| month | day | visitor | score | home | score |
|---|
| November | 2, 2017 | Cavaliers | 92 | Rockets | 103 |
| November | 4, 2017 | Cavaliers | 71 | Heat | 72 |
| November | 8, 2017 | Clippers | 88 | Cavaliers | 74 |
| November | 13, 2017 | Mavericks | 82 | Cavaliers | 83 |
| November | 14, 2017 | Cavaliers | 93 | Kings | 110 |
| November | 16, 2017 | Hawks | 76 | Cavaliers | 83 |
| November | 17, 2017 | Celtics | 111 | Cavaliers | 104 |
| November | 18, 2017 | Cavaliers | 119 | Bulls | 106 |
| November | 19, 2017 | Cavaliers | 79 | Bullets | 124 |
| November | 21, 2017 | Cavaliers | 99 | Hornets | 115 |
| November | 23, 2017 | Pistons | 108 | Cavaliers | 111 |
| November | 29, 2017 | Sonics | 113 | Cavaliers | 112 |
| November | 30, 2017 | Rockets | 88 | Cavaliers | 125 |
| December | 1, 2017 | Hornets | 94 | Cavaliers | 107 |
| December | 3, 2017 | Heat | 63 | Cavaliers | 96 |
| December | 5, 2017 | Knicks | 90 | Cavaliers | 116 |
| December | 7, 2017 | Nets | 81 | Cavaliers | 124 |
| December | 8, 2017 | Pacers | 80 | Cavaliers | 117 |
| December | 9, 2017 | Wolves | 52 | Cavaliers | 103 |
| December | 11, 2017 | Cavaliers | 96 | 76ers | 94 |
| December | 13, 2017 | Cavaliers | 105 | Blazers | 110 |
| December | 15, 2017 | Bullets | 101 | Cavaliers | 114 |
| December | 17, 2017 | Cavaliers | | Nets | |
| December | 19, 2017 | Spurs | | Cavaliers | |
| December | 20, 2017 | Cavaliers | | Pistons | |
| December | 24, 2017 | Cavaliers | | Celtics | |
| December | 25, 2017 | Cavaliers | | Knicks | |
| December | 26, 2017 | Cavaliers | | Celtics | |
| January | 3, 2018 | 76ers | | Cavaliers | |
| January | 4, 2018 | Bulls | | Cavaliers | |
| January | 6, 2018 | Bucks | | Cavaliers | |
| January | 10, 2018 | Cavaliers | | Nuggets | |
| January | 11, 2018 | Cavaliers | | Mavericks | |
| January | 12, 2018 | Kings | | Cavaliers | |
| January | 16, 2018 | Magic | | Cavaliers | |
| January | 17, 2018 | Hawks | | Cavaliers | |
| January | 21, 2018 | Cavaliers | | Pacers | |
| January | 22, 2018 | Cavaliers | | Hawks | |
| January | 24, 2018 | Cavaliers | | Pistons | |
| January | 25, 2018 | Cavaliers | | Spurs | |
| January | 27, 2018 | Cavaliers | | Bucks | |
| January | 28, 2018 | Cavaliers | | Warriors | |
| January | 30, 2018 | Heat | | Cavaliers | |
| February | 5, 2018 | Cavaliers | | Lakers | |
| February | 9, 2018 | Cavaliers | | Pistons | |
| February | 12, 2018 | Cavaliers | | Pacers | |
| February | 18, 2018 | Knicks | | Cavaliers | |
| February | 19, 2018 | Cavaliers | | Heat | |
| February | 20, 2018 | Pacers | | Cavaliers | |
| February | 22, 2018 | Blazers | | Cavaliers | |
| February | 25, 2018 | Nets | | Cavaliers | |
| February | 26, 2018 | Hornets | | Cavaliers | |
| March | 1, 2018 | Cavaliers | | Jazz | |
| March | 2, 2018 | Cavaliers | | Bucks | |
| March | 3, 2018 | Warriors | | Cavaliers | |
| March | 4, 2018 | Magic | | Cavaliers | |
| March | 5, 2018 | Suns | | Cavaliers | |
| March | 9, 2018 | Grizzlies | | Cavaliers | |
| March | 11, 2018 | Cavaliers | | Hawks | |
| March | 13, 2018 | Cavaliers | | Sonics | |
| March | 14, 2018 | Cavaliers | | Suns | |
| March | 15, 2018 | Nuggets | | Cavaliers | |
| March | 16, 2018 | Cavaliers | | Clippers | |
| March | 20, 2018 | Cavaliers | | Hawks | |
| March | 21, 2018 | Bulls | | Cavaliers | |
| March | 23, 2018 | Bulls | | Cavaliers | |
| March | 24, 2018 | Bullets | | Cavaliers | |
| March | 25, 2018 | Cavaliers | | Hornets | |
| March | 28, 2018 | Cavaliers | | Grizzlies | |
| March | 29, 2018 | Cavaliers | | Pacers | |
| April | 3, 2018 | Celtics | | Cavaliers | |
| April | 5, 2018 | Cavaliers | | Knicks | |
| April | 6, 2018 | Cavaliers | | Magic | |
| April | 7, 2018 | Bucks | | Cavaliers | |
| April | 8, 2018 | Bucks | | Cavaliers | |
| April | 10, 2018 | Cavaliers | | 76ers | |
| April | 11, 2018 | Jazz | | Cavaliers | |
| April | 12, 2018 | Pistons | | Cavaliers | |
| April | 14, 2018 | Cavaliers | | Hornets | |
| April | 15, 2018 | Cavaliers | | Wolves | |
| April | 16, 2018 | Cavaliers | | Bulls | |
| April | 20, 2018 | Lakers | | Cavaliers | |