| month | day | visitor | score | home | score |
|---|
| November | 4, 2022 | Knicks | 94 | Spurs | 88 |
| November | 5, 2022 | Spurs | 84 | Heat | 95 |
| November | 10, 2022 | Spurs | 99 | Wolves | 114 |
| November | 13, 2022 | Lakers | 93 | Spurs | 99 |
| November | 15, 2022 | Rockets | 103 | Spurs | 79 |
| November | 18, 2022 | Spurs | 88 | Mavericks | 123 |
| November | 19, 2022 | Grizzlies | 96 | Spurs | 100 |
| November | 22, 2022 | Jazz | 110 | Spurs | 96 |
| November | 27, 2022 | Jazz | 105 | Spurs | 116 |
| November | 29, 2022 | Suns | 92 | Spurs | 84 |
| December | 5, 2022 | Jazz | 121 | Spurs | 97 |
| December | 6, 2022 | Spurs | 101 | Clippers | 113 |
| December | 7, 2022 | Bucks | 117 | Spurs | 111 |
| December | 8, 2022 | Wolves | 116 | Spurs | 119 |
| December | 10, 2022 | Nuggets | 110 | Spurs | 107 |
| December | 11, 2022 | Warriors | 72 | Spurs | 93 |
| December | 13, 2022 | Hawks | 126 | Spurs | 100 |
| December | 15, 2022 | Spurs | 108 | Celtics | 121 |
| December | 17, 2022 | Spurs | | Rockets | |
| December | 20, 2022 | Spurs | | Mavericks | |
| December | 21, 2022 | Spurs | | Pelicans | |
| December | 22, 2022 | Mavericks | | Spurs | |
| December | 23, 2022 | Pacers | | Spurs | |
| December | 31, 2022 | Kings | | Spurs | |
| January | 1, 2023 | Blazers | | Spurs | |
| January | 2, 2023 | Nets | | Spurs | |
| January | 3, 2023 | Spurs | | Kings | |
| January | 5, 2023 | Lakers | | Spurs | |
| January | 7, 2023 | Spurs | | Sonics | |
| January | 8, 2023 | Sonics | | Spurs | |
| January | 9, 2023 | Spurs | | Clippers | |
| January | 11, 2023 | Clippers | | Spurs | |
| January | 14, 2023 | Spurs | | Wolves | |
| January | 17, 2023 | Spurs | | Mavericks | |
| January | 20, 2023 | Mavericks | | Spurs | |
| January | 21, 2023 | Clippers | | Spurs | |
| January | 25, 2023 | Spurs | | Bulls | |
| January | 27, 2023 | Spurs | | Jazz | |
| January | 28, 2023 | Blazers | | Spurs | |
| January | 29, 2023 | Spurs | | Bucks | |
| February | 1, 2023 | Kings | | Spurs | |
| February | 2, 2023 | Spurs | | Nuggets | |
| February | 4, 2023 | Heat | | Spurs | |
| February | 9, 2023 | Spurs | | Jazz | |
| February | 11, 2023 | Pelicans | | Spurs | |
| February | 12, 2023 | Warriors | | Spurs | |
| February | 13, 2023 | Spurs | | Kings | |
| February | 15, 2023 | Spurs | | Rockets | |
| February | 16, 2023 | Bulls | | Spurs | |
| February | 21, 2023 | Spurs | | Nuggets | |
| February | 24, 2023 | Wolves | | Spurs | |
| February | 26, 2023 | Spurs | | Hawks | |
| February | 28, 2023 | 76ers | | Spurs | |
| March | 2, 2023 | Spurs | | Knicks | |
| March | 3, 2023 | Spurs | | Sonics | |
| March | 4, 2023 | Spurs | | Nuggets | |
| March | 6, 2023 | Rockets | | Spurs | |
| March | 8, 2023 | Spurs | | Suns | |
| March | 9, 2023 | Spurs | | Lakers | |
| March | 11, 2023 | Sonics | | Spurs | |
| March | 12, 2023 | Spurs | | Lakers | |
| March | 15, 2023 | Mavericks | | Spurs | |
| March | 21, 2023 | Celtics | | Spurs | |
| March | 23, 2023 | Spurs | | Warriors | |
| March | 27, 2023 | Spurs | | Nets | |
| March | 29, 2023 | Spurs | | Grizzlies | |
| March | 30, 2023 | Spurs | | Suns | |
| April | 1, 2023 | Rockets | | Spurs | |
| April | 3, 2023 | Spurs | | Wolves | |
| April | 4, 2023 | Raptors | | Spurs | |
| April | 7, 2023 | Suns | | Spurs | |
| April | 8, 2023 | Spurs | | 76ers | |
| April | 9, 2023 | Spurs | | Warriors | |
| April | 10, 2023 | Nuggets | | Spurs | |
| April | 11, 2023 | Spurs | | Blazers | |
| April | 12, 2023 | Spurs | | Jazz | |
| April | 13, 2023 | Wolves | | Spurs | |
| April | 14, 2023 | Spurs | | Raptors | |
| April | 16, 2023 | Spurs | | Suns | |
| April | 22, 2023 | Spurs | | Blazers | |
| April | 24, 2023 | Spurs | | Pacers | |
| April | 25, 2023 | Nuggets | | Spurs | |