| month | day | visitor | score | home | score |
|---|
| November | 5, 2017 | Pacers | 76 | Pistons | 96 |
| November | 7, 2017 | Sonics | 108 | Pistons | 106 |
| November | 8, 2017 | Bulls | 118 | Pistons | 101 |
| November | 11, 2017 | Pistons | 122 | Bulls | 86 |
| November | 16, 2017 | Bulls | 130 | Pistons | 120 |
| November | 20, 2017 | Bulls | 122 | Pistons | 124 |
| November | 23, 2017 | Pistons | 108 | Cavaliers | 111 |
| November | 24, 2017 | Celtics | 101 | Pistons | 103 |
| November | 27, 2017 | Pistons | 120 | Lakers | 141 |
| November | 29, 2017 | Bullets | 106 | Pistons | 101 |
| December | 1, 2017 | Jazz | 111 | Pistons | 104 |
| December | 3, 2017 | Lakers | 123 | Pistons | 92 |
| December | 4, 2017 | Pistons | 79 | Blazers | 122 |
| December | 9, 2017 | Pistons | 92 | Nuggets | 132 |
| December | 10, 2017 | Pistons | 80 | Spurs | 111 |
| December | 13, 2017 | Pistons | 71 | Celtics | 95 |
| December | 14, 2017 | Kings | 104 | Pistons | 105 |
| December | 15, 2017 | Pistons | 93 | Clippers | 112 |
| December | 17, 2017 | Pacers | | Pistons | |
| December | 18, 2017 | Hawks | | Pistons | |
| December | 20, 2017 | Cavaliers | | Pistons | |
| December | 21, 2017 | Pistons | | Hornets | |
| December | 25, 2017 | Pacers | | Pistons | |
| December | 26, 2017 | Mavericks | | Pistons | |
| December | 27, 2017 | Grizzlies | | Pistons | |
| December | 28, 2017 | Pistons | | Celtics | |
| December | 30, 2017 | Pistons | | Bucks | |
| December | 31, 2017 | Hornets | | Pistons | |
| January | 1, 2018 | Nets | | Pistons | |
| January | 3, 2018 | Pistons | | Hawks | |
| January | 4, 2018 | Pistons | | Hawks | |
| January | 7, 2018 | Bullets | | Pistons | |
| January | 8, 2018 | Bucks | | Pistons | |
| January | 9, 2018 | Pistons | | Jazz | |
| January | 11, 2018 | Rockets | | Pistons | |
| January | 14, 2018 | Pistons | | Pacers | |
| January | 15, 2018 | Clippers | | Pistons | |
| January | 17, 2018 | Nets | | Pistons | |
| January | 18, 2018 | Blazers | | Pistons | |
| January | 20, 2018 | Wolves | | Pistons | |
| January | 21, 2018 | Pistons | | Rockets | |
| January | 22, 2018 | Pistons | | Bucks | |
| January | 24, 2018 | Cavaliers | | Pistons | |
| January | 27, 2018 | Knicks | | Pistons | |
| January | 28, 2018 | Hornets | | Pistons | |
| January | 29, 2018 | Pistons | | Bullets | |
| January | 31, 2018 | Pistons | | Grizzlies | |
| February | 5, 2018 | Nuggets | | Pistons | |
| February | 7, 2018 | Pistons | | Heat | |
| February | 8, 2018 | Magic | | Pistons | |
| February | 9, 2018 | Cavaliers | | Pistons | |
| February | 10, 2018 | Pistons | | Magic | |
| February | 11, 2018 | Pistons | | Heat | |
| February | 13, 2018 | Pistons | | Knicks | |
| February | 15, 2018 | Bucks | | Pistons | |
| February | 18, 2018 | Pistons | | Sonics | |
| February | 21, 2018 | Hawks | | Pistons | |
| February | 24, 2018 | Hawks | | Pistons | |
| February | 26, 2018 | Suns | | Pistons | |
| February | 28, 2018 | Pistons | | Suns | |
| March | 5, 2018 | Pistons | | Nets | |
| March | 6, 2018 | Pistons | | Wolves | |
| March | 8, 2018 | 76ers | | Pistons | |
| March | 9, 2018 | Bucks | | Pistons | |
| March | 11, 2018 | Heat | | Pistons | |
| March | 12, 2018 | Pistons | | 76ers | |
| March | 17, 2018 | Pistons | | Hornets | |
| March | 22, 2018 | Pistons | | Knicks | |
| March | 24, 2018 | Warriors | | Pistons | |
| March | 25, 2018 | Pistons | | 76ers | |
| March | 28, 2018 | Hornets | | Pistons | |
| March | 29, 2018 | Pistons | | Kings | |
| March | 30, 2018 | Pistons | | Bulls | |
| April | 1, 2018 | Pistons | | Magic | |
| April | 3, 2018 | Pistons | | Nets | |
| April | 7, 2018 | Pistons | | Mavericks | |
| April | 9, 2018 | Pistons | | Pacers | |
| April | 10, 2018 | Pistons | | Bullets | |
| April | 12, 2018 | Pistons | | Cavaliers | |
| April | 13, 2018 | Spurs | | Pistons | |
| April | 14, 2018 | Pistons | | Bucks | |
| April | 15, 2018 | Pistons | | Warriors | |