| month | day | visitor | score | home | score |
|---|
| November | 3, 2021 | Nuggets | 108 | Grizzlies | 112 |
| November | 4, 2021 | Nuggets | 121 | Wolves | 109 |
| November | 5, 2021 | Nuggets | 111 | Raptors | 117 |
| November | 6, 2021 | Nuggets | 110 | Suns | 119 |
| November | 12, 2021 | Lakers | 115 | Nuggets | 138 |
| November | 13, 2021 | Nuggets | 111 | Wolves | 114 |
| November | 15, 2021 | Nuggets | 127 | Jazz | 110 |
| November | 18, 2021 | Sonics | 107 | Nuggets | 111 |
| November | 20, 2021 | Rockets | 81 | Nuggets | 123 |
| November | 21, 2021 | Nuggets | 123 | Clippers | 112 |
| November | 26, 2021 | Mavericks | 132 | Nuggets | 127 |
| December | 1, 2021 | Rockets | 117 | Nuggets | 111 |
| December | 2, 2021 | Nuggets | 103 | Suns | 112 |
| December | 3, 2021 | 76ers | 118 | Nuggets | 114 |
| December | 5, 2021 | Nuggets | 113 | Mavericks | 122 |
| December | 10, 2021 | Nuggets | 134 | Spurs | 109 |
| December | 13, 2021 | Nuggets | 112 | Celtics | 132 |
| December | 15, 2021 | Jazz | 112 | Nuggets | 130 |
| December | 16, 2021 | Nuggets | 107 | Blazers | 86 |
| December | 23, 2021 | Suns | 95 | Nuggets | 124 |
| December | 24, 2021 | Nuggets | 107 | Kings | 86 |
| December | 27, 2021 | Pacers | 98 | Nuggets | 113 |
| December | 30, 2021 | Nuggets | 118 | Jazz | 111 |
| January | 3, 2022 | Nuggets | 110 | Rockets | 106 |
| January | 6, 2022 | Sonics | 102 | Nuggets | 110 |
| January | 7, 2022 | Nuggets | 125 | Hawks | 114 |
| January | 9, 2022 | Nuggets | 100 | Sonics | 130 |
| January | 12, 2022 | Suns | 106 | Nuggets | 122 |
| January | 13, 2022 | Kings | 93 | Nuggets | 83 |
| January | 14, 2022 | Nuggets | 97 | Rockets | 102 |
| January | 18, 2022 | Knicks | 112 | Nuggets | 121 |
| January | 20, 2022 | Lakers | 90 | Nuggets | 123 |
| January | 22, 2022 | Nuggets | 117 | Suns | 122 |
| January | 27, 2022 | Nuggets | 92 | Blazers | 88 |
| January | 29, 2022 | Nuggets | 130 | Mavericks | 116 |
| January | 31, 2022 | Mavericks | 134 | Nuggets | 136 |
| February | 2, 2022 | Spurs | 116 | Nuggets | 127 |
| February | 4, 2022 | Blazers | 116 | Nuggets | 98 |
| February | 8, 2022 | Nuggets | 120 | Lakers | 98 |
| February | 9, 2022 | Bulls | 110 | Nuggets | 122 |
| February | 13, 2022 | Mavericks | 104 | Nuggets | 143 |
| February | 17, 2022 | Nuggets | 101 | Knicks | 104 |
| February | 18, 2022 | Pelicans | 102 | Nuggets | 121 |
| February | 19, 2022 | Nets | 98 | Nuggets | 112 |
| February | 21, 2022 | Spurs | 101 | Nuggets | 119 |
| February | 22, 2022 | Wolves | 117 | Nuggets | 112 |
| February | 23, 2022 | Raptors | 113 | Nuggets | 135 |
| February | 25, 2022 | Nuggets | 114 | Heat | 92 |
| February | 27, 2022 | Clippers | 121 | Nuggets | 125 |
| March | 1, 2022 | Blazers | 99 | Nuggets | 84 |
| March | 3, 2022 | Wolves | 89 | Nuggets | 123 |
| March | 4, 2022 | Spurs | 87 | Nuggets | 114 |
| March | 5, 2022 | Nuggets | 79 | Kings | 84 |
| March | 8, 2022 | Nuggets | 127 | Jazz | 129 |
| March | 11, 2022 | Clippers | 116 | Nuggets | 131 |
| March | 13, 2022 | Nuggets | 107 | Warriors | 111 |
| March | 15, 2022 | Nuggets | 115 | Pelicans | 102 |
| March | 17, 2022 | Nuggets | 153 | Bucks | 115 |
| March | 19, 2022 | Nuggets | 139 | Lakers | 121 |
| March | 20, 2022 | Nuggets | 115 | Rockets | 130 |
| March | 21, 2022 | Grizzlies | 104 | Nuggets | 102 |
| March | 22, 2022 | Celtics | 133 | Nuggets | 122 |
| March | 24, 2022 | Nuggets | 106 | Wolves | 110 |
| March | 26, 2022 | Suns | 121 | Nuggets | 110 |
| March | 27, 2022 | Nuggets | 118 | Warriors | 93 |
| March | 29, 2022 | Bucks | 112 | Nuggets | 132 |
| March | 30, 2022 | Jazz | 115 | Nuggets | 132 |
| March | 31, 2022 | Nuggets | 134 | Bulls | 106 |
| April | 1, 2022 | Nuggets | 121 | Clippers | 124 |
| April | 2, 2022 | Warriors | 104 | Nuggets | 124 |
| April | 3, 2022 | Nuggets | 111 | Sonics | 96 |
| April | 4, 2022 | Wolves | 116 | Nuggets | 133 |
| April | 7, 2022 | Kings | 73 | Nuggets | 103 |
| April | 8, 2022 | Nuggets | 121 | Pacers | 104 |
| April | 10, 2022 | Nuggets | 123 | Spurs | 100 |
| April | 12, 2022 | Heat | 92 | Nuggets | 111 |
| April | 13, 2022 | Warriors | 113 | Nuggets | 107 |
| April | 15, 2022 | Nuggets | 115 | Nets | 121 |
| April | 16, 2022 | Nuggets | 107 | 76ers | 114 |
| April | 17, 2022 | Jazz | 107 | Nuggets | 129 |
| April | 24, 2022 | Hawks | 107 | Nuggets | 126 |
| April | 25, 2022 | Nuggets | 100 | Spurs | 116 |
| Post | 1, 2022 | Mavericks | 126 | Nuggets | 108 |
| Post | 2, 2022 | Mavericks | 108 | Nuggets | 125 |
| Post | 3, 2022 | Nuggets | 113 | Mavericks | 143 |
| Post | 4, 2022 | Nuggets | 123 | Mavericks | 100 |
| Post | 5, 2022 | Mavericks | 100 | Nuggets | 112 |
| Post | 6, 2022 | Nuggets | 97 | Mavericks | 131 |
| Post | 7, 2022 | Mavericks | 110 | Nuggets | 134 |
| Post | 8, 2022 | Nuggets | 122 | Rockets | 123 |
| Post | 9, 2022 | Nuggets | 122 | Rockets | 127 |
| Post | 10, 2022 | Rockets | 120 | Nuggets | 126 |
| Post | 11, 2022 | Rockets | 115 | Nuggets | 109 |
| Post | 12, 2022 | Nuggets | 103 | Rockets | 116 |
| Post | 13, 2022 | Rockets | | Nuggets | |
| Post | 14, 2022 | Nuggets | | Rockets | |