| month | day | visitor | score | home | score |
|---|
| November | 4, 2018 | Knicks | 109 | Spurs | 106 |
| November | 5, 2018 | Spurs | 103 | Heat | 90 |
| November | 10, 2018 | Spurs | 109 | Wolves | 137 |
| November | 13, 2018 | Lakers | 106 | Spurs | 91 |
| November | 15, 2018 | Rockets | 109 | Spurs | 108 |
| November | 18, 2018 | Spurs | 91 | Mavericks | 120 |
| November | 19, 2018 | Grizzlies | 85 | Spurs | 90 |
| November | 22, 2018 | Jazz | 109 | Spurs | 126 |
| November | 27, 2018 | Jazz | 76 | Spurs | 110 |
| November | 29, 2018 | Suns | 100 | Spurs | 118 |
| December | 5, 2018 | Jazz | 97 | Spurs | 116 |
| December | 6, 2018 | Spurs | 119 | Clippers | 97 |
| December | 7, 2018 | Bucks | 98 | Spurs | 100 |
| December | 8, 2018 | Wolves | 96 | Spurs | 124 |
| December | 10, 2018 | Nuggets | 119 | Spurs | 105 |
| December | 11, 2018 | Warriors | 106 | Spurs | 83 |
| December | 13, 2018 | Hawks | 92 | Spurs | 104 |
| December | 15, 2018 | Spurs | 113 | Celtics | 129 |
| December | 17, 2018 | Spurs | 107 | Rockets | 113 |
| December | 20, 2018 | Spurs | 123 | Mavericks | 133 |
| December | 21, 2018 | Spurs | 93 | Pelicans | 113 |
| December | 22, 2018 | Mavericks | 96 | Spurs | 107 |
| December | 23, 2018 | Pacers | 90 | Spurs | 107 |
| December | 31, 2018 | Kings | 108 | Spurs | 106 |
| January | 1, 2019 | Blazers | 80 | Spurs | 113 |
| January | 2, 2019 | Nets | 93 | Spurs | 103 |
| January | 3, 2019 | Spurs | 92 | Kings | 97 |
| January | 5, 2019 | Lakers | 101 | Spurs | 108 |
| January | 7, 2019 | Spurs | 104 | Sonics | 115 |
| January | 8, 2019 | Sonics | 107 | Spurs | 113 |
| January | 9, 2019 | Spurs | 109 | Clippers | 95 |
| January | 11, 2019 | Clippers | 73 | Spurs | 98 |
| January | 14, 2019 | Spurs | 107 | Wolves | 119 |
| January | 17, 2019 | Spurs | 91 | Mavericks | 105 |
| January | 20, 2019 | Mavericks | 103 | Spurs | 90 |
| January | 21, 2019 | Clippers | 93 | Spurs | 109 |
| January | 25, 2019 | Spurs | 107 | Bulls | 82 |
| January | 27, 2019 | Spurs | 91 | Jazz | 109 |
| January | 28, 2019 | Blazers | 99 | Spurs | 100 |
| January | 29, 2019 | Spurs | 98 | Bucks | 124 |
| February | 1, 2019 | Kings | 94 | Spurs | 81 |
| February | 2, 2019 | Spurs | 126 | Nuggets | 112 |
| February | 4, 2019 | Heat | 81 | Spurs | 103 |
| February | 9, 2019 | Spurs | 104 | Jazz | 97 |
| February | 11, 2019 | Pelicans | 102 | Spurs | 117 |
| February | 12, 2019 | Warriors | 89 | Spurs | 105 |
| February | 13, 2019 | Spurs | 91 | Kings | 108 |
| February | 15, 2019 | Spurs | 102 | Rockets | 130 |
| February | 16, 2019 | Bulls | 105 | Spurs | 83 |
| February | 21, 2019 | Spurs | 117 | Nuggets | 123 |
| February | 24, 2019 | Wolves | 120 | Spurs | 108 |
| February | 26, 2019 | Spurs | 101 | Hawks | 86 |
| February | 28, 2019 | 76ers | 118 | Spurs | 103 |
| March | 2, 2019 | Spurs | 96 | Knicks | 105 |
| March | 3, 2019 | Spurs | 113 | Sonics | 105 |
| March | 4, 2019 | Spurs | 110 | Nuggets | 113 |
| March | 6, 2019 | Rockets | 126 | Spurs | 106 |
| March | 8, 2019 | Spurs | 102 | Suns | 115 |
| March | 9, 2019 | Spurs | 98 | Lakers | 118 |
| March | 11, 2019 | Sonics | 98 | Spurs | 85 |
| March | 12, 2019 | Spurs | 105 | Lakers | 88 |
| March | 15, 2019 | Mavericks | 97 | Spurs | 114 |
| March | 21, 2019 | Celtics | 107 | Spurs | 85 |
| March | 23, 2019 | Spurs | 123 | Warriors | 127 |
| March | 27, 2019 | Spurs | 95 | Nets | 92 |
| March | 29, 2019 | Spurs | 96 | Grizzlies | 91 |
| March | 30, 2019 | Spurs | 112 | Suns | 90 |
| April | 1, 2019 | Rockets | 100 | Spurs | 110 |
| April | 3, 2019 | Spurs | 118 | Wolves | 120 |
| April | 4, 2019 | Raptors | 87 | Spurs | 108 |
| April | 7, 2019 | Suns | 93 | Spurs | 111 |
| April | 8, 2019 | Spurs | 110 | 76ers | 114 |
| April | 9, 2019 | Spurs | 91 | Warriors | 102 |
| April | 10, 2019 | Nuggets | 91 | Spurs | 100 |
| April | 11, 2019 | Spurs | 104 | Blazers | 98 |
| April | 12, 2019 | Spurs | 101 | Jazz | 108 |
| April | 13, 2019 | Wolves | 110 | Spurs | 107 |
| April | 14, 2019 | Spurs | 123 | Raptors | 97 |
| April | 16, 2019 | Spurs | 120 | Suns | 107 |
| April | 22, 2019 | Spurs | 95 | Blazers | 107 |
| April | 24, 2019 | Spurs | 68 | Pacers | 112 |
| April | 25, 2019 | Nuggets | 99 | Spurs | 122 |
| Post | 1, 2019 | Spurs | 84 | Sonics | 97 |
| Post | 2, 2019 | Spurs | 98 | Sonics | 108 |
| Post | 3, 2019 | Sonics | 116 | Spurs | 117 |
| Post | 4, 2019 | Sonics | 104 | Spurs | 85 |
| Post | 5, 2019 | Spurs | 104 | Sonics | 115 |
| Post | 6, 2019 | Sonics | | Spurs | |
| Post | 7, 2019 | Spurs | | Sonics | |