| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Blazers | 118 | Jazz | 122 |
| November | 4, 2020 | Nets | 131 | Blazers | 104 |
| November | 6, 2020 | Blazers | 123 | 76ers | 130 |
| November | 12, 2020 | Mavericks | 121 | Blazers | 112 |
| November | 13, 2020 | Blazers | 113 | Warriors | 117 |
| November | 16, 2020 | Kings | 109 | Blazers | 116 |
| November | 17, 2020 | Pacers | 117 | Blazers | 119 |
| November | 20, 2020 | Blazers | 123 | Pelicans | 131 |
| November | 21, 2020 | Blazers | 125 | Knicks | 121 |
| November | 24, 2020 | Blazers | 103 | Jazz | 123 |
| November | 26, 2020 | Rockets | 124 | Blazers | 112 |
| November | 30, 2020 | Knicks | 131 | Blazers | 121 |
| December | 1, 2020 | Blazers | 102 | Kings | 112 |
| December | 2, 2020 | Blazers | 147 | Nets | 142 |
| December | 3, 2020 | Jazz | 121 | Blazers | 98 |
| December | 4, 2020 | Bucks | 142 | Blazers | 115 |
| December | 7, 2020 | Blazers | 100 | Sonics | 130 |
| December | 10, 2020 | Raptors | 112 | Blazers | 138 |
| December | 11, 2020 | Sonics | 115 | Blazers | 129 |
| December | 14, 2020 | Blazers | 114 | Sonics | 129 |
| December | 16, 2020 | Nuggets | 121 | Blazers | 96 |
| December | 18, 2020 | Heat | 127 | Blazers | 135 |
| December | 20, 2020 | Blazers | 126 | Wolves | 121 |
| December | 22, 2020 | Jazz | 134 | Blazers | 128 |
| December | 24, 2020 | Blazers | 117 | Heat | 109 |
| December | 25, 2020 | Blazers | 111 | Sonics | 120 |
| December | 26, 2020 | Pelicans | 114 | Blazers | 109 |
| December | 27, 2020 | Blazers | 102 | Mavericks | 111 |
| December | 28, 2020 | Blazers | 123 | Mavericks | 128 |
| December | 29, 2020 | Lakers | 117 | Blazers | 129 |
| January | 1, 2021 | Blazers | 97 | Spurs | 116 |
| January | 2, 2021 | Sonics | 131 | Blazers | 109 |
| January | 4, 2021 | Warriors | 122 | Blazers | 134 |
| January | 6, 2021 | Kings | 114 | Blazers | 96 |
| January | 10, 2021 | Clippers | 123 | Blazers | 117 |
| January | 11, 2021 | Blazers | 117 | Bucks | 106 |
| January | 12, 2021 | Kings | 109 | Blazers | 123 |
| January | 15, 2021 | Lakers | 78 | Blazers | 104 |
| January | 16, 2021 | Blazers | 116 | Warriors | 128 |
| January | 17, 2021 | Suns | 108 | Blazers | 104 |
| January | 19, 2021 | Wolves | 90 | Blazers | 118 |
| January | 21, 2021 | Wolves | 101 | Blazers | 132 |
| January | 23, 2021 | Warriors | 113 | Blazers | 115 |
| January | 26, 2021 | Blazers | 125 | Pacers | 123 |
| January | 27, 2021 | Nuggets | 106 | Blazers | 109 |
| January | 28, 2021 | Blazers | 122 | Spurs | 124 |
| February | 4, 2021 | Blazers | | Nuggets | |
| February | 8, 2021 | Blazers | | Rockets | |
| February | 10, 2021 | 76ers | | Blazers | |
| February | 11, 2021 | Sonics | | Blazers | |
| February | 14, 2021 | Blazers | | Lakers | |
| February | 17, 2021 | Blazers | | Suns | |
| February | 20, 2021 | Blazers | | Kings | |
| February | 23, 2021 | Celtics | | Blazers | |
| March | 1, 2021 | Blazers | | Nuggets | |
| March | 6, 2021 | Blazers | | Kings | |
| March | 9, 2021 | Rockets | | Blazers | |
| March | 12, 2021 | Blazers | | Rockets | |
| March | 13, 2021 | Blazers | | Raptors | |
| March | 15, 2021 | Clippers | | Blazers | |
| March | 19, 2021 | Blazers | | Warriors | |
| March | 21, 2021 | Hawks | | Blazers | |
| March | 22, 2021 | Bulls | | Blazers | |
| March | 24, 2021 | Blazers | | Bulls | |
| March | 28, 2021 | Lakers | | Blazers | |
| March | 31, 2021 | Clippers | | Blazers | |
| April | 1, 2021 | Blazers | | Wolves | |
| April | 3, 2021 | Blazers | | Suns | |
| April | 5, 2021 | Suns | | Blazers | |
| April | 6, 2021 | Grizzlies | | Blazers | |
| April | 9, 2021 | Blazers | | Clippers | |
| April | 10, 2021 | Mavericks | | Blazers | |
| April | 11, 2021 | Spurs | | Blazers | |
| April | 13, 2021 | Blazers | | Grizzlies | |
| April | 14, 2021 | Blazers | | Celtics | |
| April | 15, 2021 | Blazers | | Lakers | |
| April | 19, 2021 | Blazers | | Clippers | |
| April | 21, 2021 | Warriors | | Blazers | |
| April | 22, 2021 | Spurs | | Blazers | |
| April | 23, 2021 | Blazers | | Hawks | |
| April | 24, 2021 | Blazers | | Clippers | |
| April | 25, 2021 | Blazers | | Lakers | |