| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Blazers | 92 | Jazz | 127 |
| November | 4, 2020 | Nets | 140 | Blazers | 91 |
| November | 6, 2020 | Blazers | 144 | 76ers | 126 |
| November | 12, 2020 | Mavericks | 118 | Blazers | 112 |
| November | 13, 2020 | Blazers | 119 | Warriors | 95 |
| November | 16, 2020 | Kings | 117 | Blazers | 120 |
| November | 17, 2020 | Pacers | 124 | Blazers | 111 |
| November | 20, 2020 | Blazers | 113 | Pelicans | 124 |
| November | 21, 2020 | Blazers | 119 | Knicks | 129 |
| November | 24, 2020 | Blazers | 103 | Jazz | 127 |
| November | 26, 2020 | Rockets | 123 | Blazers | 102 |
| November | 30, 2020 | Knicks | 125 | Blazers | 117 |
| December | 1, 2020 | Blazers | 92 | Kings | 115 |
| December | 2, 2020 | Blazers | 95 | Nets | 132 |
| December | 3, 2020 | Jazz | 125 | Blazers | 113 |
| December | 4, 2020 | Bucks | 124 | Blazers | 113 |
| December | 7, 2020 | Blazers | 108 | Sonics | 128 |
| December | 10, 2020 | Raptors | 121 | Blazers | 101 |
| December | 11, 2020 | Sonics | 97 | Blazers | 108 |
| December | 14, 2020 | Blazers | 118 | Sonics | 134 |
| December | 16, 2020 | Nuggets | 110 | Blazers | 133 |
| December | 18, 2020 | Heat | 130 | Blazers | 128 |
| December | 20, 2020 | Blazers | 133 | Wolves | 126 |
| December | 22, 2020 | Jazz | 130 | Blazers | 127 |
| December | 24, 2020 | Blazers | 115 | Heat | 123 |
| December | 25, 2020 | Blazers | 108 | Sonics | 100 |
| December | 26, 2020 | Pelicans | 123 | Blazers | 115 |
| December | 27, 2020 | Blazers | 87 | Mavericks | 103 |
| December | 28, 2020 | Blazers | 103 | Mavericks | 124 |
| December | 29, 2020 | Lakers | 120 | Blazers | 103 |
| January | 1, 2021 | Blazers | 133 | Spurs | 130 |
| January | 2, 2021 | Sonics | 119 | Blazers | 125 |
| January | 4, 2021 | Warriors | 125 | Blazers | 130 |
| January | 6, 2021 | Kings | 112 | Blazers | 131 |
| January | 10, 2021 | Clippers | 107 | Blazers | 120 |
| January | 11, 2021 | Blazers | 120 | Bucks | 126 |
| January | 12, 2021 | Kings | 110 | Blazers | 144 |
| January | 15, 2021 | Lakers | 136 | Blazers | 122 |
| January | 16, 2021 | Blazers | 135 | Warriors | 104 |
| January | 17, 2021 | Suns | 119 | Blazers | 126 |
| January | 19, 2021 | Wolves | 134 | Blazers | 133 |
| January | 21, 2021 | Wolves | 124 | Blazers | 122 |
| January | 23, 2021 | Warriors | 117 | Blazers | 132 |
| January | 26, 2021 | Blazers | 112 | Pacers | 138 |
| January | 27, 2021 | Nuggets | 116 | Blazers | 123 |
| January | 28, 2021 | Blazers | 124 | Spurs | 134 |
| February | 4, 2021 | Blazers | 110 | Nuggets | 136 |
| February | 8, 2021 | Blazers | 108 | Rockets | 128 |
| February | 10, 2021 | 76ers | 111 | Blazers | 108 |
| February | 11, 2021 | Sonics | 120 | Blazers | 103 |
| February | 14, 2021 | Blazers | 113 | Lakers | 121 |
| February | 17, 2021 | Blazers | 122 | Suns | 87 |
| February | 20, 2021 | Blazers | 107 | Kings | 113 |
| February | 23, 2021 | Celtics | 130 | Blazers | 119 |
| March | 1, 2021 | Blazers | 111 | Nuggets | 145 |
| March | 6, 2021 | Blazers | 103 | Kings | 139 |
| March | 9, 2021 | Rockets | 121 | Blazers | 124 |
| March | 12, 2021 | Blazers | 94 | Rockets | 122 |
| March | 13, 2021 | Blazers | 112 | Raptors | 118 |
| March | 15, 2021 | Clippers | 109 | Blazers | 125 |
| March | 19, 2021 | Blazers | 114 | Warriors | 135 |
| March | 21, 2021 | Hawks | 100 | Blazers | 115 |
| March | 22, 2021 | Bulls | 109 | Blazers | 143 |
| March | 24, 2021 | Blazers | 137 | Bulls | 131 |
| March | 28, 2021 | Lakers | 141 | Blazers | 122 |
| March | 31, 2021 | Clippers | 113 | Blazers | 127 |
| April | 1, 2021 | Blazers | 112 | Wolves | 122 |
| April | 3, 2021 | Blazers | 123 | Suns | 111 |
| April | 5, 2021 | Suns | 110 | Blazers | 113 |
| April | 6, 2021 | Grizzlies | 102 | Blazers | 127 |
| April | 9, 2021 | Blazers | 118 | Clippers | 121 |
| April | 10, 2021 | Mavericks | 111 | Blazers | 110 |
| April | 11, 2021 | Spurs | 113 | Blazers | 117 |
| April | 13, 2021 | Blazers | 121 | Grizzlies | 119 |
| April | 14, 2021 | Blazers | 131 | Celtics | 127 |
| April | 15, 2021 | Blazers | 107 | Lakers | 138 |
| April | 19, 2021 | Blazers | 119 | Clippers | 123 |
| April | 21, 2021 | Warriors | 123 | Blazers | 120 |
| April | 22, 2021 | Spurs | 114 | Blazers | 123 |
| April | 23, 2021 | Blazers | 100 | Hawks | 111 |
| April | 24, 2021 | Blazers | 122 | Clippers | 131 |
| April | 25, 2021 | Blazers | 126 | Lakers | 142 |