| month | day | visitor | score | home | score |
|---|
| November | 4, 2020 | Nuggets | 112 | Wolves | 121 |
| November | 6, 2020 | Grizzlies | 80 | Wolves | 108 |
| November | 8, 2020 | Wolves | 109 | Clippers | 99 |
| November | 10, 2020 | Spurs | 108 | Wolves | 113 |
| November | 12, 2020 | Kings | 94 | Wolves | 121 |
| November | 13, 2020 | Nuggets | 103 | Wolves | 99 |
| November | 14, 2020 | Lakers | 118 | Wolves | 116 |
| November | 16, 2020 | Wolves | 103 | Rockets | 109 |
| November | 19, 2020 | Bulls | 99 | Wolves | 105 |
| November | 21, 2020 | Wolves | 99 | Raptors | 108 |
| November | 22, 2020 | Wolves | 119 | Nets | 112 |
| November | 23, 2020 | Rockets | 95 | Wolves | 98 |
| November | 25, 2020 | Wolves | 108 | Kings | 119 |
| November | 27, 2020 | Mavericks | 93 | Wolves | 84 |
| November | 28, 2020 | Suns | 74 | Wolves | 123 |
| November | 30, 2020 | Wolves | 97 | Sonics | 121 |
| December | 4, 2020 | Warriors | 84 | Wolves | 109 |
| December | 6, 2020 | Wolves | 109 | Warriors | 121 |
| December | 8, 2020 | Wolves | 89 | Spurs | 92 |
| December | 9, 2020 | Wolves | 128 | Grizzlies | 110 |
| December | 15, 2020 | Clippers | 94 | Wolves | 105 |
| December | 16, 2020 | Wolves | 103 | Pelicans | 106 |
| December | 19, 2020 | Bucks | 97 | Wolves | 120 |
| December | 20, 2020 | Blazers | 126 | Wolves | 121 |
| December | 23, 2020 | Raptors | 129 | Wolves | 141 |
| January | 4, 2021 | Wolves | 77 | Celtics | 104 |
| January | 8, 2021 | 76ers | 92 | Wolves | 86 |
| January | 13, 2021 | Mavericks | 82 | Wolves | 102 |
| January | 14, 2021 | Spurs | 77 | Wolves | 84 |
| January | 18, 2021 | Sonics | 116 | Wolves | 112 |
| January | 19, 2021 | Wolves | 90 | Blazers | 118 |
| January | 20, 2021 | Wolves | 93 | Jazz | 98 |
| January | 21, 2021 | Wolves | 101 | Blazers | 132 |
| January | 23, 2021 | Wolves | 93 | 76ers | 103 |
| January | 24, 2021 | Suns | 110 | Wolves | 84 |
| January | 25, 2021 | Hawks | 98 | Wolves | 95 |
| January | 27, 2021 | Wolves | 65 | Bucks | 106 |
| January | 28, 2021 | Wolves | 74 | Jazz | 98 |
| January | 29, 2021 | Wolves | 97 | Bulls | 117 |
| January | 30, 2021 | Celtics | 105 | Wolves | 89 |
| January | 31, 2021 | Jazz | 113 | Wolves | 90 |
| February | 2, 2021 | Mavericks | | Wolves | |
| February | 11, 2021 | Wolves | | Jazz | |
| February | 18, 2021 | Wolves | | Knicks | |
| February | 22, 2021 | Wolves | | Nuggets | |
| February | 23, 2021 | Wolves | | Mavericks | |
| February | 24, 2021 | Wolves | | Spurs | |
| February | 26, 2021 | Rockets | | Wolves | |
| February | 27, 2021 | Wolves | | Warriors | |
| February | 28, 2021 | Wolves | | Suns | |
| March | 2, 2021 | Wolves | | Lakers | |
| March | 3, 2021 | Wolves | | Nuggets | |
| March | 10, 2021 | Wolves | | Mavericks | |
| March | 14, 2021 | Wolves | | Rockets | |
| March | 15, 2021 | Kings | | Wolves | |
| March | 17, 2021 | Suns | | Wolves | |
| March | 20, 2021 | Wolves | | Mavericks | |
| March | 24, 2021 | Nuggets | | Wolves | |
| March | 25, 2021 | Wolves | | Hawks | |
| March | 26, 2021 | Pacers | | Wolves | |
| March | 27, 2021 | Wolves | | Lakers | |
| March | 29, 2021 | Jazz | | Wolves | |
| March | 31, 2021 | Wolves | | Rockets | |
| April | 1, 2021 | Blazers | | Wolves | |
| April | 3, 2021 | Spurs | | Wolves | |
| April | 4, 2021 | Wolves | | Nuggets | |
| April | 5, 2021 | Heat | | Wolves | |
| April | 6, 2021 | Jazz | | Wolves | |
| April | 7, 2021 | Rockets | | Wolves | |
| April | 12, 2021 | Wolves | | Clippers | |
| April | 13, 2021 | Wolves | | Spurs | |
| April | 14, 2021 | Wolves | | Kings | |
| April | 15, 2021 | Wolves | | Heat | |
| April | 16, 2021 | Clippers | | Wolves | |
| April | 17, 2021 | Knicks | | Wolves | |
| April | 18, 2021 | Wolves | | Pacers | |
| April | 19, 2021 | Pelicans | | Wolves | |
| April | 20, 2021 | Warriors | | Wolves | |
| April | 21, 2021 | Lakers | | Wolves | |
| April | 22, 2021 | Wolves | | Suns | |
| April | 24, 2021 | Wolves | | Sonics | |
| April | 26, 2021 | Nets | | Wolves | |