| month | day | visitor | score | home | score |
|---|
| November | 3, 2021 | Nuggets | 129 | Grizzlies | 98 |
| November | 4, 2021 | Nuggets | 108 | Wolves | 105 |
| November | 5, 2021 | Nuggets | 97 | Raptors | 114 |
| November | 6, 2021 | Nuggets | 112 | Suns | 93 |
| November | 12, 2021 | Lakers | 120 | Nuggets | 123 |
| November | 13, 2021 | Nuggets | 119 | Wolves | 97 |
| November | 15, 2021 | Nuggets | 117 | Jazz | 124 |
| November | 18, 2021 | Sonics | 76 | Nuggets | 123 |
| November | 20, 2021 | Rockets | 120 | Nuggets | 142 |
| November | 21, 2021 | Nuggets | 95 | Clippers | 128 |
| November | 26, 2021 | Mavericks | 110 | Nuggets | 109 |
| December | 1, 2021 | Rockets | 103 | Nuggets | 109 |
| December | 2, 2021 | Nuggets | 115 | Suns | 106 |
| December | 3, 2021 | 76ers | 109 | Nuggets | 125 |
| December | 5, 2021 | Nuggets | 104 | Mavericks | 100 |
| December | 10, 2021 | Nuggets | 122 | Spurs | 100 |
| December | 13, 2021 | Nuggets | 134 | Celtics | 143 |
| December | 15, 2021 | Jazz | 108 | Nuggets | 134 |
| December | 16, 2021 | Nuggets | 98 | Blazers | 103 |
| December | 23, 2021 | Suns | 113 | Nuggets | 102 |
| December | 24, 2021 | Nuggets | 98 | Kings | 85 |
| December | 27, 2021 | Pacers | 104 | Nuggets | 119 |
| December | 30, 2021 | Nuggets | 94 | Jazz | 121 |
| January | 3, 2022 | Nuggets | 109 | Rockets | 99 |
| January | 6, 2022 | Sonics | 120 | Nuggets | 116 |
| January | 7, 2022 | Nuggets | 102 | Hawks | 110 |
| January | 9, 2022 | Nuggets | 110 | Sonics | 103 |
| January | 12, 2022 | Suns | 120 | Nuggets | 113 |
| January | 13, 2022 | Kings | 95 | Nuggets | 86 |
| January | 14, 2022 | Nuggets | 101 | Rockets | 98 |
| January | 18, 2022 | Knicks | 123 | Nuggets | 115 |
| January | 20, 2022 | Lakers | 109 | Nuggets | 111 |
| January | 22, 2022 | Nuggets | 121 | Suns | 114 |
| January | 27, 2022 | Nuggets | 131 | Blazers | 114 |
| January | 29, 2022 | Nuggets | 111 | Mavericks | 136 |
| January | 31, 2022 | Mavericks | 119 | Nuggets | 97 |
| February | 2, 2022 | Spurs | | Nuggets | |
| February | 4, 2022 | Blazers | | Nuggets | |
| February | 8, 2022 | Nuggets | | Lakers | |
| February | 9, 2022 | Bulls | | Nuggets | |
| February | 13, 2022 | Mavericks | | Nuggets | |
| February | 17, 2022 | Nuggets | | Knicks | |
| February | 18, 2022 | Pelicans | | Nuggets | |
| February | 19, 2022 | Nets | | Nuggets | |
| February | 21, 2022 | Spurs | | Nuggets | |
| February | 22, 2022 | Wolves | | Nuggets | |
| February | 23, 2022 | Raptors | | Nuggets | |
| February | 25, 2022 | Nuggets | | Heat | |
| February | 27, 2022 | Clippers | | Nuggets | |
| March | 1, 2022 | Blazers | | Nuggets | |
| March | 3, 2022 | Wolves | | Nuggets | |
| March | 4, 2022 | Spurs | | Nuggets | |
| March | 5, 2022 | Nuggets | | Kings | |
| March | 8, 2022 | Nuggets | | Jazz | |
| March | 11, 2022 | Clippers | | Nuggets | |
| March | 13, 2022 | Nuggets | | Warriors | |
| March | 15, 2022 | Nuggets | | Pelicans | |
| March | 17, 2022 | Nuggets | | Bucks | |
| March | 19, 2022 | Nuggets | | Lakers | |
| March | 20, 2022 | Nuggets | | Rockets | |
| March | 21, 2022 | Grizzlies | | Nuggets | |
| March | 22, 2022 | Celtics | | Nuggets | |
| March | 24, 2022 | Nuggets | | Wolves | |
| March | 26, 2022 | Suns | | Nuggets | |
| March | 27, 2022 | Nuggets | | Warriors | |
| March | 29, 2022 | Bucks | | Nuggets | |
| March | 30, 2022 | Jazz | | Nuggets | |
| March | 31, 2022 | Nuggets | | Bulls | |
| April | 1, 2022 | Nuggets | | Clippers | |
| April | 2, 2022 | Warriors | | Nuggets | |
| April | 3, 2022 | Nuggets | | Sonics | |
| April | 4, 2022 | Wolves | | Nuggets | |
| April | 7, 2022 | Kings | | Nuggets | |
| April | 8, 2022 | Nuggets | | Pacers | |
| April | 10, 2022 | Nuggets | | Spurs | |
| April | 12, 2022 | Heat | | Nuggets | |
| April | 13, 2022 | Warriors | | Nuggets | |
| April | 15, 2022 | Nuggets | | Nets | |
| April | 16, 2022 | Nuggets | | 76ers | |
| April | 17, 2022 | Jazz | | Nuggets | |
| April | 24, 2022 | Hawks | | Nuggets | |
| April | 25, 2022 | Nuggets | | Spurs | |