| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Raptors | 97 | Mavericks | 108 |
| November | 5, 2020 | Mavericks | 106 | Warriors | 94 |
| November | 8, 2020 | Jazz | 103 | Mavericks | 101 |
| November | 11, 2020 | Mavericks | 103 | Bucks | 90 |
| November | 12, 2020 | Mavericks | 121 | Blazers | 112 |
| November | 14, 2020 | Mavericks | 104 | Kings | 98 |
| November | 15, 2020 | Hawks | 95 | Mavericks | 127 |
| November | 18, 2020 | Spurs | 76 | Mavericks | 108 |
| November | 20, 2020 | Mavericks | 110 | Kings | 95 |
| November | 24, 2020 | Mavericks | 101 | Rockets | 95 |
| November | 25, 2020 | Mavericks | 95 | Pacers | 66 |
| November | 26, 2020 | Mavericks | 122 | Nuggets | 117 |
| November | 27, 2020 | Mavericks | 93 | Wolves | 84 |
| November | 28, 2020 | Mavericks | 88 | Celtics | 99 |
| December | 3, 2020 | Warriors | 117 | Mavericks | 108 |
| December | 5, 2020 | Nuggets | 85 | Mavericks | 112 |
| December | 10, 2020 | Mavericks | 86 | Suns | 87 |
| December | 14, 2020 | Mavericks | 96 | Hawks | 102 |
| December | 16, 2020 | Mavericks | 112 | Jazz | 97 |
| December | 18, 2020 | Clippers | 89 | Mavericks | 117 |
| December | 19, 2020 | Mavericks | 107 | Clippers | 98 |
| December | 20, 2020 | Spurs | 101 | Mavericks | 103 |
| December | 21, 2020 | Mavericks | 93 | Nets | 100 |
| December | 22, 2020 | Mavericks | 80 | Spurs | 95 |
| December | 27, 2020 | Blazers | 102 | Mavericks | 111 |
| December | 28, 2020 | Blazers | 123 | Mavericks | 128 |
| December | 30, 2020 | Mavericks | 91 | Clippers | 115 |
| December | 31, 2020 | Mavericks | 82 | Rockets | 110 |
| January | 1, 2021 | Mavericks | 107 | Suns | 105 |
| January | 4, 2021 | Bucks | 88 | Mavericks | 100 |
| January | 5, 2021 | Bulls | 106 | Mavericks | 103 |
| January | 7, 2021 | Mavericks | 88 | 76ers | 105 |
| January | 9, 2021 | Mavericks | 77 | Jazz | 92 |
| January | 13, 2021 | Mavericks | 82 | Wolves | 102 |
| January | 14, 2021 | Lakers | 86 | Mavericks | 90 |
| January | 15, 2021 | Mavericks | 78 | Rockets | 91 |
| January | 16, 2021 | Jazz | 70 | Mavericks | 92 |
| January | 17, 2021 | Spurs | 87 | Mavericks | 109 |
| January | 20, 2021 | Mavericks | 90 | Spurs | 93 |
| January | 22, 2021 | Rockets | 81 | Mavericks | 89 |
| January | 24, 2021 | Jazz | 85 | Mavericks | 100 |
| January | 25, 2021 | Mavericks | 83 | Sonics | 115 |
| January | 28, 2021 | Suns | 82 | Mavericks | 103 |
| January | 29, 2021 | Nuggets | 94 | Mavericks | 106 |
| January | 31, 2021 | Mavericks | 114 | Nuggets | 89 |
| February | 2, 2021 | Mavericks | | Wolves | |
| February | 4, 2021 | Kings | | Mavericks | |
| February | 8, 2021 | Heat | | Mavericks | |
| February | 12, 2021 | Mavericks | | Pelicans | |
| February | 13, 2021 | Mavericks | | Nuggets | |
| February | 14, 2021 | Mavericks | | Bulls | |
| February | 15, 2021 | Mavericks | | Raptors | |
| February | 17, 2021 | Mavericks | | Grizzlies | |
| February | 19, 2021 | Rockets | | Mavericks | |
| February | 20, 2021 | 76ers | | Mavericks | |
| February | 22, 2021 | Pelicans | | Mavericks | |
| February | 23, 2021 | Wolves | | Mavericks | |
| February | 24, 2021 | Mavericks | | Warriors | |
| February | 27, 2021 | Mavericks | | Suns | |
| March | 1, 2021 | Clippers | | Mavericks | |
| March | 4, 2021 | Warriors | | Mavericks | |
| March | 6, 2021 | Mavericks | | Lakers | |
| March | 8, 2021 | Knicks | | Mavericks | |
| March | 10, 2021 | Wolves | | Mavericks | |
| March | 13, 2021 | Rockets | | Mavericks | |
| March | 14, 2021 | Kings | | Mavericks | |
| March | 15, 2021 | Mavericks | | Spurs | |
| March | 20, 2021 | Wolves | | Mavericks | |
| March | 27, 2021 | Sonics | | Mavericks | |
| April | 2, 2021 | Lakers | | Mavericks | |
| April | 3, 2021 | Mavericks | | Knicks | |
| April | 5, 2021 | Pacers | | Mavericks | |
| April | 8, 2021 | Suns | | Mavericks | |
| April | 9, 2021 | Mavericks | | Sonics | |
| April | 10, 2021 | Mavericks | | Blazers | |
| April | 12, 2021 | Grizzlies | | Mavericks | |
| April | 15, 2021 | Suns | | Mavericks | |
| April | 17, 2021 | Sonics | | Mavericks | |
| April | 21, 2021 | Mavericks | | Heat | |
| April | 23, 2021 | Mavericks | | Lakers | |
| April | 24, 2021 | Celtics | | Mavericks | |
| April | 25, 2021 | Nets | | Mavericks | |