| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Raptors | 97 | Mavericks | 108 |
| November | 3, 2020 | Hawks | 94 | Raptors | 125 |
| November | 5, 2020 | Nuggets | 119 | Raptors | 115 |
| November | 6, 2020 | Celtics | 118 | Raptors | 116 |
| November | 8, 2020 | Sonics | 98 | Raptors | 117 |
| November | 9, 2020 | Raptors | 130 | Hawks | 128 |
| November | 11, 2020 | Raptors | 104 | Nets | 98 |
| November | 13, 2020 | Raptors | 113 | Pacers | 98 |
| November | 14, 2020 | Raptors | 125 | Celtics | 121 |
| November | 16, 2020 | Raptors | 108 | Pacers | 113 |
| November | 17, 2020 | Raptors | 123 | Knicks | 99 |
| November | 19, 2020 | Raptors | 111 | Pacers | 92 |
| November | 20, 2020 | Raptors | 100 | Bulls | 81 |
| November | 21, 2020 | Wolves | 99 | Raptors | 108 |
| November | 23, 2020 | Raptors | 123 | Warriors | 117 |
| November | 24, 2020 | Raptors | 107 | Celtics | 113 |
| November | 27, 2020 | Raptors | 101 | Rockets | 107 |
| November | 29, 2020 | Jazz | 111 | Raptors | 105 |
| December | 1, 2020 | Raptors | 105 | Heat | 126 |
| December | 4, 2020 | Raptors | 116 | Hawks | 105 |
| December | 8, 2020 | Warriors | 96 | Raptors | 142 |
| December | 9, 2020 | Bulls | 93 | Raptors | 114 |
| December | 10, 2020 | Raptors | 112 | Blazers | 138 |
| December | 12, 2020 | Lakers | 117 | Raptors | 130 |
| December | 14, 2020 | Knicks | 127 | Raptors | 107 |
| December | 18, 2020 | Raptors | 119 | Grizzlies | 90 |
| December | 19, 2020 | Hawks | 103 | Raptors | 113 |
| December | 21, 2020 | Raptors | 102 | 76ers | 97 |
| December | 22, 2020 | Bucks | 111 | Raptors | 128 |
| December | 23, 2020 | Raptors | 129 | Wolves | 141 |
| December | 24, 2020 | Grizzlies | 101 | Raptors | 114 |
| December | 26, 2020 | Raptors | 113 | Knicks | 96 |
| December | 27, 2020 | Raptors | 114 | Bucks | 118 |
| December | 28, 2020 | Clippers | 86 | Raptors | 130 |
| January | 4, 2021 | Knicks | 100 | Raptors | 115 |
| January | 7, 2021 | Nets | 102 | Raptors | 117 |
| January | 12, 2021 | Raptors | 108 | Bucks | 98 |
| January | 14, 2021 | Raptors | 113 | Grizzlies | 107 |
| January | 16, 2021 | Raptors | 101 | Lakers | 74 |
| January | 18, 2021 | Heat | 95 | Raptors | 131 |
| January | 22, 2021 | Pacers | 85 | Raptors | 103 |
| January | 26, 2021 | Kings | 111 | Raptors | 126 |
| January | 29, 2021 | Raptors | 128 | Clippers | 100 |
| January | 31, 2021 | Raptors | 109 | Nets | 105 |
| February | 1, 2021 | Rockets | | Raptors | |
| February | 2, 2021 | Pelicans | | Raptors | |
| February | 4, 2021 | Raptors | | Hawks | |
| February | 8, 2021 | 76ers | | Raptors | |
| February | 10, 2021 | Nets | | Raptors | |
| February | 11, 2021 | Raptors | | 76ers | |
| February | 12, 2021 | Bulls | | Raptors | |
| February | 14, 2021 | Grizzlies | | Raptors | |
| February | 15, 2021 | Mavericks | | Raptors | |
| February | 16, 2021 | Suns | | Raptors | |
| February | 19, 2021 | Celtics | | Raptors | |
| February | 20, 2021 | Hawks | | Raptors | |
| February | 23, 2021 | Raptors | | Nuggets | |
| February | 24, 2021 | Raptors | | Kings | |
| March | 1, 2021 | Pacers | | Raptors | |
| March | 2, 2021 | Raptors | | Suns | |
| March | 4, 2021 | Raptors | | Bulls | |
| March | 5, 2021 | Pelicans | | Raptors | |
| March | 6, 2021 | Raptors | | Sonics | |
| March | 9, 2021 | Bucks | | Raptors | |
| March | 10, 2021 | Pacers | | Raptors | |
| March | 13, 2021 | Blazers | | Raptors | |
| March | 14, 2021 | Raptors | | Grizzlies | |
| March | 16, 2021 | Raptors | | 76ers | |
| March | 17, 2021 | Raptors | | Jazz | |
| March | 18, 2021 | Grizzlies | | Raptors | |
| March | 22, 2021 | Raptors | | Heat | |
| March | 24, 2021 | Pacers | | Raptors | |
| March | 25, 2021 | Bucks | | Raptors | |
| March | 26, 2021 | Heat | | Raptors | |
| March | 31, 2021 | 76ers | | Raptors | |
| April | 4, 2021 | Raptors | | Spurs | |
| April | 5, 2021 | Raptors | | Pelicans | |
| April | 14, 2021 | Spurs | | Raptors | |
| April | 15, 2021 | Raptors | | Bulls | |
| April | 20, 2021 | Raptors | | Pelicans | |
| April | 23, 2021 | Raptors | | Bucks | |
| April | 24, 2021 | Bulls | | Raptors | |