| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Knicks | 103 | 76ers | 98 |
| November | 4, 2020 | 76ers | 107 | Bucks | 106 |
| November | 5, 2020 | 76ers | 88 | Celtics | 124 |
| November | 6, 2020 | Blazers | 123 | 76ers | 130 |
| November | 7, 2020 | 76ers | 101 | Knicks | 122 |
| November | 9, 2020 | Bulls | 80 | 76ers | 122 |
| November | 14, 2020 | 76ers | 115 | Bulls | 107 |
| November | 18, 2020 | Bucks | 129 | 76ers | 127 |
| November | 22, 2020 | 76ers | 89 | Pacers | 96 |
| November | 23, 2020 | Celtics | 105 | 76ers | 73 |
| November | 24, 2020 | 76ers | 100 | Nets | 85 |
| November | 27, 2020 | 76ers | 113 | Kings | 99 |
| November | 29, 2020 | Pacers | 75 | 76ers | 94 |
| December | 2, 2020 | Heat | 91 | 76ers | 108 |
| December | 3, 2020 | 76ers | 121 | Nuggets | 96 |
| December | 4, 2020 | Rockets | 90 | 76ers | 111 |
| December | 5, 2020 | 76ers | 79 | Heat | 100 |
| December | 7, 2020 | Warriors | 111 | 76ers | 106 |
| December | 12, 2020 | 76ers | 103 | Knicks | 108 |
| December | 13, 2020 | 76ers | 76 | Nets | 102 |
| December | 17, 2020 | 76ers | 112 | Bucks | 119 |
| December | 18, 2020 | Pelicans | 115 | 76ers | 104 |
| December | 20, 2020 | Hawks | 105 | 76ers | 108 |
| December | 21, 2020 | Raptors | 102 | 76ers | 97 |
| December | 23, 2020 | 76ers | 111 | Pelicans | 120 |
| December | 25, 2020 | Grizzlies | 84 | 76ers | 90 |
| December | 26, 2020 | 76ers | 81 | Celtics | 108 |
| December | 27, 2020 | 76ers | 101 | Suns | 104 |
| December | 28, 2020 | Heat | 111 | 76ers | 101 |
| December | 30, 2020 | 76ers | 94 | Knicks | 96 |
| January | 2, 2021 | Heat | 97 | 76ers | 88 |
| January | 4, 2021 | Grizzlies | 92 | 76ers | 87 |
| January | 6, 2021 | 76ers | 119 | Celtics | 106 |
| January | 7, 2021 | Mavericks | 88 | 76ers | 105 |
| January | 8, 2021 | 76ers | 92 | Wolves | 86 |
| January | 13, 2021 | 76ers | 87 | Nets | 100 |
| January | 14, 2021 | Bucks | 118 | 76ers | 113 |
| January | 15, 2021 | Kings | 79 | 76ers | 100 |
| January | 17, 2021 | Jazz | 115 | 76ers | 93 |
| January | 19, 2021 | 76ers | 108 | Warriors | 107 |
| January | 22, 2021 | Celtics | 114 | 76ers | 119 |
| January | 23, 2021 | Wolves | 93 | 76ers | 103 |
| January | 25, 2021 | 76ers | 93 | Rockets | 103 |
| January | 29, 2021 | Knicks | 97 | 76ers | 80 |
| January | 30, 2021 | 76ers | 77 | Bulls | 108 |
| January | 31, 2021 | 76ers | 95 | Sonics | 117 |
| February | 8, 2021 | 76ers | | Raptors | |
| February | 9, 2021 | 76ers | | Lakers | |
| February | 10, 2021 | 76ers | | Blazers | |
| February | 11, 2021 | Raptors | | 76ers | |
| February | 12, 2021 | 76ers | | Clippers | |
| February | 13, 2021 | 76ers | | Grizzlies | |
| February | 14, 2021 | Pelicans | | 76ers | |
| February | 15, 2021 | Nets | | 76ers | |
| February | 17, 2021 | 76ers | | Hawks | |
| February | 19, 2021 | Knicks | | 76ers | |
| February | 20, 2021 | 76ers | | Mavericks | |
| February | 23, 2021 | Clippers | | 76ers | |
| February | 26, 2021 | Nets | | 76ers | |
| February | 28, 2021 | 76ers | | Spurs | |
| March | 1, 2021 | Lakers | | 76ers | |
| March | 5, 2021 | 76ers | | Grizzlies | |
| March | 7, 2021 | 76ers | | Celtics | |
| March | 10, 2021 | Hawks | | 76ers | |
| March | 11, 2021 | 76ers | | Jazz | |
| March | 12, 2021 | 76ers | | Pelicans | |
| March | 14, 2021 | 76ers | | Hawks | |
| March | 16, 2021 | Raptors | | 76ers | |
| March | 21, 2021 | Bulls | | 76ers | |
| March | 27, 2021 | Pelicans | | 76ers | |
| March | 29, 2021 | 76ers | | Pacers | |
| March | 30, 2021 | Sonics | | 76ers | |
| March | 31, 2021 | 76ers | | Raptors | |
| April | 2, 2021 | 76ers | | Heat | |
| April | 6, 2021 | 76ers | | Heat | |
| April | 8, 2021 | Spurs | | 76ers | |
| April | 9, 2021 | Bulls | | 76ers | |
| April | 12, 2021 | Pacers | | 76ers | |
| April | 13, 2021 | 76ers | | Pelicans | |
| April | 16, 2021 | Nuggets | | 76ers | |
| April | 18, 2021 | Nets | | 76ers | |
| April | 19, 2021 | Suns | | 76ers | |