| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Celtics | 98 | Knicks | 102 |
| November | 3, 2020 | Knicks | 103 | 76ers | 98 |
| November | 4, 2020 | Knicks | 93 | Spurs | 106 |
| November | 6, 2020 | Knicks | 89 | Nets | 111 |
| November | 7, 2020 | 76ers | 101 | Knicks | 122 |
| November | 13, 2020 | Knicks | 96 | Pelicans | 134 |
| November | 15, 2020 | Bulls | 88 | Knicks | 107 |
| November | 17, 2020 | Raptors | 123 | Knicks | 99 |
| November | 19, 2020 | Knicks | 104 | Bucks | 109 |
| November | 21, 2020 | Blazers | 125 | Knicks | 121 |
| November | 24, 2020 | Grizzlies | 86 | Knicks | 103 |
| November | 26, 2020 | Pelicans | 92 | Knicks | 122 |
| November | 27, 2020 | Heat | 85 | Knicks | 109 |
| November | 28, 2020 | Knicks | 108 | Heat | 102 |
| November | 29, 2020 | Knicks | 99 | Nets | 104 |
| November | 30, 2020 | Knicks | 131 | Blazers | 121 |
| December | 2, 2020 | Knicks | 102 | Clippers | 103 |
| December | 4, 2020 | Knicks | 102 | Nets | 130 |
| December | 6, 2020 | Sonics | 108 | Knicks | 98 |
| December | 7, 2020 | Nets | 103 | Knicks | 129 |
| December | 9, 2020 | Pacers | 82 | Knicks | 109 |
| December | 10, 2020 | Heat | 84 | Knicks | 102 |
| December | 11, 2020 | Knicks | 95 | Pacers | 86 |
| December | 12, 2020 | 76ers | 103 | Knicks | 108 |
| December | 14, 2020 | Knicks | 127 | Raptors | 107 |
| December | 15, 2020 | Knicks | 103 | Bucks | 115 |
| December | 18, 2020 | Nets | 109 | Knicks | 95 |
| December | 19, 2020 | Knicks | 104 | Bulls | 91 |
| December | 23, 2020 | Knicks | 105 | Lakers | 103 |
| December | 25, 2020 | Jazz | 99 | Knicks | 111 |
| December | 26, 2020 | Raptors | 113 | Knicks | 96 |
| December | 28, 2020 | Knicks | 98 | Celtics | 101 |
| December | 30, 2020 | 76ers | 94 | Knicks | 96 |
| January | 4, 2021 | Knicks | 100 | Raptors | 115 |
| January | 5, 2021 | Knicks | 113 | Bucks | 112 |
| January | 8, 2021 | Knicks | 108 | Celtics | 100 |
| January | 9, 2021 | Knicks | 111 | Hawks | 114 |
| January | 10, 2021 | Knicks | 101 | Suns | 120 |
| January | 11, 2021 | Hawks | 123 | Knicks | 140 |
| January | 13, 2021 | Bucks | 101 | Knicks | 90 |
| January | 17, 2021 | Knicks | 87 | Pacers | 80 |
| January | 18, 2021 | Knicks | 110 | Nuggets | 113 |
| January | 24, 2021 | Grizzlies | 87 | Knicks | 83 |
| January | 26, 2021 | Heat | 106 | Knicks | 109 |
| January | 28, 2021 | Hawks | 104 | Knicks | 102 |
| January | 29, 2021 | Knicks | 97 | 76ers | 80 |
| January | 30, 2021 | Grizzlies | 88 | Knicks | 89 |
| January | 31, 2021 | Lakers | 74 | Knicks | 90 |
| February | 4, 2021 | Pacers | | Knicks | |
| February | 14, 2021 | Rockets | | Knicks | |
| February | 17, 2021 | Nuggets | | Knicks | |
| February | 18, 2021 | Wolves | | Knicks | |
| February | 19, 2021 | Knicks | | 76ers | |
| February | 22, 2021 | Knicks | | Warriors | |
| February | 25, 2021 | Knicks | | Pelicans | |
| February | 27, 2021 | Knicks | | Kings | |
| March | 2, 2021 | Spurs | | Knicks | |
| March | 4, 2021 | Celtics | | Knicks | |
| March | 5, 2021 | Warriors | | Knicks | |
| March | 7, 2021 | Clippers | | Knicks | |
| March | 8, 2021 | Knicks | | Mavericks | |
| March | 9, 2021 | Hawks | | Knicks | |
| March | 11, 2021 | Knicks | | Nets | |
| March | 17, 2021 | Celtics | | Knicks | |
| March | 18, 2021 | Celtics | | Knicks | |
| March | 19, 2021 | Knicks | | Pelicans | |
| March | 22, 2021 | Knicks | | Hawks | |
| March | 25, 2021 | Knicks | | Rockets | |
| March | 31, 2021 | Pelicans | | Knicks | |
| April | 1, 2021 | Knicks | | Bulls | |
| April | 3, 2021 | Mavericks | | Knicks | |
| April | 5, 2021 | Bulls | | Knicks | |
| April | 6, 2021 | Kings | | Knicks | |
| April | 7, 2021 | Heat | | Knicks | |
| April | 11, 2021 | Knicks | | Pelicans | |
| April | 14, 2021 | Suns | | Knicks | |
| April | 17, 2021 | Knicks | | Wolves | |
| April | 20, 2021 | Knicks | | Sonics | |
| April | 21, 2021 | Knicks | | Jazz | |
| April | 22, 2021 | Knicks | | Heat | |
| April | 23, 2021 | Knicks | | Grizzlies | |
| April | 26, 2021 | Knicks | | Grizzlies | |