | 6, 2018 | Spurs | | Clippers | |
| April | 7, 2018 | Suns | | Spurs | |
| April | 9, 2018 | Lakers | | Spurs | |
| April | 11, 2018 | Spurs | | Blazers | |
| April | 13, 2018 | Spurs | | Pistons | |
| April | 17, 2018 | Nets | | Spurs | |
| April | 18, 2018 | Nuggets | | Spurs | |
| April | 19, 2018 | Hawks | | Spurs | |
| April | 20, 2018 | Jazz | | Spurs | |