| month | day | visitor | score | home | score |
|---|
| November | 4, 2018 | Knicks | | Spurs | |
| November | 5, 2018 | Spurs | | Heat | |
| November | 10, 2018 | Spurs | | Wolves | |
| November | 13, 2018 | Lakers | | Spurs | |
| November | 15, 2018 | Rockets | | Spurs | |
| November | 18, 2018 | Spurs | | Mavericks | |
| November | 19, 2018 | Grizzlies | | Spurs | |
| November | 22, 2018 | Jazz | | Spurs | |
| November | 27, 2018 | Jazz | | Spurs | |
| November | 29, 2018 | Suns | | Spurs | |
| December | 5, 2018 | Jazz | | Spurs | |
| December | 6, 2018 | Spurs | | Clippers | |
| December | 7, 2018 | Bucks | | Spurs | |
| December | 8, 2018 | Wolves | | Spurs | |
| December | 10, 2018 | Nuggets | | Spurs | |
| December | 11, 2018 | Warriors | | Spurs | |
| December | 13, 2018 | Hawks | | Spurs | |
| December | 15, 2018 | Spurs | | Celtics | |
| December | 17, 2018 | Spurs | | Rockets | |
| December | 20, 2018 | Spurs | | Mavericks | |
| December | 21, 2018 | Spurs | | Pelicans | |
| December | 22, 2018 | Mavericks | | Spurs | |
| December | 23, 2018 | Pacers | | Spurs | |
| December | 31, 2018 | Kings | | Spurs | |
| January | 1, 2019 | Blazers | | Spurs | |
| January | 2, 2019 | Nets | | Spurs | |
| January | 3, 2019 | Spurs | | Kings | |
| January | 5, 2019 | Lakers | | Spurs | |
| January | 7, 2019 | Spurs | | Sonics | |
| January | 8, 2019 | Sonics | | Spurs | |
| January | 9, 2019 | Spurs | | Clippers | |
| January | 11, 2019 | Clippers | | Spurs | |
| January | 14, 2019 | Spurs | | Wolves | |
| January | 17, 2019 | Spurs | | Mavericks | |
| January | 20, 2019 | Mavericks | | Spurs | |
| January | 21, 2019 | Clippers | | Spurs | |
| January | 25, 2019 | Spurs | | Bulls | |
| January | 27, 2019 | Spurs | | Jazz | |
| January | 28, 2019 | Blazers | | Spurs | |
| January | 29, 2019 | Spurs | | Bucks | |
| February | 1, 2019 | Kings | | Spurs | |
| February | 2, 2019 | Spurs | | Nuggets | |
| February | 4, 2019 | Heat | | Spurs | |
| February | 9, 2019 | Spurs | | Jazz | |
| February | 11, 2019 | Pelicans | | Spurs | |
| February | 12, 2019 | Warriors | | Spurs | |
| February | 13, 2019 | Spurs | | Kings | |
| February | 15, 2019 | Spurs | | Rockets | |
| February | 16, 2019 | Bulls | | Spurs | |
| February | 21, 2019 | Spurs | | Nuggets | |
| February | 24, 2019 | Wolves | | Spurs | |
| February | 26, 2019 | Spurs | | Hawks | |
| February | 28, 2019 | 76ers | | Spurs | |
| March | 2, 2019 | Spurs | | Knicks | |
| March | 3, 2019 | Spurs | | Sonics | |
| March | 4, 2019 | Spurs | | Nuggets | |
| March | 6, 2019 | Rockets | | Spurs | |
| March | 8, 2019 | Spurs | | Suns | |
| March | 9, 2019 | Spurs | | Lakers | |
| March | 11, 2019 | Sonics | | Spurs | |
| March | 12, 2019 | Spurs | | Lakers | |
| March | 15, 2019 | Mavericks | | Spurs | |
| March | 21, 2019 | Celtics | | Spurs | |
| March | 23, 2019 | Spurs | | Warriors | |
| March | 27, 2019 | Spurs | | Nets | |
| March | 29, 2019 | Spurs | | Grizzlies | |
| March | 30, 2019 | Spurs | | Suns | |
| April | 1, 2019 | Rockets | | Spurs | |
| April | 3, 2019 | Spurs | | Wolves | |
| April | 4, 2019 | Raptors | | Spurs | |
| April | 7, 2019 | Suns | | Spurs | |
| April | 8, 2019 | Spurs | | 76ers | |
| April | 9, 2019 | Spurs | | Warriors | |
| April | 10, 2019 | Nuggets | | Spurs | |
| April | 11, 2019 | Spurs | | Blazers | |
| April | 12, 2019 | Spurs | | Jazz | |
| April | 13, 2019 | Wolves | | Spurs | |
| April | 14, 2019 | Spurs | | Raptors | |
| April | 16, 2019 | Spurs | | Suns | |
| April | 22, 2019 | Spurs | | Blazers | |
| April | 24, 2019 | Spurs | | Pacers | |
| April | 25, 2019 | Nuggets | | Spurs | |